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Jinru Zhang
Life Science
Fudan University
Shanghai
Language: Chinese, English
Crystallography
Cryo-Electron Microscopy
Biochemistry
Molecular Biology
Cell Biology
Computational Biology
Membrane Proteins
Antibiotics
Hypertension Drugs
Interaction Mechanisms
Areas of Focus
- Interaction mechanisms between antibiotics and membrane proteins
- Interaction mechanisms between hypertension drugs and membrane protein targets
Work Experience
- 2015-08 to 2017-02 - Assistant Researcher at Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
- 2017-02 to 2022-06 - Postdoctoral Researcher at Stanford University School of Medicine
- 2017-08 to 2017-11 - Visiting Scholar at Harvard University
- 2022-06 to Present - Principal Investigator at School of Life Sciences, Fudan University
Academic Background & Achievements
- 2015 - PhD in Organic Chemistry: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
- Achievement: Published 11 academic journal papers including in Nature, Nature Chemical Biology, and Nature Communication
Publications
- Structure and mechanism of blood-brain-barrier lipid transporter MFSD2A, Chase A P Wood, Jinru Zhang, Deniz Aydin, Yan Xu, Benjamin J Andreone, Urs H Langen, Ron O Dror, Chenghua Gu, Liang Feng, 2021
- Structure and Mechanism of the Mitochondrial Ca 2+ Uniporter Holocomplex, Fan M, Zhang J, Tsai CW, Orlando BJ, Rodriguez M, Xu Y, Liao M, Tsai MF, Feng L, 2020
- Structure and Mechanism of the Cation-Chloride Cotransporter NKCC1, Chew TA, Orlando BJ, Zhang J, Latorraca NR, Wang A, Hollingsworth SA, Chen DH, Dror RO, Liao M, Feng L, 2019
- Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter, Minrui Fan, Jianxiu Zhang, Chien-Ling Lee, Jinru Zhang, Liang Feng, 2023
- GyrI-like proteins catalyze cyclopropanoid hydrolysis to confer cellular protection, Yuan H, Zhang J, Cai Y, Wu S, Yang K, Chan HCS, Huang W, Jin WB, Li Y, Yin Y, Igarashi Y, Yuan S, Zhou J, Tang GL, 2017
- Structural basis of condensation-like domain catalyzed macrocyclization in nonribosomal peptide synthetase, Jinru Zhang, Nicholas Liu, Zhou Gong, Ralph A. Cacho, Wenming Qin, Chun Tang, Yi Tang, Jiahai Zhou, 2016
