Professor | Jinru Zhang | Asia Growth Partners

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Name	Jinru Zhang
Contact Information	zhangjr@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Jinru Zhang

Contact Information

zhangjr@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	2015 - PhD in Organic Chemistry: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences Achievement: Published 11 academic journal papers including in Nature, Nature Chemical Biology, and Nature Communication
Work Experience	2015-08 to 2017-02 - Assistant Researcher at Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 2017-02 to 2022-06 - Postdoctoral Researcher at Stanford University School of Medicine 2017-08 to 2017-11 - Visiting Scholar at Harvard University 2022-06 to Present - Principal Investigator at School of Life Sciences, Fudan University

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

2015 - PhD in Organic Chemistry: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
Achievement: Published 11 academic journal papers including in Nature, Nature Chemical Biology, and Nature Communication

Work Experience

2015-08 to 2017-02 - Assistant Researcher at Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
2017-02 to 2022-06 - Postdoctoral Researcher at Stanford University School of Medicine
2017-08 to 2017-11 - Visiting Scholar at Harvard University
2022-06 to Present - Principal Investigator at School of Life Sciences, Fudan University

Areas of Focus	Interaction mechanisms between antibiotics and membrane proteins Interaction mechanisms between hypertension drugs and membrane protein targets
Publications	Structure and mechanism of blood-brain-barrier lipid transporter MFSD2A, Chase A P Wood, Jinru Zhang, Deniz Aydin, Yan Xu, Benjamin J Andreone, Urs H Langen, Ron O Dror, Chenghua Gu, Liang Feng, 2021 Structure and Mechanism of the Mitochondrial Ca 2+ Uniporter Holocomplex, Fan M, Zhang J, Tsai CW, Orlando BJ, Rodriguez M, Xu Y, Liao M, Tsai MF, Feng L, 2020 Structure and Mechanism of the Cation-Chloride Cotransporter NKCC1, Chew TA, Orlando BJ, Zhang J, Latorraca NR, Wang A, Hollingsworth SA, Chen DH, Dror RO, Liao M, Feng L, 2019 Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter, Minrui Fan, Jianxiu Zhang, Chien-Ling Lee, Jinru Zhang, Liang Feng, 2023 GyrI-like proteins catalyze cyclopropanoid hydrolysis to confer cellular protection, Yuan H, Zhang J, Cai Y, Wu S, Yang K, Chan HCS, Huang W, Jin WB, Li Y, Yin Y, Igarashi Y, Yuan S, Zhou J, Tang GL, 2017 Structural basis of condensation-like domain catalyzed macrocyclization in nonribosomal peptide synthetase, Jinru Zhang, Nicholas Liu, Zhou Gong, Ralph A. Cacho, Wenming Qin, Chun Tang, Yi Tang, Jiahai Zhou, 2016

Areas of Focus

Interaction mechanisms between antibiotics and membrane proteins
Interaction mechanisms between hypertension drugs and membrane protein targets

Publications

Structure and mechanism of blood-brain-barrier lipid transporter MFSD2A, Chase A P Wood, Jinru Zhang, Deniz Aydin, Yan Xu, Benjamin J Andreone, Urs H Langen, Ron O Dror, Chenghua Gu, Liang Feng, 2021
Structure and Mechanism of the Mitochondrial Ca 2+ Uniporter Holocomplex, Fan M, Zhang J, Tsai CW, Orlando BJ, Rodriguez M, Xu Y, Liao M, Tsai MF, Feng L, 2020
Structure and Mechanism of the Cation-Chloride Cotransporter NKCC1, Chew TA, Orlando BJ, Zhang J, Latorraca NR, Wang A, Hollingsworth SA, Chen DH, Dror RO, Liao M, Feng L, 2019
Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter, Minrui Fan, Jianxiu Zhang, Chien-Ling Lee, Jinru Zhang, Liang Feng, 2023
GyrI-like proteins catalyze cyclopropanoid hydrolysis to confer cellular protection, Yuan H, Zhang J, Cai Y, Wu S, Yang K, Chan HCS, Huang W, Jin WB, Li Y, Yin Y, Igarashi Y, Yuan S, Zhou J, Tang GL, 2017
Structural basis of condensation-like domain catalyzed macrocyclization in nonribosomal peptide synthetase, Jinru Zhang, Nicholas Liu, Zhou Gong, Ralph A. Cacho, Wenming Qin, Chun Tang, Yi Tang, Jiahai Zhou, 2016

Crystallography Cryo-Electron Microscopy Biochemistry Molecular Biology Cell Biology Computational Biology Membrane Proteins Antibiotics Hypertension Drugs Interaction Mechanisms

Xiaobin Wu - Shanghai Normal University

Xiaobin Wu - Shanghai Normal University

Yihua Chen - University of Chinese Academy of Sciences

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