Areas of Focus
- DNA damage repair, molecular mechanisms of genomic instability and tumor development
Work Experience
- 2015-Present - Shanghai Normal University - Professor
- 2012-2015 - University of Michigan Medical School, Department of Internal Medicine - Research Investigator
- 2007-2012 - University of Michigan Medical School, Department of Internal Medicine - Postdoctoral Fellow
- 2005-2007 - University of Texas Southwestern Medical Center, Department of Molecular Biology - Postdoctoral Fellow
Academic Background & Achievements
- 1999-2005 PhD: Zhejiang University
- 1995-1999 Bachelor: Jiangxi Agricultural University
Publications
- WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription, Zhang, F., and Yu, X., 2011
- The PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response, Zhang, F., Shi, J., Chen, S.H., Bian, C., Yu, X., 2015
- The oligonucleotide/oligosaccharide-binding fold is a Poly(ADP-ribose)-binding domain that mediates DNA damage response, Zhang, F., Chen, Y., Li, M., and Yu, X., 2014
- Poly(ADP-Ribose) Mediates the BRCA2-Dependent Early DNA Damage Response, Zhang, F., Shi, J., Bian, C., Yu, X., 2015
- PALB2 links BRCA1 and BRCA2 in the DNA-damage response, Zhang, F., Ma, J., Wu, J., Ye, L., Xia, B., and Yu, X., 2009
- A core hSSB1-INTS complex participates in DNA damage response, Zhang, F., Ma, T., and Yu, X., 2013
- Integrator3, a partner of single-stranded DNA-binding protein 1, participates in the DNA damage response, Zhang, F., Wu, J., and Yu, X., 2009
Awards
- 2012: American Society of Pediatric Hematology/Oncology Award