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Zhang Aihua
zhaihua@njmu.edu.cn
Chinese, English
Jiangsu
Nanjing University
Medical School
  • National Outstanding Youth Science Fund Recipient
  • Expert enjoying special government allowances from the State Council
  • Leading Talent in Science and Technology Innovation by the Ministry of Science and Technology
  • Jiangsu Province Distinguished Professor
  • First-level training object of Jiangsu Province '333 Project'
  • Deputy Director of the Children's Hospital Affiliated to Nanjing Medical University/Head of Nephrology
  • Director of the Key Laboratory of Major Pediatric Diseases Research in Jiangsu Province
  • Director of the Pediatric Research Institute of Nanjing Medical University
  • First Prize of Medical New Technology Introduction Award of Jiangsu Provincial Health and Family Planning Commission (2021): Application of Minigene Technology in Gene Diagnosis of Rare Genetic Diseases in Children
  • First Prize of Medical New Technology Introduction Award of Jiangsu Province (2018): Application of Next-Generation Sequencing Technology in the Diagnosis of Rare Genetic Diseases in Children
  • Second Prize of National Women's and Children's Health Science and Technology Award (2017): Study on the Role of Oxidative Stress in the Pathogenesis and Early Intervention of Chronic Kidney Disease in Children
  • Second Prize of Jiangsu Medical Science and Technology Award (2016): Study on the Key Mechanisms and Early Diagnosis and Treatment of Chronic Kidney Disease in Children
  • Second Prize of Jiangsu Provincial Science and Technology Award (2014): Study on the Role and Intervention of Oxidative Stress in the Occurrence and Progression of Chronic Kidney Disease
  • First Prize of the Ministry of Education Natural Science Award (2014): Study on the Key Mechanisms and Diagnostic Markers of Chronic Kidney Disease Progression
  • Song Qingling Pediatric Medicine Award (2013): Study on the Role of Oxidative Stress in the Pathogenesis and Early Intervention of Chronic Kidney Disease in Children
  • Third Prize of Jiangsu Provincial Science and Technology Progress Award (2010): Study on the Cellular and Molecular Mechanisms and Intervention of Renal Fibrosis
  • Second Prize of Jiangsu Medical Science and Technology Award (2010): Study on the Role of JNK Signaling Pathway Activation in the Pathogenesis and Early Diagnosis of Chronic Kidney Disease in Children
  • Third Prize of Jiangsu Provincial Science and Technology Progress Award (2009): Study on the Role of Oxidative Stress-Mediated MAPK Signaling Pathway Activation in Chronic Kidney Disease in Children
Pediatric Nephrology
  • Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI, Corresponding Author, 2020
  • Response to comment on 'Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI', Corresponding Author, 2021
  • Dimethyl fumarate prevents ferroptosis to attenuate acute kidney injury by acting on NRF2, Corresponding Author, 2021
  • Reduced Lon protease 1 expression in podocytes contributes to the pathogenesis of podocytopathy, Corresponding Author, 2021
  • MicroRNA-214 promotes chronic kidney disease by disrupting mitochondrial oxidative phosphorylation, Corresponding Author, 2019
  • Functional Characterization of PHEX Gene Variants in Children With X-Linked Hypophosphatemic Rickets Shows No Evidence of Genotype-Phenotype Correlation, Corresponding Author, 2020
  • Immune Regulator Retinoic Acid-Inducible Gene I (RIG-I) in the Pathogenesis of Cardiovascular Disease, Corresponding Author, 2022
  • Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation, Corresponding Author, 2022
  • Clinical Potential of Hypoxia Inducible Factors Prolyl Hydroxylase Inhibitors in Treating Nonanemic Diseases, Corresponding Author, 2022
  • Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury, Corresponding Author, 2022
  • mPGES-2 blockade antagonizes β-cell senescence to ameliorate diabetes by acting on NR4A1, Corresponding Author, 2022
  • Computational Systems Pharmacology, Molecular Docking and Experiments Reveal the Protective Mechanism of Li-Da-Qian Mixture in the Treatment of Glomerulonephritis, Corresponding Author, 2021
  • Gasdermin E Deletion Attenuates Ureteral Obstruction- and 5/6 Nephrectomy-Induced Renal Fibrosis and Kidney Dysfunction, Corresponding Author, 2021
  • Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS, Corresponding Author, 2021
  • SIRT1 Alleviates Aldosterone-Induced Podocyte Injury by Suppressing Mitochondrial Dysfunction and NLRP3 Inflammasome Activation, Corresponding Author, 2021
  • Blocking AURKA with MK-5108 attenuates renal fibrosis in chronic kidney disease, Corresponding Author, 2021
  • Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability, Corresponding Author, 2021
  • Clinical and Functional Characterization of Novel INSR Variants in Two Families With Severe Insulin Resistance Syndrome, Corresponding Author, 2021
  • Estrogen-Related Receptor γ Agonist DY131 Ameliorates Lipopolysaccharide-Induced Acute Liver Injury, Corresponding Author, 2021
  • The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction, Corresponding Author, 2021
  • Multi-centre study of the clinical features and gene variant spectrum of Gitelman syndrome in Chinese children, Corresponding Author, 2021
  • Gasdermin E deficiency attenuates acute kidney injury by inhibiting pyroptosis and inflammation, Corresponding Author, 2021
  • Cilomilast Ameliorates Renal Tubulointerstitial Fibrosis by Inhibiting the TGF-β1-Smad2/3 Signaling Pathway, Corresponding Author, 2021
  • Celastrol inhibits intestinal lipid absorption by reprofiling the gut microbiota to attenuate high-fat diet-induced obesity, Corresponding Author, 2021
  • Targeting microsomal prostaglandin E synthase 1 to develop drugs treating the inflammatory diseases, Corresponding Author, 2021
  • The emerging role of MEIS1 in cell proliferation and differentiation, Corresponding Author, 2020
  • Mitochondrial Dysfunction and the AKI to CKD Transition, Corresponding Author, 2020
  • miR-214 Protects Against Uric Acid-Induced Endothelial Cell Apoptosis, Corresponding Author, 2020
  • LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments, Corresponding Author, 2020
  • New Criterion to Evaluate Acute-on-Chronic Kidney Injury Based on the Creatinine Reference Change, Corresponding Author, 2020
  • Inhibition of ROCK2 alleviates renal fibrosis and the metabolic disorders in the proximal tubular epithelial cells, Corresponding Author, 2020
  • Chinese
Chronic Kidney Disease Acute Kidney Injury Pediatric Nephrology Mitochondrial Dysfunction Oxidative Stress Renal Fibrosis Gene Diagnosis Early Intervention Inflammation Cellular Mechanisms

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