Professor | Jichun Zhou | Asia Growth Partners

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Name	Jichun Zhou
Contact Information	jichun-zhou@zju.edu.cn
Language ability	English, Chinese
Province	Zhejiang

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Name

Jichun Zhou

Contact Information

jichun-zhou@zju.edu.cn

Language ability

English, Chinese

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	Yale University and Zhejiang University Joint PhD in Oncology Postdoctoral Research at Yale University Visiting Scholar at Addenbrooke's Hospital, Cambridge University Visiting Scholar at St. George's Hospital, University of London Key Teacher in the Teacher Training Program at the University of Western Australia
Work Experience	Zhejiang University School of Medicine, Associate Chief Physician in Oncology Surgery Zhejiang University School of Medicine, Associate Professor and Doctoral Supervisor
Awards	Zhejiang Provincial Outstanding Youth Science Fund Project Recipient Zhejiang Provincial High-Level Health Talent Training Object (Zhejiang Medical New Star) Zhejiang University Zheng Shu Medical Elite Scholarship Recipient Zhejiang University School of Medicine Affiliated Shao Yifu Hospital Excellent Young Talent Cultivation Project First China Clinical Oncology Society (CSCO) '35 under 35' Young Potential Oncologist Title

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

Yale University and Zhejiang University Joint PhD in Oncology
Postdoctoral Research at Yale University
Visiting Scholar at Addenbrooke's Hospital, Cambridge University
Visiting Scholar at St. George's Hospital, University of London
Key Teacher in the Teacher Training Program at the University of Western Australia

Work Experience

Zhejiang University School of Medicine, Associate Chief Physician in Oncology Surgery
Zhejiang University School of Medicine, Associate Professor and Doctoral Supervisor

Awards

Zhejiang Provincial Outstanding Youth Science Fund Project Recipient
Zhejiang Provincial High-Level Health Talent Training Object (Zhejiang Medical New Star)
Zhejiang University Zheng Shu Medical Elite Scholarship Recipient
Zhejiang University School of Medicine Affiliated Shao Yifu Hospital Excellent Young Talent Cultivation Project
First China Clinical Oncology Society (CSCO) '35 under 35' Young Potential Oncologist Title

Areas of Focus	Individualized comprehensive treatment of breast cancer surgery (whole process, holistic fine management) Mechanisms of breast cancer metastasis and drug resistance and reversal strategies Antitumor mechanisms of metformin Role of novel forms of cell death in tumorigenesis and development
Publications	Metformin induces Ferroptosis by inhibiting UFMylation of SLC7A11 in breast cancer, Yang J, Zhou Y, Xie S, Wang J, Li Z, Chen L, Mao M, Chen C, Huang A, Chen Y, Zhang X, Khan NUH, Wang L, Zhou J, 2021 The long noncoding RNA H19 promotes tamoxifen resistance in breast cancer via autophagy, Wang J, Xie S, Yang J, Xiong H, Jia Y, Zhou Y, Chen Y, Ying X, Chen C, Ye C, Wang L, Zhou J, 2019 PreImplantation factor promotes neuroprotection by targeting microRNA let-7, Mueller M, Zhou J, Yang L, Gao Y, Wu F, Schoeberlein A, Surbek D, Barnea ER, Paidas M, Huang Y, 2014 H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase, Zhou J, Yang L, Zhong T, Mueller M, Men Y, Zhang N, Xie J, Giang K, Chung H, Sun X, Lu L, Carmichael GG, Taylor HS, Huang Y, 2015 PLAC8 promotes adriamycin resistance via blocking autophagy in breast cancer, Chen Y, Jia Y, Mao M, Gu Y, Xu C, Yang J, Hu W, Shen J, Hu D, Chen C, Li Z, Chen L, Ruan J, Shen P, Zhou J, Wei Q, Wang L, 2021 Establishment and Characterization of a HER2-Positive Cell Line Derived From the Pleural Effusion of a Drug-Resistant Breast Cancer Patient, Li Z, Zhuo W, Chen L, Zhang X, Chen C, Hu D, Chen Y, Yang J, Zhou Y, Mao M, Xu L, Ju S, Shen J, Wang Q, Dong M, Xie S, Zhou J, Wang L, 2021 Polyphyllin Ⅲ-Induced Ferroptosis in MDA-MB-231 Triple-Negative Breast Cancer Cells can Be Protected Against by KLF4-Mediated Upregulation of xCT, Zhou Y, Yang J, Chen C, Li Z, Chen Y, Zhang X, Wang L, Zhou J, 2021 Regulation of tamoxifen sensitivity by the PLAC8/MAPK pathway axis is antagonized by curcumin-induced protein stability change, Mao M, Hu D, Yang J, Chen Y, Zhang X, Shen J, Teng R, Zhou J, Wang L, 2021 Targeting ferroptosis in breast cancer, Li Z, Chen L, Chen C, Zhou Y, Hu D, Yang J, Chen Y, Zhuo W, Mao M, Zhang X, Xu L, Wang L, Zhou J, 2020 The crosstalk between autophagy and ferroptosis: what can we learn to target drug resistance in cancer?, Zhou Y, Shen Y, Chen C, Sui X, Yang J, Wang L, Zhou J, 2019 Cancer-associated fibroblasts in breast cancer: Challenges and opportunities, Hu D, Li Z, Zheng B, Lin X, Pan Y, Gong P, Zhuo W, Hu Y, Chen C, Chen L, Zhou J, Wang L, 2022 Predictive and prognostic biomarkers of bone metastasis in breast cancer: current status and future directions, Wang S, Wu W, Lin X, Zhang KM, Wu Q, Luo M, Zhou J, 2023

Areas of Focus

Individualized comprehensive treatment of breast cancer surgery (whole process, holistic fine management)
Mechanisms of breast cancer metastasis and drug resistance and reversal strategies
Antitumor mechanisms of metformin
Role of novel forms of cell death in tumorigenesis and development

Publications

Metformin induces Ferroptosis by inhibiting UFMylation of SLC7A11 in breast cancer, Yang J, Zhou Y, Xie S, Wang J, Li Z, Chen L, Mao M, Chen C, Huang A, Chen Y, Zhang X, Khan NUH, Wang L, Zhou J, 2021
The long noncoding RNA H19 promotes tamoxifen resistance in breast cancer via autophagy, Wang J, Xie S, Yang J, Xiong H, Jia Y, Zhou Y, Chen Y, Ying X, Chen C, Ye C, Wang L, Zhou J, 2019
PreImplantation factor promotes neuroprotection by targeting microRNA let-7, Mueller M, Zhou J, Yang L, Gao Y, Wu F, Schoeberlein A, Surbek D, Barnea ER, Paidas M, Huang Y, 2014
H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase, Zhou J, Yang L, Zhong T, Mueller M, Men Y, Zhang N, Xie J, Giang K, Chung H, Sun X, Lu L, Carmichael GG, Taylor HS, Huang Y, 2015
PLAC8 promotes adriamycin resistance via blocking autophagy in breast cancer, Chen Y, Jia Y, Mao M, Gu Y, Xu C, Yang J, Hu W, Shen J, Hu D, Chen C, Li Z, Chen L, Ruan J, Shen P, Zhou J, Wei Q, Wang L, 2021
Establishment and Characterization of a HER2-Positive Cell Line Derived From the Pleural Effusion of a Drug-Resistant Breast Cancer Patient, Li Z, Zhuo W, Chen L, Zhang X, Chen C, Hu D, Chen Y, Yang J, Zhou Y, Mao M, Xu L, Ju S, Shen J, Wang Q, Dong M, Xie S, Zhou J, Wang L, 2021
Polyphyllin Ⅲ-Induced Ferroptosis in MDA-MB-231 Triple-Negative Breast Cancer Cells can Be Protected Against by KLF4-Mediated Upregulation of xCT, Zhou Y, Yang J, Chen C, Li Z, Chen Y, Zhang X, Wang L, Zhou J, 2021
Regulation of tamoxifen sensitivity by the PLAC8/MAPK pathway axis is antagonized by curcumin-induced protein stability change, Mao M, Hu D, Yang J, Chen Y, Zhang X, Shen J, Teng R, Zhou J, Wang L, 2021
Targeting ferroptosis in breast cancer, Li Z, Chen L, Chen C, Zhou Y, Hu D, Yang J, Chen Y, Zhuo W, Mao M, Zhang X, Xu L, Wang L, Zhou J, 2020
The crosstalk between autophagy and ferroptosis: what can we learn to target drug resistance in cancer?, Zhou Y, Shen Y, Chen C, Sui X, Yang J, Wang L, Zhou J, 2019
Cancer-associated fibroblasts in breast cancer: Challenges and opportunities, Hu D, Li Z, Zheng B, Lin X, Pan Y, Gong P, Zhuo W, Hu Y, Chen C, Chen L, Zhou J, Wang L, 2022
Predictive and prognostic biomarkers of bone metastasis in breast cancer: current status and future directions, Wang S, Wu W, Lin X, Zhang KM, Wu Q, Luo M, Zhou J, 2023

Breast Cancer Surgery Individualized Treatment Metastasis Drug Resistance Reversal Strategies Metformin Antitumor Cell Death Tumorigenesis

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