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Jinzhong Chen
Life Science
Fudan University
Shanghai
Language: Chinese, English
Transgenic
Genetic Engineering
Gene Therapy
Genetic Diseases
Integration Systems
Aav
Recombination
Dna
Mammalian Cells
Gene Expression
Areas of Focus
- Transgenic Systems
- Gene Therapy for Genetic Diseases
- Site-Specific Integration Systems
Work Experience
- 2004-present - Fudan University - Gene Therapy Research Group
- 2006-present - Fudan University - Associate Professor
- 2007-present - Fudan University - Responsible for daily research work of the research group
Academic Background & Achievements
- 1980-1985 Bachelor in Clinical Medicine: Xiangya Medical College, Central South University
- 1998-2001 Master in Genetics: Tongji Medical College, Huazhong University of Science and Technology
- 2001-2004 PhD in Genetics: Institute of Genetics, Fudan University
Publications
- Establishment of an AAV Reverse Infection-Based Array, Xiaoyan Dong, Wenhong Tian, Gang Wang, Zheyue Dong, Wei Shen, Gang Zheng, Xiaobing Wu, Jinglun Xue, Yue Wang, Jinzhong Chen, 2010
- Functional differentiation between Rep-mediated site-specific integration and transcriptional repression of the adeno-associated viral p5 promoter, Yue YB, Xue YY, Tian L, Xue JL, Chen JZ, Jia W, 2010
- A 16-bp RBE element mediated Rep-dependent site-specific integration in AAVS1 transgenic mice for expression of hFIX, Xu ZX, Chen JZ, Yue YB, Zhang JQ, Li ZH, Feng DM, Ruan ZC, Tian L, Xue JL, Wang QJ, Jia W, 2009
- TAT-phiC31 integrase mediates DNA recombination in mammalian cells, Zhang MX, Li ZH, Fang YX, Zhu HZ, Xue JL, Chen JZ, Jia W, 2009
- DAXX interacts with phage Phi C31 integrase and inhibits recombination, Chen JZ, Ji CN, Xu GL, 2006
