Professor | Motoyuki Hattori | Asia Growth Partners

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Name	Motoyuki Hattori
Contact Information	hattorim@fudan.edu.cn
Language ability	Japanese, English, Chinese
Province	Shanghai

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Name

Motoyuki Hattori

Contact Information

hattorim@fudan.edu.cn

Language ability

Japanese, English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	2005 - Bachelor's Degree in Biochemistry: University of Tokyo 2009 - Ph.D. in Life Science: Tokyo Institute of Technology Postdoctoral Research: Oregon Health & Science University (2009-2012) Assistant Researcher and JST Researcher: University of Tokyo (2012-2015)
Work Experience	2009-2012 - Oregon Health & Science University - Postdoctoral Researcher 2012-2015 - University of Tokyo - Assistant Researcher and JST Researcher

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

2005 - Bachelor's Degree in Biochemistry: University of Tokyo
2009 - Ph.D. in Life Science: Tokyo Institute of Technology
Postdoctoral Research: Oregon Health & Science University (2009-2012)
Assistant Researcher and JST Researcher: University of Tokyo (2012-2015)

Work Experience

2009-2012 - Oregon Health & Science University - Postdoctoral Researcher
2012-2015 - University of Tokyo - Assistant Researcher and JST Researcher

Areas of Focus	Structure and function of ion channels and transporters Development of membrane protein expression and identification techniques
Publications	Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists, Sheng D, Yue C, Jin F, Wang Y, Ichikawa M, Yu Y, Guo CR, Hattori M, 2023 Structural insights into the allosteric inhibition of P2X4 receptors, Shen C, Zhang Y, Cui W, Zhao Y, Sheng D, Teng X, Shao M, Ichikawa M, Wang J, Hattori M, 2023 Antithetic effects of agonists and antagonists on the structural fluctuations of TRPV1 channel, Sumino A, Zhao Y, Mukai D, Sumikama T, Puppulin L, Hattori M, Shibata M, 2023 The structure of MgtE in the absence of magnesium provides new insights into channel gating, Jin F, Sun M, Fujii T, Yamada Y, Wang J, Maturana AD, Wada M, Su S, Ma J, Takeda H, Kusakizako T, Tomita A, Nakada-Nakura Y, Liu K, Uemura T, Nomura Y, Nomura N, Ito K, Nureki O, Namba K, Iwata S, Yu Y, Hattori M, 2021 Structural basis for the Mg2+ recognition and regulation of the CorC Mg2+ transporter, Huang Y, Jin F, Funato Y, Xu Z, Zhu W, Wang J, Sun M, Zhao Y, Yu Y, Miki H, Hattori M, 2021 TMC1 and TMC2 Proteins Are Pore-Forming Subunits of Mechanosensitive Ion Channels, Jia Y, Zhao Y, Kusakizako T, Wang Y, Pan C, Zhang Y, Nureki O, Hattori M, Yan Z, 2020 Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP, Li M, Wang Y, Banerjee R, Marinelli F, Silberberg S, Faraldo-Gomez J, Hattori M, Swartz K, 2019 Druggable negative allosteric site of P2X3 receptors, Wang J, Wang Y, Cui WW, Huang Y, Yang Y, Liu Y, Zhao WS, Cheng XY, Sun WS, Cao P, Zhu MX, Wang R, Hattori M, Yu Y, 2018

Areas of Focus

Structure and function of ion channels and transporters
Development of membrane protein expression and identification techniques

Publications

Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists, Sheng D, Yue C, Jin F, Wang Y, Ichikawa M, Yu Y, Guo CR, Hattori M, 2023
Structural insights into the allosteric inhibition of P2X4 receptors, Shen C, Zhang Y, Cui W, Zhao Y, Sheng D, Teng X, Shao M, Ichikawa M, Wang J, Hattori M, 2023
Antithetic effects of agonists and antagonists on the structural fluctuations of TRPV1 channel, Sumino A, Zhao Y, Mukai D, Sumikama T, Puppulin L, Hattori M, Shibata M, 2023
The structure of MgtE in the absence of magnesium provides new insights into channel gating, Jin F, Sun M, Fujii T, Yamada Y, Wang J, Maturana AD, Wada M, Su S, Ma J, Takeda H, Kusakizako T, Tomita A, Nakada-Nakura Y, Liu K, Uemura T, Nomura Y, Nomura N, Ito K, Nureki O, Namba K, Iwata S, Yu Y, Hattori M, 2021
Structural basis for the Mg2+ recognition and regulation of the CorC Mg2+ transporter, Huang Y, Jin F, Funato Y, Xu Z, Zhu W, Wang J, Sun M, Zhao Y, Yu Y, Miki H, Hattori M, 2021
TMC1 and TMC2 Proteins Are Pore-Forming Subunits of Mechanosensitive Ion Channels, Jia Y, Zhao Y, Kusakizako T, Wang Y, Pan C, Zhang Y, Nureki O, Hattori M, Yan Z, 2020
Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP, Li M, Wang Y, Banerjee R, Marinelli F, Silberberg S, Faraldo-Gomez J, Hattori M, Swartz K, 2019
Druggable negative allosteric site of P2X3 receptors, Wang J, Wang Y, Cui WW, Huang Y, Yang Y, Liu Y, Zhao WS, Cheng XY, Sun WS, Cao P, Zhu MX, Wang R, Hattori M, Yu Y, 2018

Ion Channels Transporters Membrane Proteins Structure Function Expression Identification Techniques Development Biophysics

Senfang Sui - Tsinghua University

Jin Changwen - Peking University

Tao Jiang - University of Chinese Academy of Sciences

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