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Li Cui
Life Sciences
Shanghai Jiao Tong University
Shanghai
Language: Chinese, English
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Enzyme Activity Stability Substrate Specificity Computational Biology Rational Enzyme Design Non-Natural Substrates Catalytic Efficiency Enzyme-Substrate Recognition Specific Catalytic Functions High-Throughput Screening
Areas of Focus
  • Enzyme Catalysis Function Design Optimization
  • Artificial Synthetic Pathway Combination Design
  • Metabolic Pathway Reprogramming
Work Experience
  • 2006-Present: Shanghai Jiao Tong University, State Key Laboratory of Microbial Metabolism
Academic Background & Achievements
  • 1996-2000: Bachelor of Engineering, China Pharmaceutical University
  • 2001-2006: PhD in Microbiology and Biochemical Pharmacy, China Pharmaceutical University
Publications
  • Molecular Evolution of an Aminotransferase Based on Substrate–Enzyme Binding Energy Analysis for Efficient Valienamine Synthesis, Li Cui et al., 2022
  • A validamycin shunt pathway for valienamine synthesis in engineered Streptomyces hygroscopicus 5008, Li Cui et al., 2020
Awards
  • 2016: First Prize, National College Student Life Science Innovation Experiment Competition (Outstanding Instructor)
  • 2020: First Prize, Fifth National College Student Life Science Innovation Experiment Competition (Outstanding Instructor)
  • 2020: Outstanding Bachelor Thesis Advisor (TOP 1%), Shanghai Jiao Tong University
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