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Qin Jinzhong
Medical School
Nanjing University
Jiangsu
Language: English, Chinese
Stem Cells
Regenerative Medicine
Epigenetic Regulation
Polycomb Proteins
Gene Regulation
Cell Proliferation
Cell Differentiation
Embryonic Development
Tumorigenesis
Therapeutic Applications
Areas of Focus
- Stem Cell and Regenerative Medicine
Work Experience
- 2000-2005: PhD Research at Cleveland State University
- 2005-2008: Postdoctoral Research at Massachusetts General Hospital, Harvard Stem Cell and Regenerative Biology Institute, Harvard Medical School
- 2008-2013: Assistant in Genetics at Massachusetts General Hospital
- 2013-present: Researcher at Nanjing University Model Animal Research Institute
Academic Background & Achievements
- 2000-2005: PhD in Biology, Cleveland State University
- Postdoctoral Research: Massachusetts General Hospital, Harvard Stem Cell and Regenerative Biology Institute, Harvard Medical School
- 2013: Recruited by Nanjing University through the High-Level Talent Introduction Program
- 2015: Received support from Jiangsu Province Dual Innovation Talent Program
Publications
- Functional redundancy among Polycomb complexes in maintaining the pluripotent state of embryonic stem cells, Zhu Y, Dong L, Wang C, Hao K, Wang J, Zhao L, Xu L, Xia Y, Jiang Q, Qin J., 2022
- The MuvB complex safeguards embryonic stem cell identity through regulation of the cell cycle machinery, Wang C, Hao K, Dong L, Wang J, Zhao L, Xu L, Xia Y, Jiang Q, Qin J., 2022
- Rbbp4 Suppresses Premature Differentiation of Embryonic Stem Cells, Huang Y, Su T, Wang C, Dong L, Liu S, Zhu Y, Hao K, Xia Y, Jiang Q, Qin J., 2021
- Mga safeguards embryonic stem cells from acquiring extraembryonic endoderm fates, Qin J, Wang C, Zhu Y, Su T, Dong L, Huang Y, Hao K., 2021
- The polycomb group protein PCGF6 mediates germline gene silencing by recruiting histone-modifying proteins to target gene promoters, Liu M, Zhu Y, Xing F, Liu S, Xia Y, Jiang Q, Qin J., 2020
- The polycomb group protein Yaf2 regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner, Zhao W, Liu M, Ji H, Zhu Y, Wang C, Huang Y, Ma X, Xing G, Xia Y, Jiang Q, Qin J., 2018
- Lethal (3) malignant brain tumor-like 2 (L3MBTL2) protein protects against kidney injury by inhibiting the DNA damage-p53-apoptosis pathway in renal tubular cells, Huang H, Xu C, Wang Y, Meng C, Liu W, Zhao Y, Huang XR, You W, Feng B, Zheng ZH, Huang Y, Lan HY, Qin J, Xia Y., 2018
- Combinatorial Control of Recruitment of a Variant PRC1.6 Complex in Embryonic Stem Cells, Huang Y, Zhao W, Wang C, Zhu Y, Liu M, Tong H, Xia Y, Jiang Q, Qin J., 2018
- Polycomb group RING finger proteins 3/5 activate transcription via an interaction with the pluripotency factor Tex10 in embryonic stem cells, Zhao W, Huang Y, Zhang J, Liu M, Ji H, Wang C, Cao N, Li C, Xia Y, Jiang Q, Qin J., 2017
- Loss of Polycomb Group Protein Pcgf1 Severely Compromises Proper Differentiation of Embryonic Stem Cells, Yan Y, Zhao W, Huang Y, Tong H, Xia Y, Jiang Q, Qin J., 2017
- Essential Role for Polycomb Group Protein Pcgf6 in Embryonic Stem Cell Maintenance and a Noncanonical Polycomb Repressive Complex 1 (PRC1) Integrity, Zhao W, Tong H, Huang Y, Yan Y, Teng H, Xia Y, Jiang Q, Qin J., 2017
Awards
- MGH ECOR Fund for Medical Discovery Award
- NIH Training Grant T32 2012D006265
- P50 NIH Mount Sinai School of Medicine
