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Xin Sheng
Medical School
Zhejiang University
Zhejiang
Language: Chinese, English
Genetics
Disease Mechanisms
Bioinformatics
Multi-Omics
Single Cell
Algorithm Development
Molecular Biology
Genetic Variation
Gene Expression
Eqtl
Areas of Focus
- Medical Genetics
- Bioinformatics
- Multi-Omics Integration Analysis
- Single Cell
Work Experience
- 2017.11-2021.7 - University of Pennsylvania, Perelman School of Medicine - Postdoctoral Researcher, Supervisor: Dr. Katalin Susztak
- 2021.9-Present - Zhejiang University Medical Center - Researcher
Academic Background & Achievements
- 2007.9-2012.6 Bachelor's Degree: Harbin Medical University, Bioinformatics
- 2012.9-2017.7 Doctorate: Beijing Institute of Genomics, Chinese Academy of Sciences, Bioinformatics, Supervisors: Researcher Jun Yu and Researcher Jingfa Xiao
- Published 29 papers in top journals such as Nature Genetics, Cell Metabolism, Science Translational Medicine, PNAS
- Cumulative impact factor over 460
- Cited over 1700 times in the past five years by journals like Cell, Nature, New England Journal of Medicine
- 19 highly cited papers (h-index=19, i10-index=24)
- Published 7 first-author or corresponding-author papers
Publications
- Overcoming the challenges of high cellular heterogeneity in kidney by developing an original algorithm to analyze genetic variation (SNP) effects on gene expression at the single-cell level, Xin Sheng, 2021
- Identifying key genetic factors affecting inflammation response leading to kidney damage through Bayesian multi-trait colocalization analysis and Mendelian randomization algorithm, Xin Sheng, 2020
- Identifying new CKD pathogenic gene MANBA and its pathogenic SNP through Bayesian colocalization analysis and fine mapping algorithm, Xin Sheng, 2021
Awards
- West Lake Pearl Project Overseas High-Level Talent Program Technology Innovation Talent-Youth Special Funding
