Professor | Yu-Fang Zheng | Asia Growth Partners

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Name	Yu-Fang Zheng
Contact Information	zhengyf@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Yu-Fang Zheng

Contact Information

zhengyf@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	1997 - Bachelor's Degree in Biological Sciences and Technology: Tsinghua University 1999 - Master's Degree in Biophysics: Tsinghua University 2004 - Ph.D. in Physiology, Biophysics, and Molecular Medicine: Cornell University 2004-2007 - Postdoctoral Research: Yale University 2016 - Deputy Researcher PI: Fudan University Affiliated Obstetrics and Gynecology Hospital 2017 - Researcher: Fudan University Award: Shanghai Pujiang Talent Program Award: Fudan University Zhuoxue Talent Program
Work Experience	2004-2007 - Postdoctoral Research: Yale University 2007-Present - Researcher: Fudan University 2016-Present - Deputy Researcher PI: Fudan University Affiliated Obstetrics and Gynecology Hospital
Awards	Shanghai Pujiang Talent Program Fudan University Zhuoxue Talent Program

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

1997 - Bachelor's Degree in Biological Sciences and Technology: Tsinghua University
1999 - Master's Degree in Biophysics: Tsinghua University
2004 - Ph.D. in Physiology, Biophysics, and Molecular Medicine: Cornell University
2004-2007 - Postdoctoral Research: Yale University
2016 - Deputy Researcher PI: Fudan University Affiliated Obstetrics and Gynecology Hospital
2017 - Researcher: Fudan University
Award: Shanghai Pujiang Talent Program
Award: Fudan University Zhuoxue Talent Program

Work Experience

2004-2007 - Postdoctoral Research: Yale University
2007-Present - Researcher: Fudan University
2016-Present - Deputy Researcher PI: Fudan University Affiliated Obstetrics and Gynecology Hospital

Awards

Shanghai Pujiang Talent Program
Fudan University Zhuoxue Talent Program

Areas of Focus	Molecular genetics and developmental mechanisms of major neurological diseases caused by abnormal early embryonic development
Publications	Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos, Yan L, Yin H, Mi Y, Wu Y, Zheng Y, 2023 High glucose causes developmental abnormalities in neuroepithelial cysts with actin and HK1 distribution changes, Peng S, Wu Y, Zheng Y, 2023 Parental folate deficiency induces birth defects in mice accompanied with increased de novo mutations, Zhao Y#, Chen D#, Tang J, Zheng Y, Qi Ji, Wang H, 2022 MeCP2 duplication causes hyperandrogenism by upregulating LHCGR and downregulating RORα, Wang Y, Wu Y, Zheng Y, Wang H, 2021 Organoids as a new model system to study neural tube defects, Wu Y, Peng S, Zheng Y, 2021 SRPS Associated Protein WDR60 Regulates the Multipolar-to-Bipolar Transition of Migrating Neurons during Cortical Development, Li C, Zheng Y, Zheng Y, Xu Z, 2021 WDR34 mutation from anencephaly patients impaired both SHH and PCP signaling pathways, Yin H, Peng R, Chen Z, Wang H, Zhang T, Zheng Y, 2020 Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling, Xie Y, Ma A, Wang B, Peng R, Jing Y, Wang D, Finnell RH., Qiao B, Wang Y, Wang H, Zheng Y, 2019 MicroRNA-197 controls ADAM10 expression to mediate MeCP2’s role in the differentiation of neuronal progenitors, Wang Y#, Zheng Y#,, Yang S, Yang Z, Zhang L, He Y, Gong X, Liu D, Finnell R.H., Qiu Z, Du Y, Wang H, 2019 Threshold for neural tube defect risk by accumulated singleton loss-of-function variants, Chen Z#, Lei Y#, Zheng Y#, Aguiar-Pulido V, Ross M.E., Peng R, Jin L, Zhang T, Finnell R.H., Wang H, 2018

Areas of Focus

Molecular genetics and developmental mechanisms of major neurological diseases caused by abnormal early embryonic development

Publications

Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos, Yan L, Yin H, Mi Y, Wu Y, Zheng Y*, 2023
High glucose causes developmental abnormalities in neuroepithelial cysts with actin and HK1 distribution changes, Peng S, Wu Y, Zheng Y*, 2023
Parental folate deficiency induces birth defects in mice accompanied with increased de novo mutations, Zhao Y#, Chen D#, Tang J, Zheng Y*, Qi Ji*, Wang H*, 2022
MeCP2 duplication causes hyperandrogenism by upregulating LHCGR and downregulating RORα, Wang Y, Wu Y, Zheng Y*, Wang H*, 2021
Organoids as a new model system to study neural tube defects, Wu Y, Peng S, Zheng Y*, 2021
SRPS Associated Protein WDR60 Regulates the Multipolar-to-Bipolar Transition of Migrating Neurons during Cortical Development, Li C, Zheng Y, Zheng Y*, Xu Z*, 2021
WDR34 mutation from anencephaly patients impaired both SHH and PCP signaling pathways, Yin H, Peng R, Chen Z, Wang H, Zhang T, Zheng Y*, 2020
Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling, Xie Y, Ma A, Wang B, Peng R, Jing Y, Wang D, Finnell RH., Qiao B, Wang Y*, Wang H*, Zheng Y*, 2019
MicroRNA-197 controls ADAM10 expression to mediate MeCP2’s role in the differentiation of neuronal progenitors, Wang Y#, Zheng Y#,*, Yang S, Yang Z, Zhang L, He Y, Gong X, Liu D, Finnell R.H., Qiu Z, Du Y*, Wang H*, 2019
Threshold for neural tube defect risk by accumulated singleton loss-of-function variants, Chen Z#, Lei Y#, Zheng Y#, Aguiar-Pulido V, Ross M.E., Peng R, Jin L, Zhang T*, Finnell R.H.*, Wang H*, 2018

Genetics Development Molecular Biochemistry Animal Models Organoid Models Embryonic Development Neurological Diseases Mechanisms Research

Haiyun Wang - Tongji University

Lei Xue - Tongji University

Peng Yang - Tongji University

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