Upload Avatar (500 x 500)
Motoyuki Hattori
Life Science
Fudan University
Shanghai
Language: Japanese, English, Chinese
Ion Channels
Transporters
Membrane Proteins
Structure
Function
Expression
Identification
Techniques
Development
Biophysics
Areas of Focus
- Structure and function of ion channels and transporters
- Development of membrane protein expression and identification techniques
Work Experience
- 2009-2012 - Oregon Health & Science University - Postdoctoral Researcher
- 2012-2015 - University of Tokyo - Assistant Researcher and JST Researcher
Academic Background & Achievements
- 2005 - Bachelor's Degree in Biochemistry: University of Tokyo
- 2009 - Ph.D. in Life Science: Tokyo Institute of Technology
- Postdoctoral Research: Oregon Health & Science University (2009-2012)
- Assistant Researcher and JST Researcher: University of Tokyo (2012-2015)
Publications
- Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists, Sheng D, Yue C, Jin F, Wang Y, Ichikawa M, Yu Y, Guo CR, Hattori M, 2023
- Structural insights into the allosteric inhibition of P2X4 receptors, Shen C, Zhang Y, Cui W, Zhao Y, Sheng D, Teng X, Shao M, Ichikawa M, Wang J, Hattori M, 2023
- Antithetic effects of agonists and antagonists on the structural fluctuations of TRPV1 channel, Sumino A, Zhao Y, Mukai D, Sumikama T, Puppulin L, Hattori M, Shibata M, 2023
- The structure of MgtE in the absence of magnesium provides new insights into channel gating, Jin F, Sun M, Fujii T, Yamada Y, Wang J, Maturana AD, Wada M, Su S, Ma J, Takeda H, Kusakizako T, Tomita A, Nakada-Nakura Y, Liu K, Uemura T, Nomura Y, Nomura N, Ito K, Nureki O, Namba K, Iwata S, Yu Y, Hattori M, 2021
- Structural basis for the Mg2+ recognition and regulation of the CorC Mg2+ transporter, Huang Y, Jin F, Funato Y, Xu Z, Zhu W, Wang J, Sun M, Zhao Y, Yu Y, Miki H, Hattori M, 2021
- TMC1 and TMC2 Proteins Are Pore-Forming Subunits of Mechanosensitive Ion Channels, Jia Y, Zhao Y, Kusakizako T, Wang Y, Pan C, Zhang Y, Nureki O, Hattori M, Yan Z, 2020
- Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP, Li M, Wang Y, Banerjee R, Marinelli F, Silberberg S, Faraldo-Gomez J, Hattori M, Swartz K, 2019
- Druggable negative allosteric site of P2X3 receptors, Wang J, Wang Y, Cui WW, Huang Y, Yang Y, Liu Y, Zhao WS, Cheng XY, Sun WS, Cao P, Zhu MX, Wang R, Hattori M, Yu Y, 2018
