Professor | Lei Sun | Asia Growth Partners

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Name	Lei Sun
Contact Information	lei_sun@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Lei Sun

Contact Information

lei_sun@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	1998-2002: Bachelor's Degree in Life Sciences, Fudan University 2002-2008: Ph.D. in Developmental Biology, Fudan University Postdoctoral Research at The Scripps Research Institute, USA Co-founder and CTO of Shanghai Nearshore Biotechnology Co., Ltd. Supported by the National Major New Drug Creation Special Fund Supported by Shanghai Pujiang Talent Program
Work Experience	2008-2011: Postdoctoral Researcher at The Scripps Research Institute, USA 2011-2017: Lecturer at the University of Texas Southwestern Medical Center 2017-2019: Co-founder and CTO of Shanghai Nearshore Biotechnology Co., Ltd. 2019-present: Junior Researcher at the Institute of Developmental Biology, Fudan University 2020-present: Dual-appointed PI at the Oncology Department, Zhongshan Hospital affiliated with Fudan University
Awards	Supported by the National Major New Drug Creation Special Fund Supported by Shanghai Pujiang Talent Program

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

1998-2002: Bachelor's Degree in Life Sciences, Fudan University
2002-2008: Ph.D. in Developmental Biology, Fudan University
Postdoctoral Research at The Scripps Research Institute, USA
Co-founder and CTO of Shanghai Nearshore Biotechnology Co., Ltd.
Supported by the National Major New Drug Creation Special Fund
Supported by Shanghai Pujiang Talent Program

Work Experience

2008-2011: Postdoctoral Researcher at The Scripps Research Institute, USA
2011-2017: Lecturer at the University of Texas Southwestern Medical Center
2017-2019: Co-founder and CTO of Shanghai Nearshore Biotechnology Co., Ltd.
2019-present: Junior Researcher at the Institute of Developmental Biology, Fudan University
2020-present: Dual-appointed PI at the Oncology Department, Zhongshan Hospital affiliated with Fudan University

Awards

Supported by the National Major New Drug Creation Special Fund
Supported by Shanghai Pujiang Talent Program

Areas of Focus	Immune regulation mechanisms caused by genetic and physiological factors Development and clinical application of new immunotherapy drugs
Publications	Blood molecular markers associated with COVID-19 immunopathology and multi-organ damage, Yan-Mei Chen, Yuanting Zheng, Ying Yu, Yunzhi Wang, Qingxia Huang, Feng Qian, Lei Sun, Zhi-Gang Song, Ziyin Chen, Jinwen Feng, Yanpeng An, Jingcheng Yang, Zhenqiang Su, Shanyue Sun, Fahui Dai, Qinsheng Chen, Qinwei Lu, Pengcheng Li, Yun Ling, Zhong Yang, Huiru Tang, Leming Shi, Li Jin, Edward C Holmes, Chen Ding, Tong-Yu Zhu, Yong-Zhen Zhang, 2020 Synergistic effect of ibrutinib and CD19 CAR-T cells on Raji cells in vivo and in vitro, Meijing Liu, Xuelin Wang, Zheng Li, Rui Zhang, Juan Mu, Yanyu Jiang, Qi Deng, Lei Sun, 2020 HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections, Lei Sun, Zhengfan Jiang, Victoria A. Acosta-Rodriguez, Michael Berger, Xin Du, Jin Huk Choi, Jianhui Wang, Kuan-wen Wang, Gokhul K. Kilaru, Jennifer A. Mohawk, Jiexia Quan, Lindsay Scott, Sara Hildebrand, Xiaohong Li, Miao Tang, Xiaoming Zhan, Anne R. Murray, Diantha La Vine, Eva Marie Y. Moresco, Joseph S. Takahashi, Bruce Beutler, 2017 Generation of a Mouse Full-length Balancer with Versatile Cassette-shuttling Selection Strategy, Zhisheng Ye, Lei Sun, Rongbo Li, Min Han, Yuan Zhuang, Xiaohui Wu, Tian Xu, 2016 MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands, Katharina Brandl, Lei Sun, Christina Neppl, Owen M. Siggs, Sylvain M. Le Gall, Wataru Tomisato, Xiaohong Li, Xin Du, Daniela N. Maennel, Carl P. Blobel, Bruce Beutler, 2010 A Mitotic Recombination System for Mouse Chromosome 17, Lei Sun, Xiaohui Wu, Min Han, Tian Xu, Yuan Zhuang, 2008

Areas of Focus

Immune regulation mechanisms caused by genetic and physiological factors
Development and clinical application of new immunotherapy drugs

Publications

Blood molecular markers associated with COVID-19 immunopathology and multi-organ damage, Yan-Mei Chen, Yuanting Zheng, Ying Yu, Yunzhi Wang, Qingxia Huang, Feng Qian, Lei Sun, Zhi-Gang Song, Ziyin Chen, Jinwen Feng, Yanpeng An, Jingcheng Yang, Zhenqiang Su, Shanyue Sun, Fahui Dai, Qinsheng Chen, Qinwei Lu, Pengcheng Li, Yun Ling, Zhong Yang, Huiru Tang, Leming Shi, Li Jin, Edward C Holmes, Chen Ding, Tong-Yu Zhu, Yong-Zhen Zhang, 2020
Synergistic effect of ibrutinib and CD19 CAR-T cells on Raji cells in vivo and in vitro, Meijing Liu, Xuelin Wang, Zheng Li, Rui Zhang, Juan Mu, Yanyu Jiang, Qi Deng, Lei Sun, 2020
HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections, Lei Sun, Zhengfan Jiang, Victoria A. Acosta-Rodriguez, Michael Berger, Xin Du, Jin Huk Choi, Jianhui Wang, Kuan-wen Wang, Gokhul K. Kilaru, Jennifer A. Mohawk, Jiexia Quan, Lindsay Scott, Sara Hildebrand, Xiaohong Li, Miao Tang, Xiaoming Zhan, Anne R. Murray, Diantha La Vine, Eva Marie Y. Moresco, Joseph S. Takahashi, Bruce Beutler, 2017
Generation of a Mouse Full-length Balancer with Versatile Cassette-shuttling Selection Strategy, Zhisheng Ye, Lei Sun, Rongbo Li, Min Han, Yuan Zhuang, Xiaohui Wu, Tian Xu, 2016
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands, Katharina Brandl, Lei Sun, Christina Neppl, Owen M. Siggs, Sylvain M. Le Gall, Wataru Tomisato, Xiaohong Li, Xin Du, Daniela N. Maennel, Carl P. Blobel, Bruce Beutler, 2010
A Mitotic Recombination System for Mouse Chromosome 17, Lei Sun, Xiaohui Wu, Min Han, Tian Xu, Yuan Zhuang, 2008

Genetics Physiology Immune Regulation Immunotherapy Drug Development Clinical Application Covid-19 Molecular Markers Tlr3 Transcription Viral Infections

Yinghui Zhu - Tongji University

Yinghui Zhu - Tongji University

Weineng Fu - China Medical University

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