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Xuelian Zhang
Life Science
Fudan University
Shanghai
Language: Chinese, English
Tuberculosis
Drug Resistance
Protein Modifications
Host-Pathogen
Immune Interaction
New Drugs
Mechanisms
Pathogenesis
Mycobacterium
Infection
Areas of Focus
- Tuberculosis Research
- Protein Post-Translational Modifications
- Host-Pathogen Interactions
- Antituberculosis Drug Mechanisms
Work Experience
- 2005-present - Fudan University - Lecturer, Associate Professor
Academic Background & Achievements
- 2003 PhD: Nanjing Agricultural University
- 2003-2005 Postdoctoral: Fudan University
- 2009-2010 Visiting Scholar: Johns Hopkins University
Publications
- Structural insights into RNase J that plays an essential role in Mycobacterium tuberculosis RNA metabolism, Luyao Bao, Juan Hu, Bowen Zhan, Mingzhe Chi, Zhengyang Li, Sen Wang, Chan Shan, Zhaozhao Zhao, Yanchao Guo, Xiaoming Ding, Chaoneng Ji, Shengce Tao, Ting Ni, Xuelian Zhang, Guoping Zhao, Jixi Li, 2023
- Acetylation of cyclic adenosine monophosphate receptor protein by acetyl phosphate modulates mycobacteria virulence, Yuchang Di, Siyue Xu, Mingzhe Chi, Youwei Hu, Xiao Zhang, Honghai Wang, Wenhong Zhang, Xuelian Zhang, 2023
- Patpat: a public proteomics dataset search framework, Weiheng Liao, Xuelian Zhang, 2023
- Mycobacterium tuberculosis PE_PGRS19 induces pyroptosis through a non-Classical caspase-11/GSDMD pathway in macrophages, Jianing Qian, Youwei Hu, Xiao Zhang, Mingzhe Chi, Siyue Xu, Honghai Wang, Xuelian Zhang, 2022
- Mycobacterium tuberculosis ESX-1-secreted substrate protein EspC promotes mycobacterial survival through endoplasmic reticulum stress-mediated apoptosis, Qinglong Guo, Jing Bi, Honghai Wang, Xuelian Zhang, 2021
- Acetylation of lysine 182 inhibits the ability of Mycobacterium tuberculosis DosR to bind DNA and regulate gene expression during hypoxia, Jing Bi, Zongchao Gou, Fengzhu Zhou, Yiqing Chen, Jianhua Gan, Jun Liu, Honghai Wang, Xuelian Zhang, 2018
- Role of the PE/PPE Family in Host–Pathogen Interactions and Prospects for Anti-Tuberculosis Vaccine and Diagnostic Tool Design, Jianing Qian, Run Chen, Honghai Wang, Xuelian Zhang, 2020
- ESX Secretion-Associated Protein C from Mycobacterium tuberculosis Induces Macrophage Activation Through the Toll-Like Receptor-4/Mitogen-Activated Protein Kinase Signaling Pathway, Qinglong Guo, Jing Bi, Ming Li, Wenxue Ge, Ying Xu, Weixing Fan, Honghai Wang, Xuelian Zhang, 2019
Awards
- 2015: Shanghai Natural Science Third Prize for 'Research on Tuberculosis Drug Resistance and Control Strategies'
- 2018: First Prize (Innovation) in the Third National College Student Life Science Innovation and Entrepreneurship Competition
