Professor | Shaolin Shi | Asia Growth Partners

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Name	Shaolin Shi
Contact Information	shaolin.shi@nju.edu.cn
Language ability	English, Chinese
Province	Jiangsu

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Name

Shaolin Shi

Contact Information

shaolin.shi@nju.edu.cn

Language ability

English, Chinese

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Medical School
Academic Background & Achievements	1986 - Bachelor's Degree: Xiamen University 1992 - Master's Degree: Fudan University 1997 - Doctoral Degree: Fudan University Discovered new mechanisms of Notch glycosylation regulation Revealed roles and mechanisms of microRNAs in podocyte physiology and pathology Identified key genes and their functions in glomerular podocytes
Work Experience	1997-2004 - University of Glasgow/Cyclacel Ltd and Albert Einstein College of Medicine - Postdoctoral Researcher 2005-2011 - Mount Sinai Icahn School of Medicine - Assistant Professor 2011-Present - Eastern Theater General Hospital (Jinling Hospital) - Chief Technician, National Clinical Research Center for Kidney Disease
Awards	National Science and Technology Progress Award (2020): Innovation and application of glomerulonephritis diagnosis and treatment strategies and key technologies Jiangsu Provincial Science and Technology Progress Award (2017): Research on podocyte injury mechanisms and clinical translation

University/Lab Affiliation and Title

Nanjing University

Faculty

Medical School

Academic Background & Achievements

1986 - Bachelor's Degree: Xiamen University
1992 - Master's Degree: Fudan University
1997 - Doctoral Degree: Fudan University
Discovered new mechanisms of Notch glycosylation regulation
Revealed roles and mechanisms of microRNAs in podocyte physiology and pathology
Identified key genes and their functions in glomerular podocytes

Work Experience

1997-2004 - University of Glasgow/Cyclacel Ltd and Albert Einstein College of Medicine - Postdoctoral Researcher
2005-2011 - Mount Sinai Icahn School of Medicine - Assistant Professor
2011-Present - Eastern Theater General Hospital (Jinling Hospital) - Chief Technician, National Clinical Research Center for Kidney Disease

Awards

National Science and Technology Progress Award (2020): Innovation and application of glomerulonephritis diagnosis and treatment strategies and key technologies
Jiangsu Provincial Science and Technology Progress Award (2017): Research on podocyte injury mechanisms and clinical translation

Areas of Focus	Molecular mechanisms and therapeutic target gene identification in diabetic nephropathy, FSGS, and various glomerulonephritis
Publications	Glucocorticoids Inhibit EGFR Signaling Activation in Podocytes in Anti-GBM Crescentic Glomerulonephritis, Wu X, Ren L, Yang Q, Song H, Tang Q, Zhang M, Zhang J, Tang Z, Shi S, 2022 A novel approach to identify the mechanism of miR-145-5p toxicity to podocytes based on the essential genes targeting analysis, Zhang S, Wu J, Zhu X, Song H, Ren L, Tang Q, Xu X, Liu C, Zhang J, Hu W, Liu Z, Shi S, 2021 MiR-30 family prevents uPAR-ITGB3 signaling activation through calcineurin-NFATC pathway to protect podocytes, Lang Y, Zhao Y, Zheng C, Lu Y, Wu J, Zhu X, Zhang M, Yang F, Xu X, Shi S, Liu Z, 2019 Genome-wide identification of genes essential for podocyte cytoskeletons based on single-cell RNA sequencing, Lu Y, Ye Y, Bao W, Yang Q, Wang J, Liu Z, Shi S, 2017 Single-cell RNA-sequence analysis of mouse glomerular mesangial cells uncovers mesangial cell essential genes, Lu Y, Ye Y, Yang Q, Shi S, 2017 Toll-like Receptor 9 Can be Activated by Endogenous Mitochondrial DNA to Induce Podocyte Apoptosis, Bao W, Xia H, Liang Y, Ye Y, Lu Y, Xu X, Duan A, He J, Chen Z, Wu Y, Wang X, Zheng C, Liu Z, Shi S, 2016 MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes, Wu J, Zheng C, Wang X, Yun S, Zhao Y, Liu L, Lu Y, Ye Y, Zhu X, Zhang C, Shi S, Liu Z, 2015 Plasma microRNA-186 and proteinuria in focal segmental glomerulosclerosis, Zhang C, Zhang W, Chen H, Liu C, Wu J, Shi S, Liu Z*, 2015

Areas of Focus

Molecular mechanisms and therapeutic target gene identification in diabetic nephropathy, FSGS, and various glomerulonephritis

Publications

Glucocorticoids Inhibit EGFR Signaling Activation in Podocytes in Anti-GBM Crescentic Glomerulonephritis, Wu X, Ren L, Yang Q, Song H, Tang Q, Zhang M, Zhang J, Tang Z*, Shi S*, 2022
A novel approach to identify the mechanism of miR-145-5p toxicity to podocytes based on the essential genes targeting analysis, Zhang S, Wu J, Zhu X, Song H, Ren L, Tang Q, Xu X, Liu C, Zhang J, Hu W, Liu Z*, Shi S*, 2021
MiR-30 family prevents uPAR-ITGB3 signaling activation through calcineurin-NFATC pathway to protect podocytes, Lang Y, Zhao Y, Zheng C, Lu Y, Wu J, Zhu X, Zhang M, Yang F, Xu X, Shi S*, Liu Z*, 2019
Genome-wide identification of genes essential for podocyte cytoskeletons based on single-cell RNA sequencing, Lu Y, Ye Y, Bao W, Yang Q, Wang J, Liu Z, Shi S*, 2017
Single-cell RNA-sequence analysis of mouse glomerular mesangial cells uncovers mesangial cell essential genes, Lu Y, Ye Y, Yang Q, Shi S*, 2017
Toll-like Receptor 9 Can be Activated by Endogenous Mitochondrial DNA to Induce Podocyte Apoptosis, Bao W, Xia H, Liang Y, Ye Y, Lu Y, Xu X, Duan A, He J, Chen Z, Wu Y, Wang X, Zheng C, Liu Z, Shi S*, 2016
MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes, Wu J, Zheng C, Wang X, Yun S, Zhao Y, Liu L, Lu Y, Ye Y, Zhu X, Zhang C, Shi S*, Liu Z*, 2015
Plasma microRNA-186 and proteinuria in focal segmental glomerulosclerosis, Zhang C, Zhang W, Chen H, Liu C, Wu J, Shi S*, Liu Z*, 2015

Diabetic Nephropathy Fsgs Glomerulonephritis Molecular Mechanisms Therapeutic Targets Podocytes Mesangial Cells Endothelial Cells Bioinformatics Gene Knockout

Min Zhao - Wuhan University

Yueying Li - University of Chinese Academy of Sciences

Hongxing Lei - University of Chinese Academy of Sciences

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