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Li Cui
Life Sciences
Shanghai Jiao Tong University
Shanghai
Language: Chinese, English
Enzyme Activity
Stability
Substrate Selectivity
Catalytic Mechanisms
Computational Biology
Enzyme Design
Amino Transferase
Non-Natural Substrates
Efficiency
Precision
Areas of Focus
- Enzyme catalysis function design optimization
- Artificial synthetic pathway combination design metabolic pathway reprogramming
Work Experience
- 2006.07-present Associate Researcher, State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University
Academic Background & Achievements
- 1996.09-2000.06 Bachelor of Engineering, China Pharmaceutical University
- 2001.09-2006.06 PhD in Microbiology and Biochemical Pharmacy, China Pharmaceutical University
Publications
- Molecular Evolution of an Aminotransferase Based on Substrate–Enzyme Binding Energy Analysis for Efficient Valienamine Synthesis, Li Cui, Anqi Cui, Qitong Li, Lezhou Yang, Hao Liu, Wenguang Shao, Yan Feng, 2022
- A validamycin shunt pathway for valienamine synthesis in engineered Streptomyces hygroscopicus 5008, Cui L, Wei XD, Wang XR, Bai LQ, Lin SJ, Feng Y, 2020
- De Novo Biosynthesis of β-Valienamine in Engineered Streptomyces hygroscopicus 5008, Li Cui, Ying Zhu, Xiaoqing Guan, Zixin Deng, Linquan Bai, Yan Feng, 2016
Awards
- 2016: First Prize, National College Student Life Science Innovation Experiment Competition (Outstanding Instructor)
- 2020: First Prize, Fifth National College Student Life Science Innovation Experiment Competition (Outstanding Instructor)
- 2020: Top 1% Excellent Bachelor Thesis Advisor, Shanghai Jiao Tong University
