Upload Avatar (500 x 500)
Longguang Tang
Medical School
Zhejiang University
Zhejiang
Language: English, Chinese
Drug Delivery
Lysosome
Protein Degradation
Molecular Imaging
Probes
Cancer
Stroke
Nanomedicine
Antibody-Drug Conjugates
Small Molecule Drugs
Areas of Focus
- Drug Delivery
- Lysosome-Targeted Protein Degradation
- Molecular Imaging Probes
Work Experience
- Researcher, Doctoral Supervisor - Zhejiang University
- Vice Editor - Nano TransMed
- Youth Editorial Board Member - Research, Asian Journal of Pharmaceutical Sciences, VIEW
Academic Background & Achievements
- PhD: Xiamen University - NIH Joint Program
- Postdoc: Stanford University
- Developed targeted small molecules and nano delivery systems for cancer and brain injury
- Published over 50 SCI papers, 30 as first/corresponding author
- 7 authorized national invention patents
Publications
- A DNA origami device spatially controls CD95 signalling to induce immune tolerance in rheumatoid arthritis, Ling Li, Jue Yin, Wen Ma, Longguang Tang, Jianhua Zou, Linzi Yang, Ting Du, Yi Zhao, Lianhui Wang, Zhen Yang, Chunhai Fan, Jie Chao, Xiaoyuan Chen, 2024
- Neutrophil Targeting Platform Reduces Neutrophil Extracellular Traps for Improved Traumatic Brain Injury and Stroke Theranostics, Mu Q, Yao K, Syeda MZ, Wan J, Cheng Q, You Z, Sun R, Zhang Y, Zhang H, Lu Y, Luo Z, Li Y, Liu F, Liu H, Zou X, Zhu Y, Peng K, Huang C, Chen X, Tang L, 2024
- Targeting Neutrophils for Enhanced Cancer Theranostics, Longguang Tang, Zhantong Wang, Qingchun Mu, Zhiqiang Yu, Orit Jacobson, Ling Li, Weijing Yang, Chunming Huang, Fei Kang, Wenpei Fan, Ying Ma, Maosheng Wang, Zijian Zhou, Xiaoyuan Chen, 2020
- Bioactivable Sting Nanoagonists to Synergize Nir-Ii Mild Photothermal Therapy Primed Robust and Long-Term Anticancer Immunity, Wen Ma, Rui Sun, Longguang Tang, Zibo Li, Ling Lin, Ziyi Mai, Gui Chen, Zhiqiang Yu, 2023
- Hesperetin nanoparticle targeting neutrophils for enhanced TBI therapy, Kai Yao, Qingchun Mu, Yufei Zhang, Qian Cheng, Xiaozhi Cheng, Xiaojing Liu, Chunmei Luo, Chumei Li, Shuxia Cai, Zhicheng Luo, Xiulong Zhu, Xiangtong Zhang, Liao Cui, Chunming Huang, Longguang Tang, 2022
- Ligustrazine Nanoparticle Hitchhiking On Neutrophils For Enhanced Therapy Of Cerebral Ischemia-Reperfusion Injury, Qingchun Mu, Kai Yao, Madiha Zahra Syeda, Min Zhang, Qian Cheng, Yufei Zhang, Rui Sun, Yuting Lu, Huamiao Zhang, Zhicheng Luo, Hanning Huang, Xiaojing Liu, Chunmei Luo, Xiulong Zhu, Shuyu Wu, Liao Cui, Chunming Huang, Xiaoyuan Chen, Longguang Tang, 2023
- Ferroptosis Detection: From Approaches to Applications, Fantian Zeng, Sureya Nijiati, Longguang Tang, Jinmin Ye, Zijian Zhou, Xiaoyuan Chen, 2023
- Coordinating the mechanism of actions of ferroptosis and photothermal effect for cancer theranostics, Fantian Zeng, Longguang Tang, Qianyu Zhang, Changrong Shi, Zicheng Huang, Sureya Nijiati, Xiaoyuan Chen, Zijian Zhou, 2021
- A Prodrug nanoplatform via esterification of STING agonist and IDO inhibitor for synergistic cancer immunotherapy, Madiha Zahra Syeda, Tu Hong, Min Zhang, Yanfei Han, Xiaoling Zhu, Songmin Ying, Longguang Tang, 2022
- LAT1 Targeted Brain Delivery of Temozolomide and Sorafenib for Effective Glioma Therapy, Yufei Zhang, Qian Cheng, Yuhao Xue, Kai Yao, Madiha Zahra Syeda, Jian Xu, Jianheng Wu, Zhenjie Wang, Longguang Tang, Qingchun Mu, 2023
- pH-activated nanoplatform for visualized photodynamic and ferroptosis synergistic therapy of tumors, Rui Sun, Wen Ma, Mingjian Ling, Chenhong Tang, Min Zhong, Jingyue Dai, Meiyan Zhu, Xuzi Cai, Guang Li, Qing Xu, Longguang Tang, Zhiqiang Yu, Zhenwei Peng, 2022
- Nanodevices for deep cartilage penetration, Xiao-Ling Xu, Yan Xue, Jia-Ying Ding, Zhi-Heng Zhu, Xi-Chen Wu, Yong-Jia Song, Yue-Long Cao, Long-Guang Tang, Dao-Fang Ding, Jian-Guang Xu, 2022
- Recent advances of bioresponsive polymeric nanomedicine for cancer therapy, Tu Hong, Xinyuan Shen, Madiha Zahra Syeda, Yang Zhang, Haonan Sheng, Yipeng Zhou, JinMing Xu, Chaojie Zhu, Hongjun Li, Zhen Gu, Longguang Tang, 2022
- Delivery of triptolide: a combination of traditional Chinese medicine and nanomedicine, Rui Sun, Jingyue Dai, Mingjian Ling, Ling Yu, Zhiqiang Yu, Longguang Tang, 2022
- Smart NIR-II croconaine dye-peptide for enhanced photo-sonotheranostics of hepatocellular carcinoma, Shuang Li, Yang Zhang, Xue Liu, Ye Tian, Yi Cheng, Longguang Tang, Huirong Lin, 2022
- Croconaine Nanoparticles with Enhanced Tumor Accumulation for Multimodality Cancer Theranostic, Longguang Tang, Fuwu Zhang, Fei Yu, Wenjing Sun, Menglin Song, Xiaoyuan Chen, Xianzhong Zhang, Xiaolian Sun, 2017
- A logic-gated modular nanovesicle enables programmable drug release for on-demand chemotherapy, Longguang Tang, Zhen Yang, Zijian Zhou, Ying Ma, Dale O. Kiesewetter, Zhantong Wang, Wenpei Fan, Shoujun Zhu, Mingru Zhang, Rui Tian, Lixin Lang, Gang Niu, Xianzhong Zhang, Xiaoyuan Chen, 2019
- Radioiodinated Small-Molecule Tyrosine Kinase Inhibitor for HER2-Selective SPECT Imaging, Longguang Tang, Chenyu Peng, Bowen Tang, Zijing Li, Xiangyu Wang, Jindian Li, Fei Gao, Lumei Huang, Duo Xu, Pu Zhang, Rongqiang Zhuang, Xinhui Su, Xiaoyuan Chen, Xianzhong Zhang, 2018
- Tumor Microenvironment-Activated Ratiometric Photoacoustic Nanoprobes for Specific Ultrasensitive Detection of Intratumoral Glutathione, Longguang Tang, Fei yu, Bowen Tang, Wenpei Fan, Mingru Zhang, Zhantong Wang, Zhen Yang, Orit Jacobson, Zijian Zhou, Ling Li, Yijing Liu, Dale O. Kiesewetter, Wei Tang, Liangcan He, Ying Ma, Gang Niu, Xianzhong Zhang, Xiaoyuan Chen, 2019
- NIR-II emissive dye based polymer nanoparticle targeting EGFR for oral cancer theranostics, Mingjian Ling, Rui Sun, Guang Li, Madiha Zahra Syeda, Wen Ma, Ziyi Mai, Longquan Shao, Longguang Tang, Zhiqiang Yu, 2022
- Long-term live-cell lipid droplet-targeted biosensor development for nanoscopic tracking of lipid droplet-mitochondria contact sites, Chengying Zhang, Huarong Shao, Xinyan Guo, Yue Liu, Jie Zhang, Zhigang Song, Fei Liu, Peixue Ling, Longguang Tang, KangNan Wang, Qixin Chen, 2021
- Design, synthesis and structure-activity relationship study of novel indole-2-carboxamide derivatives as anti-inflammatory agents for the treatment of sepsis, Zhiguo Liu, Longguang Tang, Heping Zhu, Tingting Xu, Chenyu Qiu, Suqing Zheng, Yugui Gu, Jianpeng Feng, Yali Zhang, Guang Liang, 2016
- Recent developments in mesoporous polydopamine-derived nanoplatforms for cancer theranostics, Zhu M, Shi Y, Shan Y, Guo J, Song X, Wu Y, Wu M, Lu Y, Chen W, Xu X, Tang L, 2021
- Radiolabeled Angiogenesis-Targeting Croconaine Nanoparticles for Trimodality Imaging Guided Photothermal Therapy of Glioma, Longguang Tang, Xiaoli Sun, Nian Liu, Zijian Zhou, Fei Yu, Xianzhong Zhang, Xiaolian Sun, Xiaoyuan Chen, 2018
- Redox-responsive dual chemophotothermal therapeutic nanomedicine for imaging-guided combinational therapy, Fei Yu, Fuwu Zhang, Longguang Tang, Jingwen Ma, Daishun Ling, Xiaoyuan Chen, Xiaolian Sun, 2018
- Synthesis and biological evaluation of allylated and prenylated mono-carbonyl analogues of curcumin as anti-inflammatory agents, Zhiguo Liu, Longguang Tang, Peng Zou, Yali Zhang, Zhe Wang, Qilu Fang, Lili Jiang, Gaozhi Chen, Zheng Xu, Guang Liang, 2014
Awards
- Alavi–Mandell Award: American Society of Nuclear Medicine and Molecular Imaging
