Areas of Focus
- Tissue Engineering and Periodontal Regenerative Therapy
- Relationship between Periodontal Disease and Systemic Diseases
- Implant Restoration Treatment of Periodontal Disease
Work Experience
- Former - Dean: Fujian Medical University School of Stomatology
- Former - Dean: Graduate School of Fujian Medical University
- Former - President: Fujian Stomatological Association
- Former - Chairman: Periodontology Committee of Jiangsu Stomatological Association
- Current - Deputy Director: Affiliated Stomatological Hospital of Nanjing University Medical School
- Current - Doctoral Supervisor: Nanjing University Medical School
- Current - Chairman: Periodontology Committee of Chinese Stomatological Association
- Current - Vice President: Jiangsu Stomatological Association
Academic Background & Achievements
- 1985 - Bachelor's Degree in Medicine: Zunyi Medical College
- 1993 - Doctorate in Medicine: Peking University School of Stomatology
- 1998 - Visiting Scholar: University of Queensland, Australia
- Supervised 28 PhD graduates and 55 Master's graduates
- Currently supervising 4 postdoctoral researchers, 6 PhD students, and 6 Master's students
Publications
- Periodontitis may induce gut microbiota dysbiosis via salivary microbiota, Bao J, Li L, Zhang Y, Wang M, Chen F, Ge S, Chen B*, Yan F*, 2022
- Periodontitis-related salivary microbiota aggravates Alzheimer's disease via gut-brain axis crosstalk, Lu J, Zhang S, Huang Y, Qian J, Tan B, Qian X, Zhuang J, Zou X, Li Y*, Yan F*, 2022
- Periodontitis salivary microbiota worsens colitis, Qian J, Lu J, Huang Y, Wang M, Chen B, Bao J, Wang L, Cui D, Luo B, Yan F*, 2021
- Periodontitis may impair the homeostasis of systemic bone through regulation of gut microbiota in ApoE-/- mice, Li L, Wang M, Bao J, Wang N, Huang Y, He S, Chen B*, Yan F*, 2022
- Diaryl urea derivative molecule inhibits cariogenic Streptococcus mutans by affecting exopolysaccharide synthesis, stress response and nitrogen metabolism, Liao Y, Zhang M, Lin X*, Yan F*, 2022
- Accelerated alveolar bone loss in a mouse model of inflammatory bowel disease and its relationship with intestinal inflammation, Qiao D, Chen R, Li L, Zhu F, Zhang Y*, Yan F*, 2022
- Salivary microbiota of periodontitis aggravates bone loss in ovariectomized rats, Wang N, Zheng L, Qian J, Wang M, Li L, Huang Y, Zhang Q, Li Y*, Yan F*, 2022
- Novel urea derivative-loaded PLGA nanoparticles to inhibit caries-associated Streptococcus mutans, Zhang M, Liao Y, Tong X*, Yan F*, 2022
- Prevalence of early childhood caries in three regions of China: a cross-sectional study, Liao Y, Zhou C, Zhang Q, Wang X, Yan F*, Xing X*, 2022
- Ultrathin 2D Titanium Carbide MXene (Ti3C2Tx) nanoflakes activate WNT/HIF-1alpha-mediated metabolism reprogramming for periodontal regeneration, Cui D, Kong N, Ding L, Guo Y*, Yang W*, Yan F*, 2021
- L-cysteine-modified chiral gold nanoparticles promote periodontal tissue regeneration, Zhang S, Zhou H, Kong N, Wang Z, Fu H, Zhang Y, Xiao Y*, Yang W*, Yan F*, 2021
- Gut microbiota may mediate the influence of periodontitis on prediabetes, Li L, Bao J, Chang Y, Wang M, Chen B*, Yan F*, 2021
- Gold nanoparticles promote the bone regeneration of periodontal ligament stem cell sheets through activation of autophagy, Zhang Y, Wang P, Wang Y, Li J, Qiao D, Chen R, Yang W, Yan F*, 2021
- Inhibiting PHD2 in human periodontal ligament cells via lentiviral vector-mediated RNA interference facilitates cell osteogenic differentiation and periodontal repair, Cui D, Chen C, Luo B, Yan F*, 2021
- Characteristics of a bacteriophage, vB_Kox_ZX8, isolated from clinical klebsiella oxytoca and its therapeutic effect on mice bacteremia, Li P, Zhang Y, Yan F*, Zhou X*, 2021
- Gold nanoclusters exert bactericidal activity and enhance phagocytosis of macrophage mediated killing of Fusobacterium nucleatum, Chen R, Qiao D, Wang P, Li L, Zhang Y*, Yan F*, 2021
- Active smoking induces aberrations in digestive tract microbiota of rats, Wang X, Ye P, Fang L, Ge S, Huang F, Polverini PJ, Heng W, Zheng L, Hu Q*, Yan F*, Wang W*, 2021
- Epigenetic changes caused by diabetes and their potential role in the development of periodontitis, Li Y, Du Z, Xie X, Zhang Y, Liu H, Zhou Z, Zhao J, Lee RS, Xiao Y, Ivanoviski S, Yan F*, 2021
- The association between periodontitis and inflammatory bowel disease: a systematic review and Meta-analysis, Zhang Y, Qiao D, Chen R, Zhu F, Gong J, Yan F*, 2021
- Gold nanoparticles combined human β-defensin 3 gene-modified human periodontal ligament cells alleviate periodontal destruction via the p38 MAPK pathway, Li L, Zhang Y, Wang M, Zhou J, Zhang Q, Yang W*, Li Y*, Yan F*, 2021
- Periodontitis deteriorates cognitive function and impairs neurons and glia in a mouse model of Alzheimer's disease, Qian X, Zhang S, Duan L, Yang F, Zhang K, Yan F*, Ge S*, 2021
- Non-surgical periodontal treatment restored the gut microbiota and intestinal barrier in Apolipoprotein E-/- mice with periodontitis, Huang Y, Liao Y, Luo B, Li L, Zhang Y, Yan F*, 2020
- Human β-defensin 3 gene modification promotes the osteogenic differentiation of human periodontal ligament cells and bone repair in periodontitis, Li L, Jiang H, Chen R, Zhou J, Xiao Y, Zhang Y*, Yan F*, 2020
- Poor oral health conditions and cognitive decline: Studies in humans and rats, Zhang S, Yang F, Wang Z, Qian X, Ji Y, Gong L, Ge S*, Yan F*, 2020
- Gold nanoparticles modulate the crosstalk between macrophages and periodontal ligament cells for periodontitis treatment, Ni C, Zhou J, Kong N, Bian T, Zhang Y, Huang X, Xiao Y*, Yang W*, Yan F*, 2019
- Lithium-calcium-silicate bioceramics stimulating cementogenic/osteogenic differentiation of periodontal ligament cells and periodontal regeneration, Zhang Q, Chen L, Chen B, Chen C, Chang J, Xiao Y, Wu C, Yan F*, 2019
- Macrophage polarization in periodontal ligament stem cells enhanced periodontal regeneration, Liu J, Chen B, Bao J, Zhang Y, Lei L*, Yan F*, 2019
- Human β-defensin 3-combined gold nanoparticles for enhancement of osteogenic differentiation of human periodontal ligament cells in inflammatory microenvironments, Zhou J, Zhang Y, Li L, Fu H, Yang W, Yan F*
Awards
- 2021 - Nanjing University Excellent Doctoral Dissertation: Zhang Shuang's research on chiral gold nanoparticles
- 2020 - Ministry of Education Science and Technology Progress Award (Second Prize): Research and promotion of key prevention and treatment technologies for periodontitis
- 2020 - Jiangsu Province New Technology Introduction Award (First Prize): Application of minimally invasive periodontal diagnosis and treatment technology
- 2010 - Fujian Province Science and Technology Progress Award (Second Prize): Research on the application of tissue engineering technology in the treatment of periodontal diseases
- 2009 - Fujian Province Teaching Achievement Award (Second Prize): Training of dental medicine talents based on the needs of Haixi construction
