Professor | Ru Zhang | Asia Growth Partners

Name	Ru Zhang
Contact Information	ru.zhang@tongji.edu.cn
Language ability	English, Chinese, German
Province	Shanghai

Name

Ru Zhang

Contact Information

ru.zhang@tongji.edu.cn

Language ability

English, Chinese, German

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	1996 - Bachelor of Medicine: Shanghai Medical University (now Fudan University Medical College) 1999 - Master of Medicine: Shanghai Medical University (now Fudan University Medical College) 2003 - PhD in Biology: University of Giessen, Germany Selected for Shanghai Pujiang Talent Program in 2008
Work Experience	2004-2007 - Max Planck Institute for Biochemistry, Germany: Postdoctoral Researcher 2008-Present - Tongji University, School of Life Sciences and Technology, Shanghai: Associate Professor

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

1996 - Bachelor of Medicine: Shanghai Medical University (now Fudan University Medical College)
1999 - Master of Medicine: Shanghai Medical University (now Fudan University Medical College)
2003 - PhD in Biology: University of Giessen, Germany
Selected for Shanghai Pujiang Talent Program in 2008

Work Experience

2004-2007 - Max Planck Institute for Biochemistry, Germany: Postdoctoral Researcher
2008-Present - Tongji University, School of Life Sciences and Technology, Shanghai: Associate Professor

Areas of Focus	Cell signaling research, aging and Alzheimer's disease pathogenesis, and related innovative drug discovery Stem cell fate regulation and related small molecule drug discovery
Publications	Neonatal cortical astrocytes possess intrinsic potential in neuronal conversion in defined media, Zeng P, Hua QH, Gong JY, Shi CJ, Pi XP, Xie X, Zhang R, 2021 Development of Human in vitro Brain-blood Barrier Model from Induced Pluripotent Stem Cell-derived Endothelial Cells to Predict the in vivo Permeability of Drugs, Li Y, Sun X, Liu H, Huang L, Meng G, Ding Y, Su W, Lu J, Gong S, Terstappen GC, Zhang R, Zhang W, 2019 Donepezil, a drug for Alzheimer's disease, promotes oligodendrocyte generation and remyelination, Cui X, Guo YE, Fang JH, Shi CJ, Suo N, Zhang R, Xie X, 2019 One-step generation of mice carrying a conditional allele together with an HA-tag insertion for the delta opioid receptor, Su D, Wang M, Ye C, Fang J, Duan Y, Zhang Z, Hua Q, Shi C, Zhang L, Zhang R, Xie X, 2017 CXCR4 activation promotes differentiation of human embryonic stem cells to neural stem cells, Zhang L, Hua Q, Tang K, Shi C, Xie X, Zhang R, 2016 Methuselah regulates longevity via dTOR: a pathway revealed by small-molecule ligands, Wang, Junjie; Wang, Zhilong; Zhang, Zhenghong; Hua, Qiuhong; Wang, Min; Shi, Changjie; Xue, Lei; Zhang, Ru; Xie, Xin, 2015 Identification of a novel small-molecule agonist for human G protein-coupled receptor 3, Ye C, Zhang Z, Wang Z, Hua Q, Zhang R, Xie X, 2014 Proliferation rate of somatic cells affects reprogramming efficiency, Yongyu Xu, Xiaoyuan Wei, Min Wang, Ru Zhang, Yanbin Fu, Mingzhe Xing, Qiuhong Hua, Xin Xie, 2013 iPSCs and small molecules: a reciprocal effort towards better approaches for drug discovery, Ru Zhang, Lihong Zhang, Xin Xie, 2013 Novel Object Recognition as a Facile Behavior Test for Evaluating Drug Effects in A PP/PS1 Alzheimer’s Disease Mouse Model, Ru Zhang, Guizhen Xue, Shaodeng Wang, Lihong Zhang, Changjie Shi, Xin Xie, 2012 Tools for GPCR Drug Discovery, Ru Zhang, Xin Xie, 2012 Stress-mediated p38 activation promotes somatic cell reprogramming, Xinxiu Xu, Quan Wang, Yuan Long, Ru Zhang, Xiaoyuan Wei, Mingzhe Xing, Haifeng Gu, Xin Xie, 2012 Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach, Koch H, Zhang R, Verdoodt B, Bailey A, Zhang CD, Yates 3rd JR, Menssen A, Hermeking H, 2007 CTCF binding and higher order chromatin structure of the H19 locus are maintained in mitotic chromatin, Burke LJ, Zhang R, Bartkuhn M, Tiwari VK, Tavoosidana G, Kurukuti S, Weth C, Leers J, Galjart N, Ohlsson R, Renkawitz R, 2005 Dynamic association of the mammalian insulator protein CTCF with centrosomes and the midbody, Zhang R, Burke LJ, Rasko J, Lobanenkov V, Renkawitz R, 2004

Areas of Focus

Cell signaling research, aging and Alzheimer's disease pathogenesis, and related innovative drug discovery
Stem cell fate regulation and related small molecule drug discovery

Publications

Neonatal cortical astrocytes possess intrinsic potential in neuronal conversion in defined media, Zeng P, Hua QH, Gong JY, Shi CJ, Pi XP, Xie X, Zhang R, 2021
Development of Human in vitro Brain-blood Barrier Model from Induced Pluripotent Stem Cell-derived Endothelial Cells to Predict the in vivo Permeability of Drugs, Li Y, Sun X, Liu H, Huang L, Meng G, Ding Y, Su W, Lu J, Gong S, Terstappen GC, Zhang R, Zhang W, 2019
Donepezil, a drug for Alzheimer's disease, promotes oligodendrocyte generation and remyelination, Cui X, Guo YE, Fang JH, Shi CJ, Suo N, Zhang R, Xie X, 2019
One-step generation of mice carrying a conditional allele together with an HA-tag insertion for the delta opioid receptor, Su D, Wang M, Ye C, Fang J, Duan Y, Zhang Z, Hua Q, Shi C, Zhang L, Zhang R, Xie X, 2017
CXCR4 activation promotes differentiation of human embryonic stem cells to neural stem cells, Zhang L, Hua Q, Tang K, Shi C, Xie X, Zhang R, 2016
Methuselah regulates longevity via dTOR: a pathway revealed by small-molecule ligands, Wang, Junjie; Wang, Zhilong; Zhang, Zhenghong; Hua, Qiuhong; Wang, Min; Shi, Changjie; Xue, Lei; Zhang, Ru; Xie, Xin, 2015
Identification of a novel small-molecule agonist for human G protein-coupled receptor 3, Ye C, Zhang Z, Wang Z, Hua Q, Zhang R, Xie X, 2014
Proliferation rate of somatic cells affects reprogramming efficiency, Yongyu Xu, Xiaoyuan Wei, Min Wang, Ru Zhang, Yanbin Fu, Mingzhe Xing, Qiuhong Hua, Xin Xie, 2013
iPSCs and small molecules: a reciprocal effort towards better approaches for drug discovery, Ru Zhang, Lihong Zhang, Xin Xie, 2013
Novel Object Recognition as a Facile Behavior Test for Evaluating Drug Effects in A PP/PS1 Alzheimer’s Disease Mouse Model, Ru Zhang, Guizhen Xue, Shaodeng Wang, Lihong Zhang, Changjie Shi, Xin Xie, 2012
Tools for GPCR Drug Discovery, Ru Zhang, Xin Xie, 2012
Stress-mediated p38 activation promotes somatic cell reprogramming, Xinxiu Xu, Quan Wang, Yuan Long, Ru Zhang, Xiaoyuan Wei, Mingzhe Xing, Haifeng Gu, Xin Xie, 2012
Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach, Koch H, Zhang R, Verdoodt B, Bailey A, Zhang CD, Yates 3rd JR, Menssen A, Hermeking H, 2007
CTCF binding and higher order chromatin structure of the H19 locus are maintained in mitotic chromatin, Burke LJ, Zhang R, Bartkuhn M, Tiwari VK, Tavoosidana G, Kurukuti S, Weth C, Leers J, Galjart N, Ohlsson R, Renkawitz R, 2005
Dynamic association of the mammalian insulator protein CTCF with centrosomes and the midbody, Zhang R, Burke LJ, Rasko J, Lobanenkov V, Renkawitz R, 2004

Cell Signaling Aging Alzheimer'S Disease Drug Discovery Gpcr Signaling Pathway Mitochondrial Damage Neurodegenerative Diseases High-Throughput Screening Induced Pluripotent Stem Cells Small Molecules

Yujun Hou - Tongji University

Hongbing Wang - Tongji University

Hongbing Wang - Tongji University

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