Professor | Jian Zou | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Jian Zou
Contact Information	jianzou@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

Upload Avatar (500 x 500)

Name

Jian Zou

Contact Information

jianzou@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	1994-1998 Bachelor: Sichuan University, Biochemistry 1998-2003 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Biochemistry and Molecular Biology
Work Experience	2003.9-2004.3 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Research Assistant 2004.4-2013.1 - University of Pittsburgh, Department of Ophthalmology - Postdoctoral Fellow and Research Assistant 2013.2-2014.2 - Northwestern University, Department of Neurology - Research Assistant 2014.3-present - Zhejiang University School of Medicine, Institute of Translational Medicine and Second Affiliated Hospital - Professor

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

1994-1998 Bachelor: Sichuan University, Biochemistry
1998-2003 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Biochemistry and Molecular Biology

Work Experience

2003.9-2004.3 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Research Assistant
2004.4-2013.1 - University of Pittsburgh, Department of Ophthalmology - Postdoctoral Fellow and Research Assistant
2013.2-2014.2 - Northwestern University, Department of Neurology - Research Assistant
2014.3-present - Zhejiang University School of Medicine, Institute of Translational Medicine and Second Affiliated Hospital - Professor

Areas of Focus	Retinal photoreceptor cell death mechanisms and potential interventions Mechanisms of retinal progenitor cell pluripotency exit and lineage differentiation Mechanisms of retinal photoreceptor cell organization and formation Mechanisms of cellular polarity establishment, maintenance, and dynamic regulation
Publications	Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade, Zhang Q, Meng F, Chen S, Plouffe SW, Wu S, Liu S, Li X, Zhou R, Wang J, Zhao B, Liu J, Qin J, Zou J, Feng XH, Guan KL, Xu P, 2017 PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1, Xiang W, Zhang Q, Lin X, Wu S, Zhou Y, Meng F, Fan Y, Shen T, Xiao M, Xia Z, Zou J, Feng XH, Xu P, 2016 Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation, Meng F, Zhou R, Wu S, Zhang Q, Jin Q, Zhou Y, Plouffe SW, Liu S, Song H, Xia Z, Zhao B, Ye S, Feng XH, Guan KL, Zou J, Xu P, 2016 Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish, Liu F, Chen J, Yu S, Raghupathy R, Liu X, Qin Y, Li C, Huang M, Liao S, Wang J, Zou J, Shu X, Tang Z, Liu M, 2015 Defining midbrain dopaminergic neuron diversity by single-cell gene expression profiling, Poulin JF, Zou J, Drouin-Ouellet J, Kim KY, Cicchetti F, Awatramani RB, 2014 Spatial-temporal expressions of Crumbs and Nagie oko and their interdependence in zebrafish central nervous system during early development, Zou, J, Wen, Y, Yang, X, and Wei, X, 2013 Characterization of transgenic zebrafish lines that express GFP in the retina, pineal gland, olfactory bulb, hatching gland, and optic tectum, Fang, W, Bonaffini, S, Zou, J, Wang, X, Zhang, C, Tsujimura, T, Kawamura, S, and Wei, X, 2013 Crb apical polarity proteins maintain zebrafish retinal cone mosaics via intercellular binding of their extracellular domains, Zou, J, Wang, X, and Wei, X, 2012 Restricted localization of ponli, a novel zebrafish MAGUK-family protein, to the inner segment interface areas between green, red, and blue cones, Zou, J, Yang, X, and Wei, X, 2010 Stepwise maturation of apicobasal polarity of the neuroepithelium is essential for vertebrate neurulation, Yang, X, Zou, J, Hyde, DR, Davidson, LA, and Wei, X, 2009 Intact retinal pigment epithelium maintained by Nok is essential for retinal epithelial polarity and cellular patterning in zebrafish, Zou, J, Lathrop, KL, Sun, M, and Wei, X, 2008 The Fugu tyrp1 promoter directs specific GFP expression in zebrafish: tools to study the RPE and the neural crest-derived melanophores, Zou J, Beermann F, Wang J, Kawakami K, Wei X, 2006

Areas of Focus

Retinal photoreceptor cell death mechanisms and potential interventions
Mechanisms of retinal progenitor cell pluripotency exit and lineage differentiation
Mechanisms of retinal photoreceptor cell organization and formation
Mechanisms of cellular polarity establishment, maintenance, and dynamic regulation

Publications

Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade, Zhang Q, Meng F, Chen S, Plouffe SW, Wu S, Liu S, Li X, Zhou R, Wang J, Zhao B, Liu J, Qin J, Zou J, Feng XH, Guan KL, Xu P, 2017
PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1, Xiang W, Zhang Q, Lin X, Wu S, Zhou Y, Meng F, Fan Y, Shen T, Xiao M, Xia Z, Zou J, Feng XH, Xu P, 2016
Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation, Meng F, Zhou R, Wu S, Zhang Q, Jin Q, Zhou Y, Plouffe SW, Liu S, Song H, Xia Z, Zhao B, Ye S, Feng XH, Guan KL, Zou J, Xu P, 2016
Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish, Liu F, Chen J, Yu S, Raghupathy R, Liu X, Qin Y, Li C, Huang M, Liao S, Wang J, Zou J, Shu X, Tang Z, Liu M, 2015
Defining midbrain dopaminergic neuron diversity by single-cell gene expression profiling, Poulin JF, Zou J, Drouin-Ouellet J, Kim KY, Cicchetti F, Awatramani RB, 2014
Spatial-temporal expressions of Crumbs and Nagie oko and their interdependence in zebrafish central nervous system during early development, Zou, J, Wen, Y, Yang, X, and Wei, X, 2013
Characterization of transgenic zebrafish lines that express GFP in the retina, pineal gland, olfactory bulb, hatching gland, and optic tectum, Fang, W, Bonaffini, S, Zou, J, Wang, X, Zhang, C, Tsujimura, T, Kawamura, S, and Wei, X, 2013
Crb apical polarity proteins maintain zebrafish retinal cone mosaics via intercellular binding of their extracellular domains, Zou, J, Wang, X, and Wei, X, 2012
Restricted localization of ponli, a novel zebrafish MAGUK-family protein, to the inner segment interface areas between green, red, and blue cones, Zou, J, Yang, X, and Wei, X, 2010
Stepwise maturation of apicobasal polarity of the neuroepithelium is essential for vertebrate neurulation, Yang, X, Zou, J, Hyde, DR, Davidson, LA, and Wei, X, 2009
Intact retinal pigment epithelium maintained by Nok is essential for retinal epithelial polarity and cellular patterning in zebrafish, Zou, J, Lathrop, KL, Sun, M, and Wei, X, 2008
The Fugu tyrp1 promoter directs specific GFP expression in zebrafish: tools to study the RPE and the neural crest-derived melanophores, Zou J, Beermann F, Wang J, Kawakami K, Wei X, 2006

Photoreceptors Cell Death Interventions Retinal Progenitor Cells Pluripotency Lineage Differentiation Cell Organization Formation Cellular Polarity Regulation

Juan Lin - Xiamen University

Zhanghua Yang - Xiamen University

Yafei Yin - Zhejiang University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us