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Haiping Zhang
Life Sciences
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Deep Learning
Computational Biology
Drug Screening
Drug Design
Small Molecule
Antibody Design
Enzyme Design
Protein-Drug Interaction
Protein-Protein Interaction
Protein-Nucleic Acid Interaction
Areas of Focus
- Deep Learning and Computational Biology for Drug Screening and Design
Work Experience
- 2018.7-2022.2 - Chinese Academy of Sciences Shenzhen Institute of Advanced Technology - Postdoctoral Researcher and Assistant Researcher
- 2022.2-Present - Chinese Academy of Sciences Shenzhen Institute of Advanced Technology - Associate Researcher
Academic Background & Achievements
- 2016.9-2010.6 Bachelor's Degree in Bioengineering: Jiangxi University of Traditional Chinese Medicine
- 2010.9-2013.6 Master's Degree in Genetics, Bioinformatics: Xiamen University
- 2014.1-2018.6 Ph.D. in Computational Biology: Nanyang Technological University
Publications
- Revolutionizing GPCR-Ligand Predictions: DeepGPCR with experimental Validation for High-Precision Drug Discovery, Haiping Zhang, Hongjie Fan, Jixia Wang, Tao Hou, Konda Mani Saravanan, Wei Xia, Hei Wun Kan, Junxin Li, John Z.H. Zhang, Xinmiao Liang, Yang Chen, 2024
- Deep Learning-Based Construction of a Drug-Like Compound Database and Its Application in Virtual Screening of HsDHODH Inhibitors, Wei Xia, Jin Xiao, Hengwei Bian, Jiajun Zhang, John Z.H., Zhang, Haiping Zhang, 2024
- A deep learning based multi-model approach for predicting drug-like chemical compound's toxicity, Konda Mani Saravanan, Jiang-Fan Wan, Liujiang Dai, Jiajun Zhang, John Z.H. Zhang, Haiping Zhang, 2024
- Advances in Deep Learning Assisted Drug Discovery Methods: A Self-review, Haiping Zhang, Konda Mani Saravanan, 2024
- DeepBindGCN: Integrating Molecular Vector Representation with Graph Convolutional Neural Networks for Protein-Ligand Interaction Prediction, Haiping Zhang, Konda Mani Saravanan, John Z.H. Zhang, 2023
- Deep Learning-Based Bioactive Therapeutic Peptide Generation and Screening, Haiping Zhang, Konda Mani Saravanan, Wei Yanjie, Jiao Yang, Yang Yang, Pan Yi, Wu Xuli, John Z.H. Zhang, 2023
- Validation of Deep Learning-Based DFCNN in Extremely Large-Scale Virtual Screening and Application in Trypsin I Protease Inhibitor Discovery, Haiping Zhang, Lin Xiao, Wei Yanjie, Zhang Huiling, Liao Linbu, Wu Hao, Pan Yi, Wu Xuli, 2022
- Generating and screening de novo compounds against given targets using ultrafast deep learning models as core components, Haiping Zhang, Saravanan Konda Mani, Yang Yang, Wei Yanjie, Yi Pan, John Z.H. Zhang, 2022
- DeepBindBC: A practical deep learning method for identifying native-like protein-ligand complexes in virtual screening, Haiping Zhang, Zhang Tingting, Saravanan Konda Mani, Liao Linbu, Wu Hao, Zhang Haishan, Zhang Huiling, Pan Yi, Wu Xuli, Wei Yanjie, 2022
- An Integrated Deep Learning and Molecular Dynamics Simulation-Based Screening Pipeline Identifies Inhibitors of a New Cancer Drug Target TIPE2, Haiping Zhang, Li Junxin, Saravanan Konda Mani, Wu Hao, Wang Zhichao, Wu Du, Wei Yanjie, Lu Zhen, Chen Youhai H, Wan Xiaochun, Pan Yi, 2021
- On the Conformational Dynamics of β-Amyloid Forming Peptides: A Computational Perspective, Konda Mani Saravanan, Haiping Zhang, Huiling Zhang, Wenhui Xi, Yanjie Wei, 2020
- DeepBindPoc: a deep learning method to rank ligand binding pockets using molecular vector representation, Haiping Zhang, Saravanan Konda Manu, Lin Jinzhi, Liao Linbu, Ng Justin TzeYang, Zhou Jiaxiu, Wei Yanjie, 2020
- Investigating the stability of dengue virus envelope protein dimer using well-tempered metadynamics simulations, Haiping Zhang, Kai Eric L J, Lu Lanyuan, 2020
- Deep Learning Based Drug Screening for Novel Coronavirus 2019-nCov, Haiping Zhang, Yang Yang, Li Junxin, Wang Min, Saravanan Konda Mani, Wei Jinli, Ng Justin TzeYang, Hossain Md Tofazzal, Liu Maoxuan, Zhang Huiling, Ren Xiaohu, Pan Yi, Peng Yin, Shi Yi, Wan Xiaochun, Liu Yingxia, Wei Yanjie, 2020
- A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro, Haiping Zhang, Yang Yang, Li Junxin, Wang Min, Saravanan Konda Mani, Wei Jinli, Ng Justin TzeYang, Hossain Md Tofazzal, Liu Maoxuan, Zhang Huiling, Ren Xiaohu, Pan Yi, Peng Yin, Shi Yi, Wan Xiaochun, Liu Yingxia, Wei Yanjie, 2020
- Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation, Yang Longhe, Ji Chunyan, Li Yitian, Hu Fan, Zhang Fang, Zhang Haiping, Li Long, Ren Jie, Wang Zhaokai, Qiu Yan, 2020
- On the Conformational Dynamics of beta-Amyloid Forming Peptides: A Computational Perspective, Saravanan Konda Mani, Zhang Haiping, Zhang Huiling, Xi Wenhui, Wei Yanjie, 2020
- IVS2vec: A tool of Inverse Virtual Screening based on word2vec and deep learning techniques, Haiping Zhang, Liao Linbu, Cai Yunting, Hu Yuhui, Wang Hao, 2019
- Large-Scale Target Identification of Herbal Medicine Using a Reverse Docking Approach, Haiping Zhang, Pan Jianbo, Wu Xuli, Zuo AiRen, Wei Yanjie, Ji ZhiLiang, 2019
- DeepBindRG: a deep learning based method for estimating effective protein-ligand affinity, Haiping Zhang, Liao Linbu, Saravanan Konda Mani, Yin Peng, Wei Yanjie, 2019
