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朱敏生
Medical School
南京大学
江苏
Language: 中文, 英语
肠道微生物
平滑肌
生理学
胃肠动力
哮喘
高血压
肥胖
疾病机制
转化研究
小鼠遗传学
Areas of Focus
- 肠道微生物与平滑肌生理学
Work Experience
- 1999-2001 - 德州大学西南医学中心 - 博士后研究员
- 2004至今 - 南京大学 - 教授
Academic Background & Achievements
- 1995 博士: 中国科学院上海生物化学研究所
- 成就: 在《Gastroenterology》、《J Clin Invest》、《PNAS》等顶级期刊上发表研究成果
- 成就: 2016年国家科技进步二等奖
Publications
- Tas2R激活通过释放Gαt靶向AChR信号放松气道平滑肌, Zhou YW, Sun J, Wang Y, Chen CP, Tao T, Ma M, Chen X, Zhang XN, Yang LY, Zhang ZL, Li YQ, Jiang ZH, Qiu TT, Wang H, Pan Y, Zhang J, Chen HQ, Wang P, Zhu MS, 2022
- 一种志贺氏菌变种与难治性功能性便秘有因果关系, Chen X, Qiu TT, Wang Y, Xu LY, Sun J, Jiang ZH, Zhao W, Tao T, Zhou YW, Wei L, Li Y, Zheng Y, Zhou GH, Chen H, Zhang J, Feng XB, Wang F, Li N, Zhang XN, Jiang J, Zhu MS, 2022
- 胸腺通过直接促进卫星细胞扩增来调节骨骼肌再生, Zheng YY, Wang Y, Chen X, Wei LS, Wang H, Tao T, Zhou YW, Jiang ZH, Qiu TT, Sun ZY, Sun J, Wang P, Zhao W, Li YQ, Chen HQ, Zhu MS, Zhang XN, 2022
- LIMK2是收缩气道平滑肌膜细胞骨架重组所必需的, Li Y, Zhou Y, Wang P, Tao T, Wei L, Wang Y, Wang W, Zheng Y, Jiang Z, Qiu T, Zhao W, Sun J, Chen X, Zhang XN, Zhu MS, 2021
- GGPP耗竭通过失衡CYB5R3依赖的花生四烯酸代谢引发代谢炎症, Li-sha Wei, Yan-Yan Zheng, Jie Sun, Pei Wang, Tao Tao, Yeqiong Li, Xin Chen, Yongjuan Sang, Danyang Chong, Wei Zhao, Yuwei Zhou, Ye Wang, Zhihui Jiang, Tiantian Qiu, Chao-Jun Li, Min-Sheng Zhu, Xuena Zhang, 2020
- DNM2基因内的MIR199A1对X连锁中心核肌病的病理有贡献, Chen X, Yun-Qian Gao, Yan-Yan Zheng, Wei Wang, Pei Wang, Juan Liang, Wei Zhao, Tao Tao, Jie Sun, Li-Sha Wei, Ye-Qiong Li, Yu-Wei Zhou, Zhen-Ji Gan, Xue-Na Zhang, Hua-Qun Chen, Min-Sheng Zhu, 2020
- CPI-17介导的血管平滑肌收缩对肥胖小鼠高血压的发展至关重要, Sun J, Tao T, Zhao W, Wei LS, She F, Wang P, Li Y, Zheng Y, Chen X, Wang W, Qiao YN, Zhang XN, Zhu MS, 2019
- 高尔基体驻留的TRIO在神经突生长期间调节膜运输, Tao T, Sun J, Peng YJ, Li Y, Wang P, Chen X, Zhao W, Zheng YY, Wei LS, Wang W, Zhou YW, Liu J, Shi YS, Zhu MS, 2019
- 炎症介质通过GPCR-TMEM16A-VDCC轴介导气道平滑肌收缩并导致哮喘中的支气管高反应性, Pei Wang, Wei Zhao, Jie Sun, Tao Tao, Xin Chen, Yan-Yan Zheng, Cheng-Hai Zhang, Zhong Chen, Yun-Qian Gao, Fan She, Ye-Qiong Li, Li-Sha Wei, Ping Lu, Cai-Ping Chen, Ji Zhou, Da-Quan Wang, Liang Chen, Xiao-Hao Shi, Linhong Deng, Ronghua ZhuGe, Hua-Qun Chen, Min-Sheng Zhu, 2018
- 一种没有目标序列限制的DNA编辑的新工具：结构引导的核酸酶, Xu S, Cao S, Zou B, Yue Y, Gu C, Chen X, Wang P, Dong X, Xiang Z, Li K, Zhu MS, Zhao QS, Zhou GH, 2016
- 内肛门括约肌基础张力生成的分子基础, Zhang CH, Wang P, Chen CP, Zhao W, Chen X, Chen C, He WQ, Qiao YN, Tao T, Sun J, Peng YJ, Craige SM, Lifshitz LM, Jr KJF, Fogarty KE, ZhuGe R, Zhu MS, 2016
- 母系表达的miR-379-544簇对DLK1的调控可能是Callipyge极性过度显性遗传的基础, Gao YQ, Chen X, Wang P, Lu L, Zhao W, Chen C, Chen CP, Tao T, Sun J, Zheng YY, Du Jie, Li CJ, Gan ZJ, Gao X, Chen HQ, Zhu MS, 2015
- 肌球蛋白磷酸酶靶向亚基-1 T694和T852磷酸化位点在膀胱平滑肌中的体内作用, Chen, C.P., Chen, X., Qiao, Y.N., Wang, P., He, W. Q., Zhang, C.H., Zhao, W., Gao, Y.Q., Chen, C., Tao, T., Sun, J., Wang, Y., Gao, N., Kamm, K.E., Stull, J.T., and Zhu, M.S, 2015
Awards
- 2016年国家科技进步二等奖: 基因工程小鼠等相关疾病模型研发与应用
