2017 - PhD in Computational Biology: University of Chinese Academy of Sciences
2019 - Selected for Shanghai Youth Science and Technology Talent 'Sailing Plan'
2020 - Awarded the Sanofi-Aventis-Young Scientist Award by the Shanghai Institute of Biological Sciences, Chinese Academy of Sciences
2021 - Member of the Youth Innovation Promotion Association of the Chinese Academy of Sciences
2017-2021 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Assistant Researcher, Associate Researcher
2021-Present - School of Life Sciences, Fudan University - Junior Researcher
2019: Selected for Shanghai Youth Science and Technology Talent 'Sailing Plan'
2020: Awarded the Sanofi-Aventis-Young Scientist Award by the Shanghai Institute of Biological Sciences, Chinese Academy of Sciences
Research
Population Genetics Genomics Computational Biology
Asian-European differentiation of schizophrenia-associated genes driven by admixture and natural selection, Sihan Chen, Die Tang, Lian Deng, Shuhua Xu, 2023
A pangenome reference of 36 Chinese populations, Yang Gao, Xiaofei Yang, Hao Chen, Xinjiang Tan, Zhaoqing Yang, Lian Deng, Baonan Wang, Shuang Kong, Songyang Li, Yuhang Cui, Chang Lei, Yimin Wang, Yuwen Pan, Sen Ma, Hao Sun, Xiaohan Xhao, Yingbing Shi, Ziyi Yang, Dongdong Wu, Shaoyuan Wu, Xingming Zhao, Binyin Shi, Li Jin, Zhibin Hu, Chinese Pangenome Consortium (CPC), Yan Lu, Jiayou Chu, Kai Ye, Shuhua Xu, 2023
A protocol for applying a population-specific reference genome assembly to population genetics and medical studies, Lian Deng, Bo Xie, Yimin Wang, Xiaoxi Zhang, Shuhua Xu, 2022
Genetic connections and convergent evolution of tropical indigenous peoples in Asia, Lian Deng, Yuwen Pan, Yinan Wang, Hao Chen, Kai Yuan, Sihan Chen, Dongsheng Lu, Siti Shuhada Mokhtar, Thuhairah Abdul Rahman, Boon-Peng Hoh, Shuhua Xu, 2022
Refining models of archaic–modern human admixture in Eurasia with ArchaicSeeker 2.0, Kai Yuan, Xumin Ni, Chang Liu, Yuwen Pan, Lian Deng, Rui Zhang, Yang Gao, Xuiling Ge, Jiaojiao Liu, Xixian Ma, Haiyi Lou, Taoyang Wu, Shuhua Xu, 2021
Chapter 3: Population Genomics of High-Altitude Adaptation, Lian Deng, Shuhua Xu, 2021
Shared signature of recent positive selection on the TSBP1–BTNL2–HLA-DRA genes in five native populations from North Borneo, Boon-Peng Hoh, Xiaoxi Zhang, Lian Deng, Kai Yuan, Chee-Wei Yew, Woei-Yuh Saw, Mohammad Zahirul Hoque, Farhang Aghakhanian, Maude E Phipps, Yik-Ying Teo, Vijay Kumar Subbiah, Shuhua Xu, 2020
Analysis of five deep-sequenced trio-genomes of the Peninsular Malaysia Orang Asli and North Borneo populations, Lian Deng, Haiyi Lou, Xiaoxi Zhang, Thiruvahindrapuram Bhooma, Dongsheng Lu, Christian R Marshall, Chang Liu, Bo Xie, Wanxing Xu, Lai-Ping Wong, Chee-Wei Yew, Aghakhanian Farhang, Rick Twee-Hee Ong, Mohammad Zahirul Hoque, Abdul Rahman Thuhairah, Bhak Jong, Maude E Phipps, Stephen W Scherer, Yik-Ying Teo, Subbiah Vijay Kumar, Boon-Peng Hoh, Shuhua Xu, 2019
De novo assembly of a Tibetan genome and identification of novel structural variants associated with high altitude adaptation, Ouzhuluobu, Yaoxi He, Haiyi Lou, Chaoying Cui, Lian Deng, Yang Gao, Wangshan, Zheng, Yongbo Guo, Xiaoji Wang, Zhilin Ning, Jun Li, Bin Li, Caijuan Bai, Baimakangzhuo, Gonggalanzi, Dejiquzong, Bianba, Duojizhuoma, Shiming Liu, Tianyi Wu, Shuhua Xu, Xuebin Qi, Bing Su, 2019
Prioritizing natural selection signals from the deep-sequencing genomic data suggests multi-variant adaptation in Tibetan highlanders, Lian Deng, Chao Zhang, Kai Yuan, Yang Gao, Yuwen Pan, Xueling Ge, Yaoxi He, Yuan Yuan, Yan Lu, Xiaoxi Zhang, Hao Chen, Haiyi Lou, Xiaoji Wang, Dongsheng Lu, Jiaojiao Liu, Lei Tian, Qidi Feng, Asifullah Khan, Yajun Yang, Zi-Bing Jin, Jian Yang, Fan Lu, Jia Qu, Longli Kang, Bing Su, Shuhua Xu, 2019
Genomic structure of the native inhabitants of Peninsular Malaysia and North Borneo suggests complex human population history in Southeast Asia, Chee-Wei Yew, Dongsheng Lu, Lian Deng, Lai-Ping Wong, Rick Twee-Hee Ong, Yan Lu, Xiaoji Wang, Yushimah Yunus, Farhang Aghakhanian, Siti Shuhada Mokhtar, Mohammad Zahirul Hoque, Christopher Lok-Yung Voo, Thuhairah Abdul Rahman, Jong Bhak, Maude E. Phipps, Shuhua Xu, Yik-Ying Teo, Subbiah Vijay Kumar, Boon-Peng Hoh, 2018
Adaptation of human skin color in various populations, Lian Deng, Shuhua Xu, 2018
Ancestry variation and footprints of natural selection along the genome in Latin American populations, Lian Deng, Andres Ruiz-Linares, Shuhua Xu, Sijia Wang, 2016
Dissecting the genetic structure and admixture of four geographical Malay populations, Lian Deng, Boon-Peng Hoh, Dongsheng Lu, Woei-Yuh Saw, Rick Twee-Hee Ong, Anuradhani Kasturiratne, H. Janaka de Silva, Bin Alwi Zilfalil, Norihiro Kato, Ananda R. Wickremasinghe, Yik-Ying Teo, Shuhua Xu, 2015
The population genomic landscape of human genetic structure, admixture history and local adaptation in Peninsular Malaysia, Lian Deng, Boon Peng Hoh, Dongsheng Lu, Ruiqing Fu, Maude E. Phipps, Shilin Li, Ab Rajab Nur‑Shafawati, Wan Isa Hatin, Endom Ismail, Siti Shuhada Mokhtar, Li Jin, Bin Alwi Zilfalil, Christian R. Marshall, Stephen W. Scherer, Fahd Al‑Mulla, Shuhua Xu, 2014
Genome-Wide Landscapes of Human Local Adaptation in Asia, Wei Qian, Lian Deng, Dongsheng Lu, Shuhua Xu, 2013
Area of Focus
Human Migration | Divergence Time | Adaptive Evolution | Phenotypic Generation | Evolutionary Process | Genome Structural Variation | Genomics | Evolutionary Biology | Population Genetics | Local Adaptation
