Professor | Weidong Gan | Asia Growth Partners

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Name	Weidong Gan
Contact Information	gwd@nju.edu.cn
Language ability	Chinese, English
Province	Jiangsu

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Name

Weidong Gan

Contact Information

gwd@nju.edu.cn

Language ability

Chinese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Medical School
Work Experience	2003/10-2009/09 - Nanjing University Medical School Affiliated Drum Tower Hospital - Associate Chief Physician 2009/10-present - Nanjing University Medical School Affiliated Drum Tower Hospital - Chief Physician 2011/10-2011/12 - University of Pittsburgh Medical Center - Visiting Scholar
Awards	Nanjing Medical New Technology Introduction Award (First Prize): Application of separation and fusion probes in gene-level diagnosis of TFE3 gene-related tumors Jiangsu Medical New Technology Introduction Award (Second Prize): Fluorescence in situ hybridization polyclonal separation probe diagnosis of Xp11.2 translocation renal cell carcinoma Jiangsu Province Education and Research Achievement Award (Research Category) (Third Prize): Construction and clinical application of Xp11.2 translocation/TFE3 gene fusion-related renal cell carcinoma diagnosis system

University/Lab Affiliation and Title

Nanjing University

Faculty

Medical School

Work Experience

2003/10-2009/09 - Nanjing University Medical School Affiliated Drum Tower Hospital - Associate Chief Physician
2009/10-present - Nanjing University Medical School Affiliated Drum Tower Hospital - Chief Physician
2011/10-2011/12 - University of Pittsburgh Medical Center - Visiting Scholar

Awards

Nanjing Medical New Technology Introduction Award (First Prize): Application of separation and fusion probes in gene-level diagnosis of TFE3 gene-related tumors
Jiangsu Medical New Technology Introduction Award (Second Prize): Fluorescence in situ hybridization polyclonal separation probe diagnosis of Xp11.2 translocation renal cell carcinoma
Jiangsu Province Education and Research Achievement Award (Research Category) (Third Prize): Construction and clinical application of Xp11.2 translocation/TFE3 gene fusion-related renal cell carcinoma diagnosis system

Areas of Focus	Clinical and basic research of urological tumors
Publications	PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma, Bo Wang, Xiaoqin Yin, Weidong Gan, Fan Pan, Shiyuan Li, Zou Xiang, Xiaodong Han, Dongmei Li, 2021 Estradiol Increases Risk of Topoisomerase Ⅱβ-mediated DNA Strand Breaks to Initiate Xp11.2 Translocation Renal Cell Carcinoma, Qiancheng Shi, Ning Liu, Lei Yang, Yi Chen, Yanwen Lu, Hongqian Guo, Xiaodong Han, Dongmei Li, Weidong Gan, 2021 NONO-TFE3 fusion promotes aerobic glycolysis and angiogenesis by targeting HIF1A in NONO-TFE3 translocation renal cell carcinoma, Yi Chen, Lei Yang, Ning Liu, Qiancheng Shi, Xiaoqin Yin, Xiaodong Han, Weidong Gan, Dongmei Li, 2021 NRF-1 directly regulates TFE3 and promotes the proliferation of renal cancer cells, Wenyuan Zhuang, Xiang Dong, Bo Wang, Ning Liu, Hongqian Guo, Chunni Zhang, Weidong Gan, 2021 Low expression of TRAF3IP2-AS1 promotes progression of NONO-TFE3 translocation renal cell carcinoma by stimulating N 6-methyladenosine of PARP1 mRNA and downregulating PTEN, Lei Yang, Yi Chen, Ning Liu, QianCheng Shi, Xiaodong Han, Weidong Gan, Dongmei Li, 2021 A new risk-scoring system to predict Xp11.2 translocation renal cell carcinoma in adults, Qiancheng Shi, Ning Liu, Yiqi Zhu, Feng Qu, Linfeng Xu, Xiaogong Li, Gutian Zhang, Hongqian Guo, Dongmei Li, Weidong Gan, 2021 Molecular Heterogeneity of Xp11.2 Translocation Renal Cell Carcinoma: The Correlation Between Split Signal Pattern in FISH and Prognosis, Yiqi Zhu, Xiaohong Pu, Xiang Dong, Changwei Ji, Hongqian Guo, Dongmei Li, Xiaozhi Zhao, Weidong Gan, 2021 The positive regulation loop between NRF1 and NONO-TFE3 fusion promotes phase separation and aggregation of NONO-TFE3 in NONO-TFE3 tRCC, Bo Wang, Weidong Gan, Xiaodong Han, Ning Liu, Tan Ma, Dongmei Li, 2021 Invention Patent: Fluorescence in situ hybridization polyclonal separation probe for renal cancer and its kit application, Weidong Gan Invention Patent: Gene probe for alveolar soft part sarcoma and its kit application, Weidong Gan

Areas of Focus

Clinical and basic research of urological tumors

Publications

PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma, Bo Wang, Xiaoqin Yin, Weidong Gan*, Fan Pan, Shiyuan Li, Zou Xiang, Xiaodong Han, Dongmei Li, 2021
Estradiol Increases Risk of Topoisomerase Ⅱβ-mediated DNA Strand Breaks to Initiate Xp11.2 Translocation Renal Cell Carcinoma, Qiancheng Shi, Ning Liu, Lei Yang, Yi Chen, Yanwen Lu, Hongqian Guo, Xiaodong Han, Dongmei Li*, Weidong Gan*, 2021
NONO-TFE3 fusion promotes aerobic glycolysis and angiogenesis by targeting HIF1A in NONO-TFE3 translocation renal cell carcinoma, Yi Chen, Lei Yang, Ning Liu, Qiancheng Shi, Xiaoqin Yin, Xiaodong Han, Weidong Gan, Dongmei Li, 2021
NRF-1 directly regulates TFE3 and promotes the proliferation of renal cancer cells, Wenyuan Zhuang, Xiang Dong, Bo Wang, Ning Liu, Hongqian Guo, Chunni Zhang*, Weidong Gan*, 2021
Low expression of TRAF3IP2-AS1 promotes progression of NONO-TFE3 translocation renal cell carcinoma by stimulating N 6-methyladenosine of PARP1 mRNA and downregulating PTEN, Lei Yang, Yi Chen, Ning Liu, QianCheng Shi, Xiaodong Han, Weidong Gan*, Dongmei Li*, 2021
A new risk-scoring system to predict Xp11.2 translocation renal cell carcinoma in adults, Qiancheng Shi, Ning Liu, Yiqi Zhu, Feng Qu, Linfeng Xu, Xiaogong Li, Gutian Zhang, Hongqian Guo, Dongmei Li, Weidong Gan*, 2021
Molecular Heterogeneity of Xp11.2 Translocation Renal Cell Carcinoma: The Correlation Between Split Signal Pattern in FISH and Prognosis, Yiqi Zhu, Xiaohong Pu, Xiang Dong, Changwei Ji, Hongqian Guo, Dongmei Li, Xiaozhi Zhao, Weidong Gan*, 2021
The positive regulation loop between NRF1 and NONO-TFE3 fusion promotes phase separation and aggregation of NONO-TFE3 in NONO-TFE3 tRCC, Bo Wang, Weidong Gan*, Xiaodong Han, Ning Liu, Tan Ma, Dongmei Li, 2021
Invention Patent: Fluorescence in situ hybridization polyclonal separation probe for renal cancer and its kit application, Weidong Gan
Invention Patent: Gene probe for alveolar soft part sarcoma and its kit application, Weidong Gan

Urological Tumors Clinical Research Basic Research Xp11.2 Translocation Renal Cell Carcinoma Tfe3 Gene Diagnosis Molecular Level Patents Publications

Xianlong Zhou - Wuhan University

Jing Chen - Wuhan University

Hongxin Xu - Wuhan University

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