Professor | Zhang Aihua | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Zhang Aihua
Contact Information	zhaihua@njmu.edu.cn
Language ability	Chinese, English
Province	Jiangsu

Upload Avatar (500 x 500)

Name

Zhang Aihua

Contact Information

zhaihua@njmu.edu.cn

Language ability

Chinese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Medical School
Academic Background & Achievements	National Distinguished Young Scientist Fund recipient Expert enjoying special government allowances from the State Council Leading talent in science and technology innovation by the Ministry of Science and Technology Jiangsu Province Distinguished Professor First-level training object of Jiangsu Province '333 Project' Deputy Director of the Children's Hospital Affiliated to Nanjing Medical University/Head of Nephrology Director of the Key Laboratory of Major Pediatric Diseases Research in Jiangsu Province Director of the Pediatric Research Institute of Nanjing Medical University
Awards	2021: First Prize of Jiangsu Provincial Health and Family Planning Commission Medical New Technology Introduction Award 2018: First Prize of Jiangsu Provincial Medical New Technology Introduction Award 2017: Second Prize of National Women's and Children's Health Science and Technology Award 2016: Second Prize of Jiangsu Medical Science and Technology Award 2014: Second Prize of Jiangsu Provincial Science and Technology Award 2014: First Prize of Ministry of Education Natural Science Award 2013: Song Qingling Pediatric Medicine Award 2010: Third Prize of Jiangsu Provincial Science and Technology Progress Award 2010: Second Prize of Jiangsu Medical Science and Technology Award 2009: Third Prize of Jiangsu Provincial Science and Technology Progress Award

University/Lab Affiliation and Title

Nanjing University

Faculty

Medical School

Academic Background & Achievements

National Distinguished Young Scientist Fund recipient
Expert enjoying special government allowances from the State Council
Leading talent in science and technology innovation by the Ministry of Science and Technology
Jiangsu Province Distinguished Professor
First-level training object of Jiangsu Province '333 Project'
Deputy Director of the Children's Hospital Affiliated to Nanjing Medical University/Head of Nephrology
Director of the Key Laboratory of Major Pediatric Diseases Research in Jiangsu Province
Director of the Pediatric Research Institute of Nanjing Medical University

Awards

2021: First Prize of Jiangsu Provincial Health and Family Planning Commission Medical New Technology Introduction Award
2018: First Prize of Jiangsu Provincial Medical New Technology Introduction Award
2017: Second Prize of National Women's and Children's Health Science and Technology Award
2016: Second Prize of Jiangsu Medical Science and Technology Award
2014: Second Prize of Jiangsu Provincial Science and Technology Award
2014: First Prize of Ministry of Education Natural Science Award
2013: Song Qingling Pediatric Medicine Award
2010: Third Prize of Jiangsu Provincial Science and Technology Progress Award
2010: Second Prize of Jiangsu Medical Science and Technology Award
2009: Third Prize of Jiangsu Provincial Science and Technology Progress Award

Areas of Focus	Pediatric Nephrology
Publications	Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI, Zhang Aihua, 2020 Response to comment on 'Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI', Zhang Aihua, 2021 Dimethyl fumarate prevents ferroptosis to attenuate acute kidney injury by acting on NRF2, Zhang Aihua, 2021 Reduced Lon protease 1 expression in podocytes contributes to the pathogenesis of podocytopathy, Zhang Aihua, 2021 MicroRNA-214 promotes chronic kidney disease by disrupting mitochondrial oxidative phosphorylation, Zhang Aihua, 2019 Functional Characterization of PHEX Gene Variants in Children With X-Linked Hypophosphatemic Rickets Shows No Evidence of Genotype-Phenotype Correlation, Zhang Aihua, 2020 Immune Regulator Retinoic Acid-Inducible Gene I (RIG-I) in the Pathogenesis of Cardiovascular Disease, Zhang Aihua, 2022 Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation, Zhang Aihua, 2022 Clinical Potential of Hypoxia Inducible Factors Prolyl Hydroxylase Inhibitors in Treating Nonanemic Diseases, Zhang Aihua, 2022 Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury, Zhang Aihua, 2022 mPGES-2 blockade antagonizes β-cell senescence to ameliorate diabetes by acting on NR4A1, Zhang Aihua, 2022 Computational Systems Pharmacology, Molecular Docking and Experiments Reveal the Protective Mechanism of Li-Da-Qian Mixture in the Treatment of Glomerulonephritis, Zhang Aihua, 2021 Gasdermin E Deletion Attenuates Ureteral Obstruction- and 5/6 Nephrectomy-Induced Renal Fibrosis and Kidney Dysfunction, Zhang Aihua, 2021 Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS, Zhang Aihua, 2021 SIRT1 Alleviates Aldosterone-Induced Podocyte Injury by Suppressing Mitochondrial Dysfunction and NLRP3 Inflammasome Activation, Zhang Aihua, 2021 Blocking AURKA with MK-5108 attenuates renal fibrosis in chronic kidney disease, Zhang Aihua, 2021 Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability, Zhang Aihua, 2021 Clinical and Functional Characterization of Novel INSR Variants in Two Families With Severe Insulin Resistance Syndrome, Zhang Aihua, 2021 Estrogen-Related Receptor γ Agonist DY131 Ameliorates Lipopolysaccharide-Induced Acute Liver Injury, Zhang Aihua, 2021 The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction, Zhang Aihua, 2021 Multi-centre study of the clinical features and gene variant spectrum of Gitelman syndrome in Chinese children, Zhang Aihua, 2021 Gasdermin E deficiency attenuates acute kidney injury by inhibiting pyroptosis and inflammation, Zhang Aihua, 2021 Cilomilast Ameliorates Renal Tubulointerstitial Fibrosis by Inhibiting the TGF-β1-Smad2/3 Signaling Pathway, Zhang Aihua, 2021 Celastrol inhibits intestinal lipid absorption by reprofiling the gut microbiota to attenuate high-fat diet-induced obesity, Zhang Aihua, 2021 Targeting microsomal prostaglandin E synthase 1 to develop drugs treating the inflammatory diseases, Zhang Aihua, 2021 The emerging role of MEIS1 in cell proliferation and differentiation, Zhang Aihua, 2020 Mitochondrial Dysfunction and the AKI to CKD Transition, Zhang Aihua, 2020 miR-214 Protects Against Uric Acid-Induced Endothelial Cell Apoptosis, Zhang Aihua, 2020 LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments, Zhang Aihua, 2020 New Criterion to Evaluate Acute-on-Chronic Kidney Injury Based on the Creatinine Reference Change, Zhang Aihua, 2020 Inhibition of ROCK2 alleviates renal fibrosis and the metabolic disorders in the proximal tubular epithelial cells, Zhang Aihua, 2020 Chinese Society of Pediatric Nephrology and Chinese Medical Doctor Association of Pediatric Nephrology. Consensus recommendations for the care of children receiving chronic dialysis in association with the COVID-19 epidemic, Zhang Aihua, 2020 IPDN-China investigators. IPDN-China promotes the development of pediatric dialysis in China, Zhang Aihua, 2020 Splicing Characterization of CLCNKB Variants in Four Patients With Type III Bartter Syndrome, Zhang Aihua, 2020 Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation, Zhang Aihua, 2020 Ursodeoxycholic acid protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction through acting on ALDH1L2, Zhang Aihua, 2020 Inhibition of PDE4/PDE4B improves renal function and ameliorates inflammation in cisplatin-induced acute kidney injury, Zhang Aihua, 2020 MicroRNA-214 targets COX-2 to antagonize indoxyl sulfate (IS)-induced endothelial cell apoptosis, Zhang Aihua, 2020 Activation of GSDMD contributes to acute kidney injury induced by cisplatin, Zhang Aihua, 2020 Multicenter study of the clinical features and mutation gene spectrum of Chinese children with Dent disease, Zhang Aihua, 2020 BMP1 inhibitor UK-383,367 attenuates renal fibrosis and inflammation in CKD, Zhang Aihua, 2019 Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus, Zhang Aihua, 2019 Genetic spectrum of renal disease for 1001 Chinese children based on a multicenter registration system, Zhang Aihua, 2019 Celastrol attenuates ox-L

Areas of Focus

Pediatric Nephrology

Publications

Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI, Zhang Aihua, 2020
Response to comment on 'Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI', Zhang Aihua, 2021
Dimethyl fumarate prevents ferroptosis to attenuate acute kidney injury by acting on NRF2, Zhang Aihua, 2021
Reduced Lon protease 1 expression in podocytes contributes to the pathogenesis of podocytopathy, Zhang Aihua, 2021
MicroRNA-214 promotes chronic kidney disease by disrupting mitochondrial oxidative phosphorylation, Zhang Aihua, 2019
Functional Characterization of PHEX Gene Variants in Children With X-Linked Hypophosphatemic Rickets Shows No Evidence of Genotype-Phenotype Correlation, Zhang Aihua, 2020
Immune Regulator Retinoic Acid-Inducible Gene I (RIG-I) in the Pathogenesis of Cardiovascular Disease, Zhang Aihua, 2022
Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation, Zhang Aihua, 2022
Clinical Potential of Hypoxia Inducible Factors Prolyl Hydroxylase Inhibitors in Treating Nonanemic Diseases, Zhang Aihua, 2022
Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury, Zhang Aihua, 2022
mPGES-2 blockade antagonizes β-cell senescence to ameliorate diabetes by acting on NR4A1, Zhang Aihua, 2022
Computational Systems Pharmacology, Molecular Docking and Experiments Reveal the Protective Mechanism of Li-Da-Qian Mixture in the Treatment of Glomerulonephritis, Zhang Aihua, 2021
Gasdermin E Deletion Attenuates Ureteral Obstruction- and 5/6 Nephrectomy-Induced Renal Fibrosis and Kidney Dysfunction, Zhang Aihua, 2021
Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS, Zhang Aihua, 2021
SIRT1 Alleviates Aldosterone-Induced Podocyte Injury by Suppressing Mitochondrial Dysfunction and NLRP3 Inflammasome Activation, Zhang Aihua, 2021
Blocking AURKA with MK-5108 attenuates renal fibrosis in chronic kidney disease, Zhang Aihua, 2021
Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability, Zhang Aihua, 2021
Clinical and Functional Characterization of Novel INSR Variants in Two Families With Severe Insulin Resistance Syndrome, Zhang Aihua, 2021
Estrogen-Related Receptor γ Agonist DY131 Ameliorates Lipopolysaccharide-Induced Acute Liver Injury, Zhang Aihua, 2021
The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction, Zhang Aihua, 2021
Multi-centre study of the clinical features and gene variant spectrum of Gitelman syndrome in Chinese children, Zhang Aihua, 2021
Gasdermin E deficiency attenuates acute kidney injury by inhibiting pyroptosis and inflammation, Zhang Aihua, 2021
Cilomilast Ameliorates Renal Tubulointerstitial Fibrosis by Inhibiting the TGF-β1-Smad2/3 Signaling Pathway, Zhang Aihua, 2021
Celastrol inhibits intestinal lipid absorption by reprofiling the gut microbiota to attenuate high-fat diet-induced obesity, Zhang Aihua, 2021
Targeting microsomal prostaglandin E synthase 1 to develop drugs treating the inflammatory diseases, Zhang Aihua, 2021
The emerging role of MEIS1 in cell proliferation and differentiation, Zhang Aihua, 2020
Mitochondrial Dysfunction and the AKI to CKD Transition, Zhang Aihua, 2020
miR-214 Protects Against Uric Acid-Induced Endothelial Cell Apoptosis, Zhang Aihua, 2020
LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments, Zhang Aihua, 2020
New Criterion to Evaluate Acute-on-Chronic Kidney Injury Based on the Creatinine Reference Change, Zhang Aihua, 2020
Inhibition of ROCK2 alleviates renal fibrosis and the metabolic disorders in the proximal tubular epithelial cells, Zhang Aihua, 2020
Chinese Society of Pediatric Nephrology and Chinese Medical Doctor Association of Pediatric Nephrology. Consensus recommendations for the care of children receiving chronic dialysis in association with the COVID-19 epidemic, Zhang Aihua, 2020
IPDN-China investigators. IPDN-China promotes the development of pediatric dialysis in China, Zhang Aihua, 2020
Splicing Characterization of CLCNKB Variants in Four Patients With Type III Bartter Syndrome, Zhang Aihua, 2020
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation, Zhang Aihua, 2020
Ursodeoxycholic acid protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction through acting on ALDH1L2, Zhang Aihua, 2020
Inhibition of PDE4/PDE4B improves renal function and ameliorates inflammation in cisplatin-induced acute kidney injury, Zhang Aihua, 2020
MicroRNA-214 targets COX-2 to antagonize indoxyl sulfate (IS)-induced endothelial cell apoptosis, Zhang Aihua, 2020
Activation of GSDMD contributes to acute kidney injury induced by cisplatin, Zhang Aihua, 2020
Multicenter study of the clinical features and mutation gene spectrum of Chinese children with Dent disease, Zhang Aihua, 2020
BMP1 inhibitor UK-383,367 attenuates renal fibrosis and inflammation in CKD, Zhang Aihua, 2019
Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus, Zhang Aihua, 2019
Genetic spectrum of renal disease for 1001 Chinese children based on a multicenter registration system, Zhang Aihua, 2019
Celastrol attenuates ox-L

Chronic Kidney Disease Acute Kidney Injury Mitochondrial Metabolism Renal Function Pediatric Nephrology Early Intervention Kidney Disease Mechanisms Nephrology Research Kidney Injury Renal Pathology

Zhang Aihua - Nanjing University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us