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Zhimin Lu
Medical School
Zhejiang University
Zhejiang
Language: English, Chinese
Cancer
Metabolism
Tumor
Cell Signaling
Protein Kinase
Phosphorylation
Warburg Effect
Enzyme Function
Gene Expression
Tumor Diagnosis
Areas of Focus
- Tumor Metabolism
- Tumorigenesis and Development
Work Experience
- 2022—Present Vice Dean: Zhejiang University School of Medicine
- 2019—Present Director: Zhejiang University Institute of Translational Medicine
- 2019—Present Kuancheng Wang Distinguished Chair Professor: Zhejiang University
- 2015—2018 Director: Center for Cancer Metabolism, University of Texas MD Anderson Cancer Center
- 2015—2018 Ruby E. Rutherford Distinguished Professor: University of Texas MD Anderson Cancer Center
- 2013—2018 Professor of Neuro-Oncology (Tenured): University of Texas MD Anderson Cancer Center
- 2009—2013 Associate Professor of Neuro-Oncology (Tenured): University of Texas MD Anderson Cancer Center
- 2003—2009 Assistant Professor of Neuro-Oncology: University of Texas MD Anderson Cancer Center
Academic Background & Achievements
- 1999—2003 Research Assistant/Postdoctoral Fellow: Salk Institute for Biological Studies
- 1998 Ph.D. in Molecular, Cellular, and Developmental Biology: City University of New York
- 1986 Bachelor's in Clinical Medicine: Taishan Medical University
Publications
- Phosphorylation of histone H3 by PKM2 regulates gene expression, Zhimin Lu, 2012
- Fructokinase A (KHK-A) phosphorylates and activates PRPS1 to promote nucleic acid synthesis and liver cancer formation, Zhimin Lu, 2016
- PGK1 phosphorylates Beclin1 to induce autophagy under energy stress, Zhimin Lu, 2017
- PCK1 phosphorylation of INSIG activates SREBP and tumor lipogenesis, Zhimin Lu, 2020
- CHKα2 phosphorylation of PLIN2/3 promotes lipolysis in lipid droplets, Zhimin Lu, 2021
- HK2 phosphorylation of IκBα promotes PD-L1 expression and tumor immune evasion, Zhimin Lu, 2022
- CKB phosphorylation of GPX4 inhibits ferroptosis, Zhimin Lu, 2023
Awards
- 2022 Chinese Medical Science Award: International Scientific and Technological Cooperation Award
- 2022 WuXi AppTec Life Chemistry Research Award: Outstanding Achievement Award
- 2021 Foreign Member: Academia Europaea (The Academy of Europe)
- 2019 Kuancheng Wang Distinguished Chair Professor: Zhejiang University
- 2017 Fellow: American Association for the Advancement of Science
- 2016 Dallas/Fort Worth Living Legend Basic Research Achievement Award: University of Texas MD Anderson Cancer Center
- 2015 Science and Technology Acquisition and Retention (STARs) Award: University of Texas
- 2015 Ruby E. Rutherford Distinguished Professor: University of Texas MD Anderson Cancer Center
- 2013 Potu N. Rao Excellence in Basic Science Award: University of Texas MD Anderson Cancer Center
- 2012 James S. McDonnell Foundation Scholar Award
- 2011 Faculty Scholar Award: University of Texas MD Anderson Cancer Center
- 2009 Research Scholar Award: American Cancer Society
- 2008 Peter Steck Young Investigator Award
- 2000 Postdoctoral Fellowship: California Breast Cancer Research Program
- 1999 Pioneer Fund Fellowship: Salk Institute
- 1997 Beatrice Goldstein Konheim Graduate Fellowship: Hunter College, City University of New York
