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Jichun Zhou
Medical School
Zhejiang University
Zhejiang
Language: English, Chinese
Breast Cancer
Surgery
Individualized Treatment
Metastasis
Drug Resistance
Reversal Strategies
Metformin
Antitumor
Cell Death
Tumorigenesis
Areas of Focus
- Individualized comprehensive treatment of breast cancer surgery (whole process, holistic fine management)
- Mechanisms of breast cancer metastasis and drug resistance and reversal strategies
- Antitumor mechanisms of metformin
- Role of novel forms of cell death in tumorigenesis and development
Work Experience
- Zhejiang University School of Medicine, Associate Chief Physician in Oncology Surgery
- Zhejiang University School of Medicine, Associate Professor and Doctoral Supervisor
Academic Background & Achievements
- Yale University and Zhejiang University Joint PhD in Oncology
- Postdoctoral Research at Yale University
- Visiting Scholar at Addenbrooke's Hospital, Cambridge University
- Visiting Scholar at St. George's Hospital, University of London
- Key Teacher in the Teacher Training Program at the University of Western Australia
Publications
- Metformin induces Ferroptosis by inhibiting UFMylation of SLC7A11 in breast cancer, Yang J, Zhou Y, Xie S, Wang J, Li Z, Chen L, Mao M, Chen C, Huang A, Chen Y, Zhang X, Khan NUH, Wang L, Zhou J, 2021
- The long noncoding RNA H19 promotes tamoxifen resistance in breast cancer via autophagy, Wang J, Xie S, Yang J, Xiong H, Jia Y, Zhou Y, Chen Y, Ying X, Chen C, Ye C, Wang L, Zhou J, 2019
- PreImplantation factor promotes neuroprotection by targeting microRNA let-7, Mueller M, Zhou J, Yang L, Gao Y, Wu F, Schoeberlein A, Surbek D, Barnea ER, Paidas M, Huang Y, 2014
- H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase, Zhou J, Yang L, Zhong T, Mueller M, Men Y, Zhang N, Xie J, Giang K, Chung H, Sun X, Lu L, Carmichael GG, Taylor HS, Huang Y, 2015
- PLAC8 promotes adriamycin resistance via blocking autophagy in breast cancer, Chen Y, Jia Y, Mao M, Gu Y, Xu C, Yang J, Hu W, Shen J, Hu D, Chen C, Li Z, Chen L, Ruan J, Shen P, Zhou J, Wei Q, Wang L, 2021
- Establishment and Characterization of a HER2-Positive Cell Line Derived From the Pleural Effusion of a Drug-Resistant Breast Cancer Patient, Li Z, Zhuo W, Chen L, Zhang X, Chen C, Hu D, Chen Y, Yang J, Zhou Y, Mao M, Xu L, Ju S, Shen J, Wang Q, Dong M, Xie S, Zhou J, Wang L, 2021
- Polyphyllin Ⅲ-Induced Ferroptosis in MDA-MB-231 Triple-Negative Breast Cancer Cells can Be Protected Against by KLF4-Mediated Upregulation of xCT, Zhou Y, Yang J, Chen C, Li Z, Chen Y, Zhang X, Wang L, Zhou J, 2021
- Regulation of tamoxifen sensitivity by the PLAC8/MAPK pathway axis is antagonized by curcumin-induced protein stability change, Mao M, Hu D, Yang J, Chen Y, Zhang X, Shen J, Teng R, Zhou J, Wang L, 2021
- Targeting ferroptosis in breast cancer, Li Z, Chen L, Chen C, Zhou Y, Hu D, Yang J, Chen Y, Zhuo W, Mao M, Zhang X, Xu L, Wang L, Zhou J, 2020
- The crosstalk between autophagy and ferroptosis: what can we learn to target drug resistance in cancer?, Zhou Y, Shen Y, Chen C, Sui X, Yang J, Wang L, Zhou J, 2019
- Cancer-associated fibroblasts in breast cancer: Challenges and opportunities, Hu D, Li Z, Zheng B, Lin X, Pan Y, Gong P, Zhuo W, Hu Y, Chen C, Chen L, Zhou J, Wang L, 2022
- Predictive and prognostic biomarkers of bone metastasis in breast cancer: current status and future directions, Wang S, Wu W, Lin X, Zhang KM, Wu Q, Luo M, Zhou J, 2023
Awards
- Zhejiang Provincial Outstanding Youth Science Fund Project Recipient
- Zhejiang Provincial High-Level Health Talent Training Object (Zhejiang Medical New Star)
- Zhejiang University Zheng Shu Medical Elite Scholarship Recipient
- Zhejiang University School of Medicine Affiliated Shao Yifu Hospital Excellent Young Talent Cultivation Project
- First China Clinical Oncology Society (CSCO) '35 under 35' Young Potential Oncologist Title
