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Zhang Aihua
Medical School
Nanjing University
Jiangsu
Language: Chinese, English
Chronic Kidney Disease
Acute Kidney Injury
Mitochondrial Metabolism
Renal Function
Pediatric Nephrology
Early Intervention
Kidney Disease Mechanisms
Nephrology Research
Kidney Injury
Renal Pathology
Areas of Focus
- Pediatric Nephrology
Academic Background & Achievements
- National Distinguished Young Scientist Fund recipient
- Expert enjoying special government allowances from the State Council
- Leading talent in science and technology innovation by the Ministry of Science and Technology
- Jiangsu Province Distinguished Professor
- First-level training object of Jiangsu Province '333 Project'
- Deputy Director of the Children's Hospital Affiliated to Nanjing Medical University/Head of Nephrology
- Director of the Key Laboratory of Major Pediatric Diseases Research in Jiangsu Province
- Director of the Pediatric Research Institute of Nanjing Medical University
Publications
- Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI, Zhang Aihua, 2020
- Response to comment on 'Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI', Zhang Aihua, 2021
- Dimethyl fumarate prevents ferroptosis to attenuate acute kidney injury by acting on NRF2, Zhang Aihua, 2021
- Reduced Lon protease 1 expression in podocytes contributes to the pathogenesis of podocytopathy, Zhang Aihua, 2021
- MicroRNA-214 promotes chronic kidney disease by disrupting mitochondrial oxidative phosphorylation, Zhang Aihua, 2019
- Functional Characterization of PHEX Gene Variants in Children With X-Linked Hypophosphatemic Rickets Shows No Evidence of Genotype-Phenotype Correlation, Zhang Aihua, 2020
- Immune Regulator Retinoic Acid-Inducible Gene I (RIG-I) in the Pathogenesis of Cardiovascular Disease, Zhang Aihua, 2022
- Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation, Zhang Aihua, 2022
- Clinical Potential of Hypoxia Inducible Factors Prolyl Hydroxylase Inhibitors in Treating Nonanemic Diseases, Zhang Aihua, 2022
- Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury, Zhang Aihua, 2022
- mPGES-2 blockade antagonizes β-cell senescence to ameliorate diabetes by acting on NR4A1, Zhang Aihua, 2022
- Computational Systems Pharmacology, Molecular Docking and Experiments Reveal the Protective Mechanism of Li-Da-Qian Mixture in the Treatment of Glomerulonephritis, Zhang Aihua, 2021
- Gasdermin E Deletion Attenuates Ureteral Obstruction- and 5/6 Nephrectomy-Induced Renal Fibrosis and Kidney Dysfunction, Zhang Aihua, 2021
- Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS, Zhang Aihua, 2021
- SIRT1 Alleviates Aldosterone-Induced Podocyte Injury by Suppressing Mitochondrial Dysfunction and NLRP3 Inflammasome Activation, Zhang Aihua, 2021
- Blocking AURKA with MK-5108 attenuates renal fibrosis in chronic kidney disease, Zhang Aihua, 2021
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability, Zhang Aihua, 2021
- Clinical and Functional Characterization of Novel INSR Variants in Two Families With Severe Insulin Resistance Syndrome, Zhang Aihua, 2021
- Estrogen-Related Receptor γ Agonist DY131 Ameliorates Lipopolysaccharide-Induced Acute Liver Injury, Zhang Aihua, 2021
- The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction, Zhang Aihua, 2021
- Multi-centre study of the clinical features and gene variant spectrum of Gitelman syndrome in Chinese children, Zhang Aihua, 2021
- Gasdermin E deficiency attenuates acute kidney injury by inhibiting pyroptosis and inflammation, Zhang Aihua, 2021
- Cilomilast Ameliorates Renal Tubulointerstitial Fibrosis by Inhibiting the TGF-β1-Smad2/3 Signaling Pathway, Zhang Aihua, 2021
- Celastrol inhibits intestinal lipid absorption by reprofiling the gut microbiota to attenuate high-fat diet-induced obesity, Zhang Aihua, 2021
- Targeting microsomal prostaglandin E synthase 1 to develop drugs treating the inflammatory diseases, Zhang Aihua, 2021
- The emerging role of MEIS1 in cell proliferation and differentiation, Zhang Aihua, 2020
- Mitochondrial Dysfunction and the AKI to CKD Transition, Zhang Aihua, 2020
- miR-214 Protects Against Uric Acid-Induced Endothelial Cell Apoptosis, Zhang Aihua, 2020
- LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments, Zhang Aihua, 2020
- New Criterion to Evaluate Acute-on-Chronic Kidney Injury Based on the Creatinine Reference Change, Zhang Aihua, 2020
- Inhibition of ROCK2 alleviates renal fibrosis and the metabolic disorders in the proximal tubular epithelial cells, Zhang Aihua, 2020
- Chinese Society of Pediatric Nephrology and Chinese Medical Doctor Association of Pediatric Nephrology. Consensus recommendations for the care of children receiving chronic dialysis in association with the COVID-19 epidemic, Zhang Aihua, 2020
- IPDN-China investigators. IPDN-China promotes the development of pediatric dialysis in China, Zhang Aihua, 2020
- Splicing Characterization of CLCNKB Variants in Four Patients With Type III Bartter Syndrome, Zhang Aihua, 2020
- Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation, Zhang Aihua, 2020
- Ursodeoxycholic acid protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction through acting on ALDH1L2, Zhang Aihua, 2020
- Inhibition of PDE4/PDE4B improves renal function and ameliorates inflammation in cisplatin-induced acute kidney injury, Zhang Aihua, 2020
- MicroRNA-214 targets COX-2 to antagonize indoxyl sulfate (IS)-induced endothelial cell apoptosis, Zhang Aihua, 2020
- Activation of GSDMD contributes to acute kidney injury induced by cisplatin, Zhang Aihua, 2020
- Multicenter study of the clinical features and mutation gene spectrum of Chinese children with Dent disease, Zhang Aihua, 2020
- BMP1 inhibitor UK-383,367 attenuates renal fibrosis and inflammation in CKD, Zhang Aihua, 2019
- Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus, Zhang Aihua, 2019
- Genetic spectrum of renal disease for 1001 Chinese children based on a multicenter registration system, Zhang Aihua, 2019
- Celastrol attenuates ox-L
Awards
- 2021: First Prize of Jiangsu Provincial Health and Family Planning Commission Medical New Technology Introduction Award
- 2018: First Prize of Jiangsu Provincial Medical New Technology Introduction Award
- 2017: Second Prize of National Women's and Children's Health Science and Technology Award
- 2016: Second Prize of Jiangsu Medical Science and Technology Award
- 2014: Second Prize of Jiangsu Provincial Science and Technology Award
- 2014: First Prize of Ministry of Education Natural Science Award
- 2013: Song Qingling Pediatric Medicine Award
- 2010: Third Prize of Jiangsu Provincial Science and Technology Progress Award
- 2010: Second Prize of Jiangsu Medical Science and Technology Award
- 2009: Third Prize of Jiangsu Provincial Science and Technology Progress Award
