2014.07-2018.01 PhD in Biochemistry and Molecular Biology, Tongji University/Institute of Biophysics, Chinese Academy of Sciences
2007.09-2011.06 Master in Biomedical Science, East China Normal University/Shanghai Institute of Materia Medica, Chinese Academy of Sciences
2002.09-2006.06 Bachelor of Engineering in Food Engineering, Shihezi University
2018.02-present Tongji University Affiliated First Maternity and Infant Health Hospital - Assistant Researcher, Associate Researcher
2014.07-2018.01 Tongji University/Institute of Biophysics, Chinese Academy of Sciences - PhD Student
2012.07-2014.06 Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences - Assistant Researcher
2011.07-2012.06 WuXi AppTec - Researcher
2007.09-2011.06 East China Normal University/Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Master Student
Research
Somatic cell reprogramming mechanisms Application of pluripotent stem cells and clinical samples for in vitro simulation and regenerative medicine research of the female reproductive system
Comprehensive transcriptional atlas of human adenomyosis deciphered by the integration of single-cell RNA-sequencing and spatial transcriptomics, Chen T, Xu Y, Xu X, Wang J, Qiu Z, Yu Y, Jiang X, Shao W, Bai D, Wang M, Mei S, Cheng T, Wu L, Gao S, Che X, 2024
Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice, Shen J, Wu L, Shi X, Chen G, Liu T, Xu F, Xu X, Kou X, Zhao Y, Wang H, Wang C, Gao S, Xu S, 2024
Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy, Xi C, Yan Z, Bai D, Zhang Y, Wang B, Han XX, Wu L, Shi X, Hu Z, Tang M, Su Z, Liu Y, Liu B, Yin J, Wang H, Li X, Zhang Y, Gao S, Liu W, 2024
Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency, Liu D, Guan X, Liu W, Jia Y, Zhou H, Xi C, Zhao M, Fang Y, Wu L, Li K, 2023
Modeling human pregastrulation development by 3D culture of blastoids generated from primed-to-naïve transitioning intermediates, Tu Z, Bi Y, Zhu X, Liu W, Hu J, Wu L, Mao T, Zhou J, Wang H, Wang H, Gao S, Wang Y, 2023
Remodeling of H3K9me3 during the pluripotent to totipotent-like state transition, Li H, Sun J, Dong Y, Huang Y, Wu L, Xi C, Su Z, Xiao Y, Zhang C, Liang Y, Li Y, Lin Z, Shen L, Zuo Y, Abudureheman A, Yin J, Wang H, Kong X, Le R, Gao S, Zhang Y, 2023
LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei, Zhu J, Chen K, Sun YH, Ye W, Liu J, Zhang D, Su N, Wu L, Kou X, Zhao Y, Wang H, Gao S, Kang L, 2023
Mettl14-driven senescence-associated secretory phenotype facilitates somatic cell reprogramming, Xi C, Sun J, Xu X, Wu Y, Kou X, Zhao Y, Shen J, Dong Y, Chen K, Su Z, Liu D, Ye W, Liu Y, Zhang R, Xu Y, Wang H, Hao L, Wu L, Gao S, 2022
Enhancement of Xrcc1-mediated base excision repair improves the genetic stability and pluripotency of iPSCs, Zhao K, Sun X, Zheng C, Wang M, Xu Z, Wang M, Chen J, Guo M, Le R, Wu L, Wang Y, Kou X, Zhao Y, Yin J, Wang H, Mao Z, Gao S, Gao S, 2022
Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress, Wu L, He S, Ye W, Shen J, Zhao K, Zhang Y, Zhang R, Wei J, Cao S, Chen K, Le R, Xi C, Kou X, Zhao Y, Wang H, Kang L, Gao S, 2021
The SIRT6 activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells, Chen Y, Chen J, Sun X, Yu J, Qian Z, Wu L, Xu X, Wan X, Jiang Y, Zhang J, Gao S, Mao Z, 2020
Accurate annotation of accessible chromatin in mouse and human primordial germ cells, Li J, Shen S, Chen J, Liu W, Li X, Zhu Q, Wang B, Chen X, Wu L, Wang M, Gu L, Wang H, Yin J, Jiang C, Gao S, 2018
Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and mitigating Cell Hyperproliferation, Wu L, Wu Y, Peng B, Hou Z, Dong Y, Chen K, Guo M, Li H, Chen X, Kou X, Zhao Y, Bi Y, Wang Y, Wang H, Le R, Kang L, Gao S, 2017
Functional Role of Histidine in the Conserved His-x-Asp Motif in the Catalytic Core of Protein Kinases, Zhang L, Wang JC, Hou L, Cao PR, Wu L, Zhang QS, Yang HY, Zang Y, Ding JP, Li J, 2015
Screening of AMPK interacted proteins by yeast two hybrid system, Wu L, Yang C, Deng S, Zhou Y, Qian M, Zang Y, 2012
5'-AMP-activated protein kinase (AMPK) regulates progesterone receptor transcriptional activity in breast cancer cells, Wu L, Huang XJ, Yang CH, Deng SS, Qian M, Zang Y, Li J, 2011
