Areas of Focus
- Chromatin Structure and Transcription Regulation
- Epigenomic Modifications
- Circular DNA
Work Experience
- 2017-2021 - Jackson Laboratory for Genomic Medicine, USA - Postdoctoral Researcher
- 2022-Present - Zhejiang University - Researcher, Doctoral Supervisor
Academic Background & Achievements
- 2017-2021: Postdoctoral Research at Jackson Laboratory for Genomic Medicine, USA
- 2022: Joined Zhejiang University
- Participated in ENCODE and 4DN genome projects
- Published in Cancer Cell, Cell Stem Cell, Trends in Cancer
Publications
- Guilt-by-Association: EcDNA, a mobile trans-activator in cancer, Zhu Y., Gong L., Wei C. L., 2022
- Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription, Zhu Y., Gujar A.D., Wong C.H., Tjong H., Ngan C.Y., Gong L., Chen Y.A., Kim H., Liu J., Li M., Mil-Homens A., Maurya R., Kuhlberg C., Sun F., Yi E., deCarvalho A.C., Ruan Y., Verhaak R.G.W., Wei C.L., 2021
- Mapping the global chromatin connectivity network for Sox2 function in neural stem cell maintenance, Bertolini J. A., Favaro R., Zhu Y., Pagin M., Ngan C. Y., Wong C. H., Tjong H., Vermunt M. W., Martynoga B., Barone C., Mariani J., Cardozo M. J., Tabanera N., Zambelli F., Mercurio S., Ottolenghi S., Robson P., Creyghton M. P., Bovolenta P., Pavesi G., Guillemot F., Nicolis S. K., Wei C. L., 2019
- Processes underlying a reproductive barrier in indica-japonica rice hybrids revealed by transcriptome analysis, Zhu Y., Yu Y., Cheng K., Ouyang Y., Wang J., Gong L., Zhang Q., Li X., Xiao J., Zhang Q., 2017
- Sox2 controls neural stem cell self-renewal through a Fos-centered gene regulatory network, Pagin M., Pernebrink M., Giubbolini S., Barone C., Sambruni G., Zhu Y., Chiara M., Ottolenghi S., Pavesi G., Wei C.L., Cantù C., Nicolis S.K., 2021
- Sox2-dependent 3D chromatin interactomes in transcription, neural stem cell proliferation and neurodevelopmental diseases, Wei C.L., Nicolis S.K., Zhu Y., Pagin M., 2019
- The calcium‐dependent kinase OsCPK24 functions in cold stress responses in rice, Liu Y., Xu C., Zhu Y., Zhang L., Chen T., Zhou F., Chen H., Lin Y., 2018