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Guodong Lu
Public Health
Fudan University
Shanghai
Language: Chinese, English
Glucose Metabolism
Lipid Metabolism
Tumor Cells
Cell Growth
Cell Death
Liver Cancer
Ischemia
Fat Metabolism
Autophagy
Mitochondrial Homeostasis
Lipid Peroxidation
Lysosomal Activity
Ferroptosis
Iron
Reduction Dysfunction
Iron Autophagy
Pharmacology
Neuroprotection
Cancer Therapy
C. Elegans
Aging
Toxicology
Model Organism
Aging Mechanisms
Aging Prevention
Toxic Substances
Aging Susceptibility
Research
Areas of Focus
- Impact of Glucose and Lipid Metabolism on Tumor Cell Growth and Death
- Lipid Peroxidation, Lysosomal Activity, and Ferroptosis
- Pharmacology and Toxicology Research Using C. elegans Model Organism
Publications
- Pharmacological approaches for targeting lysosomes to induce ferroptotic cell death in cancer, Feng J, et al., 2024
- Andrographolide causes p53-independent HCC cell death through p62 accumulation and impaired DNA damage repair, Li XY, et al., 2023
- Quercetin induces p53-independent cancer cell death through TFEB-mediated lysosome activation and ROS-dependent ferroptosis, Wang ZX, et al., 2021
Awards
- Guangxi Science and Technology Award for Natural Science (2023): Second Prize, ranked second
