Professor | Longguang Tang | Asia Growth Partners

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Name	Longguang Tang
Contact Information	tanglongguang@zju.edu.cn
Language ability	English, Chinese
Province	Zhejiang

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Name

Longguang Tang

Contact Information

tanglongguang@zju.edu.cn

Language ability

English, Chinese

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	PhD: Xiamen University - NIH Joint Program Postdoc: Stanford University Developed targeted small molecules and nano delivery systems for cancer and brain injury Published over 50 SCI papers, 30 as first/corresponding author 7 authorized national invention patents
Work Experience	Researcher, Doctoral Supervisor - Zhejiang University Vice Editor - Nano TransMed Youth Editorial Board Member - Research, Asian Journal of Pharmaceutical Sciences, VIEW
Awards	Alavi–Mandell Award: American Society of Nuclear Medicine and Molecular Imaging

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

PhD: Xiamen University - NIH Joint Program
Postdoc: Stanford University
Developed targeted small molecules and nano delivery systems for cancer and brain injury
Published over 50 SCI papers, 30 as first/corresponding author
7 authorized national invention patents

Work Experience

Researcher, Doctoral Supervisor - Zhejiang University
Vice Editor - Nano TransMed
Youth Editorial Board Member - Research, Asian Journal of Pharmaceutical Sciences, VIEW

Awards

Alavi–Mandell Award: American Society of Nuclear Medicine and Molecular Imaging

Areas of Focus	Drug Delivery Lysosome-Targeted Protein Degradation Molecular Imaging Probes
Publications	A DNA origami device spatially controls CD95 signalling to induce immune tolerance in rheumatoid arthritis, Ling Li, Jue Yin, Wen Ma, Longguang Tang, Jianhua Zou, Linzi Yang, Ting Du, Yi Zhao, Lianhui Wang, Zhen Yang, Chunhai Fan, Jie Chao, Xiaoyuan Chen, 2024 Neutrophil Targeting Platform Reduces Neutrophil Extracellular Traps for Improved Traumatic Brain Injury and Stroke Theranostics, Mu Q, Yao K, Syeda MZ, Wan J, Cheng Q, You Z, Sun R, Zhang Y, Zhang H, Lu Y, Luo Z, Li Y, Liu F, Liu H, Zou X, Zhu Y, Peng K, Huang C, Chen X, Tang L, 2024 Targeting Neutrophils for Enhanced Cancer Theranostics, Longguang Tang, Zhantong Wang, Qingchun Mu, Zhiqiang Yu, Orit Jacobson, Ling Li, Weijing Yang, Chunming Huang, Fei Kang, Wenpei Fan, Ying Ma, Maosheng Wang, Zijian Zhou, Xiaoyuan Chen, 2020 Bioactivable Sting Nanoagonists to Synergize Nir-Ii Mild Photothermal Therapy Primed Robust and Long-Term Anticancer Immunity, Wen Ma, Rui Sun, Longguang Tang, Zibo Li, Ling Lin, Ziyi Mai, Gui Chen, Zhiqiang Yu, 2023 Hesperetin nanoparticle targeting neutrophils for enhanced TBI therapy, Kai Yao, Qingchun Mu, Yufei Zhang, Qian Cheng, Xiaozhi Cheng, Xiaojing Liu, Chunmei Luo, Chumei Li, Shuxia Cai, Zhicheng Luo, Xiulong Zhu, Xiangtong Zhang, Liao Cui, Chunming Huang, Longguang Tang, 2022 Ligustrazine Nanoparticle Hitchhiking On Neutrophils For Enhanced Therapy Of Cerebral Ischemia-Reperfusion Injury, Qingchun Mu, Kai Yao, Madiha Zahra Syeda, Min Zhang, Qian Cheng, Yufei Zhang, Rui Sun, Yuting Lu, Huamiao Zhang, Zhicheng Luo, Hanning Huang, Xiaojing Liu, Chunmei Luo, Xiulong Zhu, Shuyu Wu, Liao Cui, Chunming Huang, Xiaoyuan Chen, Longguang Tang, 2023 Ferroptosis Detection: From Approaches to Applications, Fantian Zeng, Sureya Nijiati, Longguang Tang, Jinmin Ye, Zijian Zhou, Xiaoyuan Chen, 2023 Coordinating the mechanism of actions of ferroptosis and photothermal effect for cancer theranostics, Fantian Zeng, Longguang Tang, Qianyu Zhang, Changrong Shi, Zicheng Huang, Sureya Nijiati, Xiaoyuan Chen, Zijian Zhou, 2021 A Prodrug nanoplatform via esterification of STING agonist and IDO inhibitor for synergistic cancer immunotherapy, Madiha Zahra Syeda, Tu Hong, Min Zhang, Yanfei Han, Xiaoling Zhu, Songmin Ying, Longguang Tang, 2022 LAT1 Targeted Brain Delivery of Temozolomide and Sorafenib for Effective Glioma Therapy, Yufei Zhang, Qian Cheng, Yuhao Xue, Kai Yao, Madiha Zahra Syeda, Jian Xu, Jianheng Wu, Zhenjie Wang, Longguang Tang, Qingchun Mu, 2023 pH-activated nanoplatform for visualized photodynamic and ferroptosis synergistic therapy of tumors, Rui Sun, Wen Ma, Mingjian Ling, Chenhong Tang, Min Zhong, Jingyue Dai, Meiyan Zhu, Xuzi Cai, Guang Li, Qing Xu, Longguang Tang, Zhiqiang Yu, Zhenwei Peng, 2022 Nanodevices for deep cartilage penetration, Xiao-Ling Xu, Yan Xue, Jia-Ying Ding, Zhi-Heng Zhu, Xi-Chen Wu, Yong-Jia Song, Yue-Long Cao, Long-Guang Tang, Dao-Fang Ding, Jian-Guang Xu, 2022 Recent advances of bioresponsive polymeric nanomedicine for cancer therapy, Tu Hong, Xinyuan Shen, Madiha Zahra Syeda, Yang Zhang, Haonan Sheng, Yipeng Zhou, JinMing Xu, Chaojie Zhu, Hongjun Li, Zhen Gu, Longguang Tang, 2022 Delivery of triptolide: a combination of traditional Chinese medicine and nanomedicine, Rui Sun, Jingyue Dai, Mingjian Ling, Ling Yu, Zhiqiang Yu, Longguang Tang, 2022 Smart NIR-II croconaine dye-peptide for enhanced photo-sonotheranostics of hepatocellular carcinoma, Shuang Li, Yang Zhang, Xue Liu, Ye Tian, Yi Cheng, Longguang Tang, Huirong Lin, 2022 Croconaine Nanoparticles with Enhanced Tumor Accumulation for Multimodality Cancer Theranostic, Longguang Tang, Fuwu Zhang, Fei Yu, Wenjing Sun, Menglin Song, Xiaoyuan Chen, Xianzhong Zhang, Xiaolian Sun, 2017 A logic-gated modular nanovesicle enables programmable drug release for on-demand chemotherapy, Longguang Tang, Zhen Yang, Zijian Zhou, Ying Ma, Dale O. Kiesewetter, Zhantong Wang, Wenpei Fan, Shoujun Zhu, Mingru Zhang, Rui Tian, Lixin Lang, Gang Niu, Xianzhong Zhang, Xiaoyuan Chen, 2019 Radioiodinated Small-Molecule Tyrosine Kinase Inhibitor for HER2-Selective SPECT Imaging, Longguang Tang, Chenyu Peng, Bowen Tang, Zijing Li, Xiangyu Wang, Jindian Li, Fei Gao, Lumei Huang, Duo Xu, Pu Zhang, Rongqiang Zhuang, Xinhui Su, Xiaoyuan Chen, Xianzhong Zhang, 2018 Tumor Microenvironment-Activated Ratiometric Photoacoustic Nanoprobes for Specific Ultrasensitive Detection of Intratumoral Glutathione, Longguang Tang, Fei yu, Bowen Tang, Wenpei Fan, Mingru Zhang, Zhantong Wang, Zhen Yang, Orit Jacobson, Zijian Zhou, Ling Li, Yijing Liu, Dale O. Kiesewetter, Wei Tang, Liangcan He, Ying Ma, Gang Niu, Xianzhong Zhang, Xiaoyuan Chen, 2019 NIR-II emissive dye based polymer nanoparticle targeting EGFR for oral cancer theranostics, Mingjian Ling, Rui Sun, Guang Li, Madiha Zahra Syeda, Wen Ma, Ziyi Mai, Longquan Shao, Longguang Tang, Zhiqiang Yu, 2022 Long-term live-cell lipid droplet-targeted biosensor development for nanoscopic tracking of lipid droplet-mitochondria contact sites, Chengying Zhang, Huarong Shao, Xinyan Guo, Yue Liu, Jie Zhang, Zhigang Song, Fei Liu, Peixue Ling, Longguang Tang, KangNan Wang, Qixin Chen, 2021 Design, synthesis and structure-activity relationship study of novel indole-2-carboxamide derivatives as anti-inflammatory agents for the treatment of sepsis, Zhiguo Liu, Longguang Tang, Heping Zhu, Tingting Xu, Chenyu Qiu, Suqing Zheng, Yugui Gu, Jianpeng Feng, Yali Zhang, Guang Liang, 2016 Recent developments in mesoporous polydopamine-derived nanoplatforms for cancer theranostics, Zhu M, Shi Y, Shan Y, Guo J, Song X, Wu Y, Wu M, Lu Y, Chen W, Xu X, Tang L, 2021 Radiolabeled Angiogenesis-Targeting Croconaine Nanoparticles for Trimodality Imaging Guided Photothermal Therapy of Glioma, Longguang Tang, Xiaoli Sun, Nian Liu, Zijian Zhou, Fei Yu, Xianzhong Zhang, Xiaolian Sun, Xiaoyuan Chen, 2018 Redox-responsive dual chemophotothermal therapeutic nanomedicine for imaging-guided combinational therapy, Fei Yu, Fuwu Zhang, Longguang Tang, Jingwen Ma, Daishun Ling, Xiaoyuan Chen, Xiaolian Sun, 2018 Synthesis and biological evaluation of allylated and prenylated mono-carbonyl analogues of curcumin as anti-inflammatory agents, Zhiguo Liu, Longguang Tang, Peng Zou, Yali Zhang, Zhe Wang, Qilu Fang, Lili Jiang, Gaozhi Chen, Zheng Xu, Guang Liang, 2014

Areas of Focus

Drug Delivery
Lysosome-Targeted Protein Degradation
Molecular Imaging Probes

Publications

A DNA origami device spatially controls CD95 signalling to induce immune tolerance in rheumatoid arthritis, Ling Li, Jue Yin, Wen Ma, Longguang Tang, Jianhua Zou, Linzi Yang, Ting Du, Yi Zhao, Lianhui Wang, Zhen Yang, Chunhai Fan, Jie Chao, Xiaoyuan Chen, 2024
Neutrophil Targeting Platform Reduces Neutrophil Extracellular Traps for Improved Traumatic Brain Injury and Stroke Theranostics, Mu Q, Yao K, Syeda MZ, Wan J, Cheng Q, You Z, Sun R, Zhang Y, Zhang H, Lu Y, Luo Z, Li Y, Liu F, Liu H, Zou X, Zhu Y, Peng K, Huang C, Chen X, Tang L, 2024
Targeting Neutrophils for Enhanced Cancer Theranostics, Longguang Tang, Zhantong Wang, Qingchun Mu, Zhiqiang Yu, Orit Jacobson, Ling Li, Weijing Yang, Chunming Huang, Fei Kang, Wenpei Fan, Ying Ma, Maosheng Wang, Zijian Zhou, Xiaoyuan Chen, 2020
Bioactivable Sting Nanoagonists to Synergize Nir-Ii Mild Photothermal Therapy Primed Robust and Long-Term Anticancer Immunity, Wen Ma, Rui Sun, Longguang Tang, Zibo Li, Ling Lin, Ziyi Mai, Gui Chen, Zhiqiang Yu, 2023
Hesperetin nanoparticle targeting neutrophils for enhanced TBI therapy, Kai Yao, Qingchun Mu, Yufei Zhang, Qian Cheng, Xiaozhi Cheng, Xiaojing Liu, Chunmei Luo, Chumei Li, Shuxia Cai, Zhicheng Luo, Xiulong Zhu, Xiangtong Zhang, Liao Cui, Chunming Huang, Longguang Tang, 2022
Ligustrazine Nanoparticle Hitchhiking On Neutrophils For Enhanced Therapy Of Cerebral Ischemia-Reperfusion Injury, Qingchun Mu, Kai Yao, Madiha Zahra Syeda, Min Zhang, Qian Cheng, Yufei Zhang, Rui Sun, Yuting Lu, Huamiao Zhang, Zhicheng Luo, Hanning Huang, Xiaojing Liu, Chunmei Luo, Xiulong Zhu, Shuyu Wu, Liao Cui, Chunming Huang, Xiaoyuan Chen, Longguang Tang, 2023
Ferroptosis Detection: From Approaches to Applications, Fantian Zeng, Sureya Nijiati, Longguang Tang, Jinmin Ye, Zijian Zhou, Xiaoyuan Chen, 2023
Coordinating the mechanism of actions of ferroptosis and photothermal effect for cancer theranostics, Fantian Zeng, Longguang Tang, Qianyu Zhang, Changrong Shi, Zicheng Huang, Sureya Nijiati, Xiaoyuan Chen, Zijian Zhou, 2021
A Prodrug nanoplatform via esterification of STING agonist and IDO inhibitor for synergistic cancer immunotherapy, Madiha Zahra Syeda, Tu Hong, Min Zhang, Yanfei Han, Xiaoling Zhu, Songmin Ying, Longguang Tang, 2022
LAT1 Targeted Brain Delivery of Temozolomide and Sorafenib for Effective Glioma Therapy, Yufei Zhang, Qian Cheng, Yuhao Xue, Kai Yao, Madiha Zahra Syeda, Jian Xu, Jianheng Wu, Zhenjie Wang, Longguang Tang, Qingchun Mu, 2023
pH-activated nanoplatform for visualized photodynamic and ferroptosis synergistic therapy of tumors, Rui Sun, Wen Ma, Mingjian Ling, Chenhong Tang, Min Zhong, Jingyue Dai, Meiyan Zhu, Xuzi Cai, Guang Li, Qing Xu, Longguang Tang, Zhiqiang Yu, Zhenwei Peng, 2022
Nanodevices for deep cartilage penetration, Xiao-Ling Xu, Yan Xue, Jia-Ying Ding, Zhi-Heng Zhu, Xi-Chen Wu, Yong-Jia Song, Yue-Long Cao, Long-Guang Tang, Dao-Fang Ding, Jian-Guang Xu, 2022
Recent advances of bioresponsive polymeric nanomedicine for cancer therapy, Tu Hong, Xinyuan Shen, Madiha Zahra Syeda, Yang Zhang, Haonan Sheng, Yipeng Zhou, JinMing Xu, Chaojie Zhu, Hongjun Li, Zhen Gu, Longguang Tang, 2022
Delivery of triptolide: a combination of traditional Chinese medicine and nanomedicine, Rui Sun, Jingyue Dai, Mingjian Ling, Ling Yu, Zhiqiang Yu, Longguang Tang, 2022
Smart NIR-II croconaine dye-peptide for enhanced photo-sonotheranostics of hepatocellular carcinoma, Shuang Li, Yang Zhang, Xue Liu, Ye Tian, Yi Cheng, Longguang Tang, Huirong Lin, 2022
Croconaine Nanoparticles with Enhanced Tumor Accumulation for Multimodality Cancer Theranostic, Longguang Tang, Fuwu Zhang, Fei Yu, Wenjing Sun, Menglin Song, Xiaoyuan Chen, Xianzhong Zhang, Xiaolian Sun, 2017
A logic-gated modular nanovesicle enables programmable drug release for on-demand chemotherapy, Longguang Tang, Zhen Yang, Zijian Zhou, Ying Ma, Dale O. Kiesewetter, Zhantong Wang, Wenpei Fan, Shoujun Zhu, Mingru Zhang, Rui Tian, Lixin Lang, Gang Niu, Xianzhong Zhang, Xiaoyuan Chen, 2019
Radioiodinated Small-Molecule Tyrosine Kinase Inhibitor for HER2-Selective SPECT Imaging, Longguang Tang, Chenyu Peng, Bowen Tang, Zijing Li, Xiangyu Wang, Jindian Li, Fei Gao, Lumei Huang, Duo Xu, Pu Zhang, Rongqiang Zhuang, Xinhui Su, Xiaoyuan Chen, Xianzhong Zhang, 2018
Tumor Microenvironment-Activated Ratiometric Photoacoustic Nanoprobes for Specific Ultrasensitive Detection of Intratumoral Glutathione, Longguang Tang, Fei yu, Bowen Tang, Wenpei Fan, Mingru Zhang, Zhantong Wang, Zhen Yang, Orit Jacobson, Zijian Zhou, Ling Li, Yijing Liu, Dale O. Kiesewetter, Wei Tang, Liangcan He, Ying Ma, Gang Niu, Xianzhong Zhang, Xiaoyuan Chen, 2019
NIR-II emissive dye based polymer nanoparticle targeting EGFR for oral cancer theranostics, Mingjian Ling, Rui Sun, Guang Li, Madiha Zahra Syeda, Wen Ma, Ziyi Mai, Longquan Shao, Longguang Tang, Zhiqiang Yu, 2022
Long-term live-cell lipid droplet-targeted biosensor development for nanoscopic tracking of lipid droplet-mitochondria contact sites, Chengying Zhang, Huarong Shao, Xinyan Guo, Yue Liu, Jie Zhang, Zhigang Song, Fei Liu, Peixue Ling, Longguang Tang, KangNan Wang, Qixin Chen, 2021
Design, synthesis and structure-activity relationship study of novel indole-2-carboxamide derivatives as anti-inflammatory agents for the treatment of sepsis, Zhiguo Liu, Longguang Tang, Heping Zhu, Tingting Xu, Chenyu Qiu, Suqing Zheng, Yugui Gu, Jianpeng Feng, Yali Zhang, Guang Liang, 2016
Recent developments in mesoporous polydopamine-derived nanoplatforms for cancer theranostics, Zhu M, Shi Y, Shan Y, Guo J, Song X, Wu Y, Wu M, Lu Y, Chen W, Xu X, Tang L, 2021
Radiolabeled Angiogenesis-Targeting Croconaine Nanoparticles for Trimodality Imaging Guided Photothermal Therapy of Glioma, Longguang Tang, Xiaoli Sun, Nian Liu, Zijian Zhou, Fei Yu, Xianzhong Zhang, Xiaolian Sun, Xiaoyuan Chen, 2018
Redox-responsive dual chemophotothermal therapeutic nanomedicine for imaging-guided combinational therapy, Fei Yu, Fuwu Zhang, Longguang Tang, Jingwen Ma, Daishun Ling, Xiaoyuan Chen, Xiaolian Sun, 2018
Synthesis and biological evaluation of allylated and prenylated mono-carbonyl analogues of curcumin as anti-inflammatory agents, Zhiguo Liu, Longguang Tang, Peng Zou, Yali Zhang, Zhe Wang, Qilu Fang, Lili Jiang, Gaozhi Chen, Zheng Xu, Guang Liang, 2014

Drug Delivery Lysosome Protein Degradation Molecular Imaging Probes Cancer Stroke Nanomedicine Antibody-Drug Conjugates Small Molecule Drugs

H. Wang - Zhejiang University

Wei Chen - Zhejiang University

Yunhua Liu - Zhejiang University

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