Professor | Liang Zhou | Asia Growth Partners

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Name	Liang Zhou
Contact Information	zhzliang@smu.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Liang Zhou

Contact Information

zhzliang@smu.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern Medical University
Faculty	Public Health
Academic Background & Achievements	1993/09 - 1997/07 Bachelor's Degree: Hanzhong Normal University, Biology Education 1997/09 - 2000/06 Master's Degree: Sichuan University, Zoology 2005/07 - 2009/09 Doctorate: The Chinese University of Hong Kong, Biology
Work Experience	2000/07 - 2004/08 - Chengdu Huashen Biotechnology Co., Ltd. - Quality Department 2004/09 - 2005/07 - Shenzhen National Biochemical Engineering Technology Development Center - R&D Department 2009/09 - 2011/08 - The Chinese University of Hong Kong, Faculty of Medicine - Research Assistant 2011/09 - 2013/03 - The Chinese University of Hong Kong, Faculty of Medicine - Postdoctoral Fellow 2013/03 - 2019/07 - Southern Medical University, School of Public Health, Department of Radiation Medicine - Associate Professor 2019/07 - 2022/01 - Southern Medical University, School of Public Health, Department of Toxicology - Associate Professor 2022/01 - Present - Southern Medical University, School of Public Health, Department of Toxicology - Professor

University/Lab Affiliation and Title

Southern Medical University

Faculty

Public Health

Academic Background & Achievements

1993/09 - 1997/07 Bachelor's Degree: Hanzhong Normal University, Biology Education
1997/09 - 2000/06 Master's Degree: Sichuan University, Zoology
2005/07 - 2009/09 Doctorate: The Chinese University of Hong Kong, Biology

Work Experience

2000/07 - 2004/08 - Chengdu Huashen Biotechnology Co., Ltd. - Quality Department
2004/09 - 2005/07 - Shenzhen National Biochemical Engineering Technology Development Center - R&D Department
2009/09 - 2011/08 - The Chinese University of Hong Kong, Faculty of Medicine - Research Assistant
2011/09 - 2013/03 - The Chinese University of Hong Kong, Faculty of Medicine - Postdoctoral Fellow
2013/03 - 2019/07 - Southern Medical University, School of Public Health, Department of Radiation Medicine - Associate Professor
2019/07 - 2022/01 - Southern Medical University, School of Public Health, Department of Toxicology - Associate Professor
2022/01 - Present - Southern Medical University, School of Public Health, Department of Toxicology - Professor

Areas of Focus	Molecular Toxicology Mechanisms of Cellular Stress Chemical Toxicology Radiation Toxicology Molecular Toxicology of Tumors
Publications	HOXA9 Inhibits HIF-1α-Mediated Glycolysis through Interacting with CRIP2 to Repress Cutaneous Squamous Cell Carcinoma Development, Zhou L, Wang Y, Zhou M, Zhang Y, Wang P, Li X, Yang J, Wang H, Ding Z, 2018 Linc-YY1 promotes myogenic differentiation and muscle regeneration through an interaction with the transcription factor YY1, Zhou L, Sun K, Zhao Y, Zhang S, Wang X, Li Y, Lu L, Chen X, Chen F, Bao X, Zhu X, Wang L, Tang L, Esteban MA, Wang CC, Jauch R, Sun H, Wang H, 2015 PURPL represses autophagic cell death to promote cutaneous melanoma by modulating ULK1 phosphorylation, Han S, Li X, Wang K, Zhu DH#, Meng BY, Liu JY, Liang XT, Jin Y, Liu XY, Wen Q, Zhou L, 2021 MALAT1-KTN1-EGFR regulatory axis promotes the development of cutaneous squamous cell carcinoma, Zhang Y, Gao L, Ma S, Ma J, Wang Y, Li S, Hu X, Han S, Zhou M, Zhou L, Ding Z, 2019 HOXA9 Transcriptionally Promotes Apoptosis and Represses Autophagy by Targeting NF-κB in Cutaneous Squamous Cell Carcinoma, Han S, Li X, Liang X, Zhou L, 2019 Loss of BAX by miR-365 Promotes Cutaneous Squamous Cell Carcinoma Progression by Suppressing Apoptosis, Zhou L, Gao R, Wang Y, Zhou M, Ding Z, 2017 microRNA-365-targeted nuclear factor I/B transcriptionally represses cyclin-dependent kinase 6 and 4 to inhibit the progression of cutaneous squamous cell carcinoma, Zhou L, Wang Y, Ou C, Lin Z, Wang J, Liu H, Zhou M, Ding Z, 2015 A novel target of microRNA-29, Ring1 and YY1-binding protein (Rybp), negatively regulates skeletal myogenesis, Zhou L, Wang LJ, Lu LN, Jiang PY, Sun Hao, Wang HT, 2012 Inhibition of miR-29 by TGF-beta-Smad3 signaling through dual mechanisms promotes transdifferentiation of mouse myoblasts into myofibroblasts, Zhou L, Wang LJ, Lu LN, Jiang PY, Sun Hao, Wang HT, 2012 Paraformaldehyde Fixation May Lead to Misinterpretation of the Subcellular Localization of Plant High Mobility Group Box Proteins, Li MW#, Zhou L#, Lam HM, 2015 Rice hypersensitive induced reaction protein 1 (OsHIR1) associates with plasma membrane and triggers hypersensitive cell death, Zhou L, Cheung MY, Li MW, Fu YP, Sun ZX, Sun SS, Lam HM, 2010 A novel simple extracellular leucine-rich repeat (eLRR) domain protein from rice (OsLRR1) enters the endosomal pathway and interacts with the hypersensitive-induced reaction protein 1 (OsHIR1), Zhou L, Cheung MY, Zhang Q, Lei CL, Zhang SH, Sun SS, Lam HM*, 2009

Areas of Focus

Molecular Toxicology Mechanisms of Cellular Stress
Chemical Toxicology
Radiation Toxicology
Molecular Toxicology of Tumors

Publications

HOXA9 Inhibits HIF-1α-Mediated Glycolysis through Interacting with CRIP2 to Repress Cutaneous Squamous Cell Carcinoma Development, Zhou L, Wang Y, Zhou M, Zhang Y, Wang P, Li X, Yang J, Wang H, Ding Z*, 2018
Linc-YY1 promotes myogenic differentiation and muscle regeneration through an interaction with the transcription factor YY1, Zhou L, Sun K, Zhao Y, Zhang S, Wang X, Li Y, Lu L, Chen X, Chen F, Bao X, Zhu X, Wang L, Tang L, Esteban MA, Wang CC, Jauch R, Sun H*, Wang H*, 2015
PURPL represses autophagic cell death to promote cutaneous melanoma by modulating ULK1 phosphorylation, Han S, Li X, Wang K, Zhu DH#, Meng BY, Liu JY, Liang XT, Jin Y, Liu XY, Wen Q*, Zhou L*, 2021
MALAT1-KTN1-EGFR regulatory axis promotes the development of cutaneous squamous cell carcinoma, Zhang Y, Gao L, Ma S, Ma J, Wang Y, Li S, Hu X, Han S, Zhou M, Zhou L*, Ding Z*, 2019
HOXA9 Transcriptionally Promotes Apoptosis and Represses Autophagy by Targeting NF-κB in Cutaneous Squamous Cell Carcinoma, Han S, Li X, Liang X, Zhou L*, 2019
Loss of BAX by miR-365 Promotes Cutaneous Squamous Cell Carcinoma Progression by Suppressing Apoptosis, Zhou L, Gao R, Wang Y, Zhou M, Ding Z*, 2017
microRNA-365-targeted nuclear factor I/B transcriptionally represses cyclin-dependent kinase 6 and 4 to inhibit the progression of cutaneous squamous cell carcinoma, Zhou L, Wang Y, Ou C, Lin Z, Wang J, Liu H, Zhou M, Ding Z*, 2015
A novel target of microRNA-29, Ring1 and YY1-binding protein (Rybp), negatively regulates skeletal myogenesis, Zhou L, Wang LJ, Lu LN, Jiang PY, Sun Hao*, Wang HT*, 2012
Inhibition of miR-29 by TGF-beta-Smad3 signaling through dual mechanisms promotes transdifferentiation of mouse myoblasts into myofibroblasts, Zhou L, Wang LJ, Lu LN, Jiang PY, Sun Hao*, Wang HT*, 2012
Paraformaldehyde Fixation May Lead to Misinterpretation of the Subcellular Localization of Plant High Mobility Group Box Proteins, Li MW#, Zhou L#, Lam HM*, 2015
Rice hypersensitive induced reaction protein 1 (OsHIR1) associates with plasma membrane and triggers hypersensitive cell death, Zhou L, Cheung MY, Li MW, Fu YP, Sun ZX, Sun SS, Lam HM*, 2010
A novel simple extracellular leucine-rich repeat (eLRR) domain protein from rice (OsLRR1) enters the endosomal pathway and interacts with the hypersensitive-induced reaction protein 1 (OsHIR1), Zhou L, Cheung MY, Zhang Q, Lei CL, Zhang SH, Sun SS, Lam HM*, 2009

Lncrna Mirna Epigenetic Regulation Cell Apoptosis Autophagy Endoplasmic Reticulum Stress Hypoxia Stress Glucose Metabolism Emt Signal Transduction Pathways

Guodong Lu - Fudan University

Jinbao Gu - Southern Medical University

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