2021.01 - Present: Zhejiang University School of Medicine, Associate Researcher
2016.01 - 2020.12: Sun Yat-sen University/Guangzhou Medical University, Associate PI
2011.08 - 2015.12: Roswell Park Cancer Institute, Postdoctoral Researcher
2007.09 - 2008.09: Kiel University, Joint PhD Student
2006.09 - 2011.06: Zhejiang University, PhD in Animal Genetics, Breeding and Reproduction
2002.10 - 2006.06: Zhejiang University, Bachelor's in Veterinary Medicine
2021.01 - Present: Zhejiang University School of Medicine, Associate Researcher
2016.01 - 2020.12: Sun Yat-sen University/Guangzhou Medical University, Associate PI
2011.08 - 2015.12: Roswell Park Cancer Institute, Postdoctoral Researcher
Research
Genetic disease modeling, mechanisms, and treatment research
Mechanisms underlying the efficacy and limitation of dopa and tetrahydrobiopterin therapies for the deficiency of GTP cyclohydrolase 1 revealed in a novel mouse model, Xiaoling Jiang, Yongxian Shao, Yongqiang Liao, Xiaoning Zheng, Minzhi Peng, Yanna Cai, Meiyi Wang, Huazhen Liu, Chunhua Zeng, Yunting Lin, Wen Zhang, Li Liu, 2024
Establishment and characterization of ZJUCHi003: an induced pluripotent stem cell line from a patient with Temple–Baraitser/Zimmermann–Laband syndrome carrying KCNH1 c.1070G > A (p.R357Q) variant, Die Chen, Jimei Su, Xueying Huang, Hongyu Chen, Tiejia Jiang, Chunchun Zhi, Zuolin Zhou, Lan Yu, Xiaoling Jiang, 2024
Single-nucleus RNA sequencing reveals cell type-specific transcriptome alterations of Down syndrome hippocampus using the Dp16 mouse model, Zuolin Zhou, Chunchun Zhi, Die Chen, Zhaowei Cai, Xiaoling Jiang, 2023
Dissection of a Down syndrome-associated trisomy to separate the gene dosage-dependent and -independent effects of an extra chromosome, Xing Z, Li Y, Cortes-Gomez E, Jiang X, Gao S, Pao A, Shan J, Song Y, Perez A, Yu T, Highsmith M, Boadu F, Conroy J, Singh P, Bakin A, Cheng J, Duan Z, Wang J, Liu S, Tycko B, Yu YE, 2023
Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism, Peng M, Shao Y, Li X, Zhang K, Cai Y, Lin Y, Jiang M, Liu Z, Su X, Zhang W, Jiang X, Liu L, 2022
FMR1 allele frequencies in 51,000 newborns: a large-scale population study in China, Zhang J, Wu D, Yang R, Zhu L, Jiang M, Wang W, Li X, Jiang X, Tong F, Shu Q, 2021
A GM1 gangliosidosis mutant mouse model exhibits activated microglia and disturbed autophagy, Liu S, Feng Y, Huang Y, Jiang X, Tang C, Tang F, Zeng C, Liu L, 2021
Comparative analysis of the Down syndrome hippocampal non-coding RNA transcriptomes using a mouse model, Cai Z, Xiao Z, Wang Y, Liu H, Zhang K, Zhen X, Jiang X, 2020
Distinct severity of phenotype in Hajdu-Cheney syndrome: a case report and literature review, Zeng C, Lin Y, Lu Z, Chen Z, Jiang X, Mao X, Liu Z, Lu X, Zhang K, Yu Q, Wang X, Huang Y, Liu L, 2020
HOXA9 rs3801776 G>A polymorphism increases congenital talipes equinovarus risk in a Chinese population, Li J, Wu J, Liu Y, Li Y, Xiao Z, Jiang X, Tang Y, Xu H, 2019
A novel GTPCH deficiency mouse model exhibiting tetrahydrobiopterin related metabolic disturbance and infancy-onset motor impairments, Jiang X, Liu H, Shao Y, Peng M, Zhang W, Li D, Li X, Cai Y, Tan T, Lu X, Xu J, Su X, Lin Y, Liu Z, Huang Y, Zeng C, Tang Y, Liu L, 2019
Analysis of mutations in primary and metastatic synovial sarcoma, Xing Z, Wei L, Jiang X, Conroy J, Glenn S, Bshara W, Yu T, Pao A, Tanaka S, Kawai A, Choi C, Wang J, Liu S, Morrison C, Yu YE, 2018
Triplications of human chromosome 21 orthologous regions in mice result in expansion of megakaryocyte-erythroid progenitors and reduction of granulocyte-macrophage progenitors, Liu C, Yu T, Xing Z, Jiang X, Li Y, Pao A, Mu J, Wallace PK, Stoica G, Bakin AV, Yu YE, 2017
Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models, Mendioroz M, Do C, Jiang X, Liu C, Darbary HK, Lang CF, Lin J, Thomas A, Abu-Amero S, Stainer P, Temkin A, Yale A, Liu M, Li Y, Salas M, Kerkel K, Capone G, Silverman W, Yu YE, Moore G, Wegiel J, Tycko B, 2015
Genetic dissection of the Down syndrome Critical Region, Jiang X, Liu C, Yu T, Zhang L, Meng K, Xing Z, Belichenko PV, Pao A, Peresie J, Wie S, Mobley WC, Yu YE, 2015
Transcriptomic analysis of hepatic responses to testosterone deficiency in miniature pigs fed a high-cholesterol diet, Cai Z, Jiang X, Pan Y, Chen L, Zhang L, Zhu K, Cai Y, Ling Y, Chen F, Xu X, Chen M, 2015
Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites, Grandi FC, Rosser JM, Newkirk SJ, Yin J, Jiang X, Xing Z, Whitmore L, Bashir S, Ivics Z, Izsvak Z, Ye P, Yu YE, An W, 2015
Effect of testosterone deficiency on cholesterol metabolism in pigs fed a high-fat and high-cholesterol diet, Cai Z, Xi H, Pan Y, Jiang X, Chen L, Cai Y, Zhu K, Chen C, Xu X, Chen M, 2015
Differential miRNA expression profiles in the longissimus dorsi muscle between intact and castrated male pigs, Cai Z, Zhang L, Jiang X, Sheng Y, Xu N, 2015
Engineered chromosome-based genetic mapping establishes a 3.7-Mb critical genomic region for Down syndrome-associated heart defects in mice, Liu C, Morishima M, Jiang X, Yu T, Meng K, Ray D, Pao A, Ye P, Parmacek MS, Yu YE, 2014
Human chromosome 21 orthologous region on mouse chromosome 17 is a major determinant of Down syndrome-related developmental cognitive deficits, Zhang L, Meng K, Jiang X, Liu C, Pao A, Belichenko PV, Kleschevnikov AM, Josselyn S, Liang P, Ye P, Mobley WC, Yu YE, 2014
Castration-induced changes in microRNA expression profiles in subcutaneous adipose tissue of male pigs, Cai Z, Zhang L, Chen M, Jiang X, Xu N, 2014
MicroRNA expression profiling of the porcine developing hypothalamus and pituitary tissue, Zhang L, Jiang X, Hua X, Lu Y, Xu N, 2013
Polymorphisms in porcine TRH and TRHR gene and associations with growth and fatness traits, Jiang X, Wang Y, Chen Z, Cai Z, Zhang L, Zhou H, Xu N, 2012
Molecular characterization of Hypothalamo-Pituitary-Thyroid genes in pig (Sus Scrofa), Xu N, Jiang X, 2012
Mapping, cDNA Cloning and tissue expression of the porcine thyrotropin-releasing hormone receptor gene, Jiang X, Cai Z, Zhao X, Zhang L, Chen Z, Wang Y, Guo X, Xu N, 2011
Polymorphisms of porcine CGA gene and its association analysis with growth and carcass traits, Jiang X, Zhang L, Xu N, Zhai J, Lv Z, 2011
Association of PPARγ2 polymorphisms with carcass and meat quality traits in a Pietrain ´ Jinhua F2 population, Chen Z, Zhao X, Jiang X, Guo X, Lv Z, Zhou H, Xu N, 2011
Molecular Characteristics of porcine SIM1 gene and its variants associations with carcass and meat quality traits, Chen Z, Zhao X, Hao Z, Jiang X, Guo X, Xu N, 2011
Mapping, expression and regulation of the TRα gene in porcine adipose tisue, Cai Z, Sheng Y, Zhang L, Wang Y, Jiang X, Lv Z, Xu N, 2011
Association of porcine UCP3 gene polymorphisms with fatness traits in a Pietrain × Jinhua F2 population, Chen Z, Zhao X, Hao Z, Guo X, Jiang X, Xu N, 2011
Molecular cloning, expression and polymorphism of the porcine apolipoprotein A5 gene in a Jinhua ´ Pietrain F-2 reference population, Zhang L, Jiang X, Hua X, Lu Y, Xu N, 2010
Area of Focus
Genetics | Population | Complex Diseases | Health Data | Computational Biology | Human Genome | Biomedical | Research | Genomics | Bioinformatics
