Professor | Wei Yu | Asia Growth Partners

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Name	Wei Yu
Contact Information	yuw@fudan.edu.cn
Language ability	English, Chinese
Province	Shanghai

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Name

Wei Yu

Contact Information

yuw@fudan.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	2009 - PhD: Fudan University Achievement: Published over ten papers as first or corresponding author in journals like Cell, Molecular Cell, Nature Communications, PNAS, Cell Reports, JBC
Work Experience	2009-2014 - University of Wisconsin-Madison - Postdoctoral and Assistant Researcher 2014-present - Fudan University - Researcher and Doctoral Supervisor
Awards	Shanghai 'Oriental Scholar' Distinguished Professor National High-level Overseas Talent Introduction Program

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

2009 - PhD: Fudan University
Achievement: Published over ten papers as first or corresponding author in journals like Cell, Molecular Cell, Nature Communications, PNAS, Cell Reports, JBC

Work Experience

2009-2014 - University of Wisconsin-Madison - Postdoctoral and Assistant Researcher
2014-present - Fudan University - Researcher and Doctoral Supervisor

Awards

Shanghai 'Oriental Scholar' Distinguished Professor
National High-level Overseas Talent Introduction Program

Areas of Focus	Metabolic Regulation of Aging
Publications	Acetylation Stabilizes Phosphoglycerate Dehydrogenase by Disrupting the Interaction of E3 Ligase RNF5 to Promote Breast Tumorigenesis, Wang C, Wan X, Yu T, Huang Z, Shen C, Qi Q, Xiang S, Chen X, Arbely E, Ling ZQ, Liu CY, Yu W, 2020 Cisplatin inhibits SIRT3-deacetylation MTHFD2 to disturb cellular redox balance in colorectal cancer cell, Wan X, Wang C, Huang Z, Zhou D, Xiang S, Qi Q, Chen X, Arbely E, Liu CY, Du P, Yu W, 2020 LAMB3 promotes tumour progression through the AKT–FOXO3/4 axis and is transcriptionally regulated by the BRD2/acetylated ELK4 complex in colorectal cancer, Zhu Z, Song J, Guo Y, Huang Z, Chen X, Dang X, Huang Y, Wang Y, Ou W, Yang Y, Yu W, Liu CY, Cui L, 2020 CCBE1 promotes tumor lymphangiogenesis and is negatively regulated by TGFβ signaling in colorectal cancer, Song J, Chen W, Cui X, Huang Z, Wen D, Yang Y, Yu W, Cui L, Liu CY, 2020 Deacetylation of Serine Hydroxymethyl-transferase 2 by SIRT3 promotes Colorectal Carcinogenesis, Wei Z, Song J, Wang G, Cui X, Zheng J, Tang Y, Chen X, Li J, Cui L, Liu CY, Yu W, 2018 Acetylation promotes TyrRS nuclear translocation to prevent oxidative damage, Cao X, Li C, Xiao S, Tang Y, Huang J, Zhao S, Li X, Li J, Zhang R, Yu W, 2017 Loss of SIRT3 Provides Growth Advantage for B Cell Malignancies, Yu W, Denu RA, Krautkramer KA, Grindle KM, Yang DT, Asimakopoulos F, Hematti P, Denu JM, 2016 SIRT3 deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status, Yu W, Dittenhafer-Reed KE, Denu JM, 2012 Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction, Hallows WC, Yu W, Smith BC, Devries MK, Ellinger JJ, Someya S, Shortreed MR, Prolla T, Markley JL, Smith LM, Zhao S, Guan KL, Denu JM, 2011 Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction, Someya S, Yu W, Hallows WC, Xu J, Vann JM, Leeuwenburgh C, Tanokura M, Denu JM, Prolla TA, 2010 Regulation of cellular metabolism by protein lysine acetylation, Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Yang P, Li H, Li Y, Shi J, Qin l, Lei Q, Xiong Y, Guan KL, 2010 Lysine 88 Acetylation Negatively Regulates Ornithine Carbamoyltransferase Activity in Response to Nutrient Signals, Yu W, Lin Y, Yao J, Huang W, Lei Q, Xiong Y, Zhao S, Guan KL, 2009

Areas of Focus

Metabolic Regulation of Aging

Publications

Acetylation Stabilizes Phosphoglycerate Dehydrogenase by Disrupting the Interaction of E3 Ligase RNF5 to Promote Breast Tumorigenesis, Wang C, Wan X, Yu T, Huang Z, Shen C, Qi Q, Xiang S, Chen X, Arbely E, Ling ZQ, Liu CY, Yu W, 2020
Cisplatin inhibits SIRT3-deacetylation MTHFD2 to disturb cellular redox balance in colorectal cancer cell, Wan X, Wang C, Huang Z, Zhou D, Xiang S, Qi Q, Chen X, Arbely E, Liu CY, Du P, Yu W, 2020
LAMB3 promotes tumour progression through the AKT–FOXO3/4 axis and is transcriptionally regulated by the BRD2/acetylated ELK4 complex in colorectal cancer, Zhu Z, Song J, Guo Y, Huang Z, Chen X, Dang X, Huang Y, Wang Y, Ou W, Yang Y, Yu W, Liu CY, Cui L, 2020
CCBE1 promotes tumor lymphangiogenesis and is negatively regulated by TGFβ signaling in colorectal cancer, Song J, Chen W, Cui X, Huang Z, Wen D, Yang Y, Yu W, Cui L, Liu CY, 2020
Deacetylation of Serine Hydroxymethyl-transferase 2 by SIRT3 promotes Colorectal Carcinogenesis, Wei Z, Song J, Wang G, Cui X, Zheng J, Tang Y, Chen X, Li J, Cui L, Liu CY, Yu W, 2018
Acetylation promotes TyrRS nuclear translocation to prevent oxidative damage, Cao X, Li C, Xiao S, Tang Y, Huang J, Zhao S, Li X, Li J, Zhang R, Yu W, 2017
Loss of SIRT3 Provides Growth Advantage for B Cell Malignancies, Yu W, Denu RA, Krautkramer KA, Grindle KM, Yang DT, Asimakopoulos F, Hematti P, Denu JM, 2016
SIRT3 deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status, Yu W, Dittenhafer-Reed KE, Denu JM, 2012
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction, Hallows WC, Yu W, Smith BC, Devries MK, Ellinger JJ, Someya S, Shortreed MR, Prolla T, Markley JL, Smith LM, Zhao S, Guan KL, Denu JM, 2011
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction, Someya S, Yu W, Hallows WC, Xu J, Vann JM, Leeuwenburgh C, Tanokura M, Denu JM, Prolla TA, 2010
Regulation of cellular metabolism by protein lysine acetylation, Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Yang P, Li H, Li Y, Shi J, Qin l, Lei Q, Xiong Y, Guan KL, 2010
Lysine 88 Acetylation Negatively Regulates Ornithine Carbamoyltransferase Activity in Response to Nutrient Signals, Yu W, Lin Y, Yao J, Huang W, Lei Q, Xiong Y, Zhao S, Guan KL, 2009

Metabolism Aging Deacetylation Enzymes Cellular Biology Molecular Biology Cancer Redox Balance Sirt3 Tumorigenesis

Changdong Lin - Tongji University

Chenfei Wang - Tongji University

Hongbing Wang - Tongji University

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