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Xueyan Yang
Life Science
Fudan University
Shanghai
Language: English, Chinese
Genetics
Birth Defects
Neural Tube Defects
Congenital Heart Disease
Pathogenesis
Mutation
Genetic Research
Developmental Biology
Human Genetics
Medical Genetics
Areas of Focus
- Genetic basis and pathogenesis of major birth defects
Work Experience
- 2008-Present - Fudan University - Lecturer, Associate Researcher
Academic Background & Achievements
- 1995-1999 Bachelor: Huazhong Agricultural University
- 1999-2005 PhD: Fudan University
- 2005-2008 Postdoctoral Research: University of Bath
- 2013-2014 Visiting Scholar: National Institute of Health (NIH)
Publications
- A mutation in TBXT causes congenital vertebral malformations in humans and mice, Chen S, Lei Y, Yang Y, Liu C, Kuang L, Jin L, Finnell RH, Yang X*, Wang H*, 2023
- Deleterious Rare Mutations of GLI1 Dysregulate Sonic Hedgehog Signaling in Human Congenital Heart Disease, Peng R, Li B, Chen S, Shi Z, Yu L, Gao Y, Yang X, Lu L, Wang H, 2022
- Rare variants in TULP3 abolish the suppressive effect on sonic hedgehog signaling and contribute to human neural tube defects, Kuang L, Jiang Y, Chen S, Su K, Peng R, Yang X*, Wang H*, 2021
- Genetic variants of TBX6 and TBXT identified in patients with congenital scoliosis in Southern China, Feng X, Cheung JPY, Je JSH, Cheung PWH, Chen S, Yue M, Wang N, Choi VNT, Yang X, Song YQ, Luk KDK, Gao B, 2021
- Rare mutations in the autophagy-regulating gene AMBRA1 contribute to human neural tube defects, Ye J, Tong Y, Lv J, Peng R, Chen S, Kuang L, Su K, Zheng Y, Zhang T, Zhang F, Jin L, Yang X*, Wang H*, 2020
- Association between rare variants in specific functional pathways and human neural tube defects multiple subphenotypes, Zou J, Wang F, Yang X, Wang H, Niswander L, Zhang T, Li H, 2020
- A functional indel polymorphism rs34396413 in TFAP2A intron-5 significantly increases female encephalocele risk in Han Chinese population, Su K, Chen S, Ye J, Kuang L, Zhang T, Wang H, Yang X*, 2019
- Novel mutations of AXIN2 identified in a Chinese Congenital Heart Disease Cohort, Zhu MJ, Ma XY, Ding PC, Tang HF, Peng R, Lu L, Li PQ, Qiao B, Yang XY, Zheng YF, Wang HY, Gao YQ, Chen FS, 2019
Awards
- 2020: Second Prize in Shanghai and Third Prize Nationally in National College Student Biology Competition
- 2019: Third Prize in National University Life Sciences Microlecture Teaching Competition
