Professor | Zhexu Chi | Asia Growth Partners

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Name

Zhexu Chi

Contact Information

ralf@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	2012 - Bachelor's Degree: South China Normal University, School of Life Sciences 2020 - PhD in Immunology: Zhejiang University, School of Medicine 2020 - Postdoctoral Research: Zhejiang University, Institute of Immunology (Co-supervisor: Professor Wang Di) Published 3 papers as the first author in Molecular Cell (2020) and Immunity (2016, 2018) Over 600 citations on Google Scholar Research results recommended by F1000 members
Work Experience	2020-2022 - Zhejiang University, Institute of Immunology - Postdoctoral Researcher 2022-Present - Zhejiang University School of Medicine, Fourth Affiliated Hospital - Researcher

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

2012 - Bachelor's Degree: South China Normal University, School of Life Sciences
2020 - PhD in Immunology: Zhejiang University, School of Medicine
2020 - Postdoctoral Research: Zhejiang University, Institute of Immunology (Co-supervisor: Professor Wang Di)
Published 3 papers as the first author in Molecular Cell (2020) and Immunity (2016, 2018)
Over 600 citations on Google Scholar
Research results recommended by F1000 members

Work Experience

2020-2022 - Zhejiang University, Institute of Immunology - Postdoctoral Researcher
2022-Present - Zhejiang University School of Medicine, Fourth Affiliated Hospital - Researcher

Areas of Focus	Immunometabolism Pyroptosis Tissue Repair
Publications	Histone Deacetylase 3 Couples Mitochondria to Drive IL-1β-Dependent Inflammation by Configuring Fatty Acid Oxidation, Chi, Zhexu; Chen, Sheng; Xu, Ting; Zhen, Wenxuan; Yu, Weiwei; Jiang, Danlu; Guo, Xingchen; Wang, Zhen; Zhang, Kailian; Li, Mobai, 2020 Cholesterol homeostatic regulator SCAP-SREBP2 integrates NLRP3 inflammasome activation and cholesterol biosynthetic signaling in macrophages, Guo, Chuansheng; Chi, Zhexu; Jiang, Danlu; Xu, Ting; Yu, Weiwei; Wang, Zhen; Chen, Sheng; Zhang, Li; Liu, Qianyun; Guo, Xingchen, 2018 Bile acids control inflammation and metabolic disorder through inhibition of NLRP3 inflammasome, Guo, Chuansheng; Xie, Shujun; Chi, Zhexu; Zhang, Jinhua; Liu, Yangyang; Zhang, Li; Zheng, Mingzhu; Zhang, Xue; Xia, Dajing; Ke, Yuehai, 2016 One-carbon metabolism supports S-adenosylmethionine and histone methylation to drive inflammatory macrophages, Yu, Weiwei; Wang, Zhen; Zhang, Kailian; Chi, Zhexu; Xu, Ting; Jiang, Danlu; Chen, Sheng; Li, Wenxin; Yang, Xuyan; Zhang, Xue, 2019 Priming of NLRP3 inflammasome activation by Msn kinase MINK1 in macrophages, Kaixiang Zhu, Xuexiao Jin, Zhexu Chi, Sheng Chen, Songquan Wu, Richard D. Sloan, Xuai Lin, Dante Neculai, Di Wang, Hu Hu & Linrong Lu, 2021

Areas of Focus

Immunometabolism
Pyroptosis
Tissue Repair

Publications

Histone Deacetylase 3 Couples Mitochondria to Drive IL-1β-Dependent Inflammation by Configuring Fatty Acid Oxidation, Chi, Zhexu; Chen, Sheng; Xu, Ting; Zhen, Wenxuan; Yu, Weiwei; Jiang, Danlu; Guo, Xingchen; Wang, Zhen; Zhang, Kailian; Li, Mobai, 2020
Cholesterol homeostatic regulator SCAP-SREBP2 integrates NLRP3 inflammasome activation and cholesterol biosynthetic signaling in macrophages, Guo, Chuansheng; Chi, Zhexu; Jiang, Danlu; Xu, Ting; Yu, Weiwei; Wang, Zhen; Chen, Sheng; Zhang, Li; Liu, Qianyun; Guo, Xingchen, 2018
Bile acids control inflammation and metabolic disorder through inhibition of NLRP3 inflammasome, Guo, Chuansheng; Xie, Shujun; Chi, Zhexu; Zhang, Jinhua; Liu, Yangyang; Zhang, Li; Zheng, Mingzhu; Zhang, Xue; Xia, Dajing; Ke, Yuehai, 2016
One-carbon metabolism supports S-adenosylmethionine and histone methylation to drive inflammatory macrophages, Yu, Weiwei; Wang, Zhen; Zhang, Kailian; Chi, Zhexu; Xu, Ting; Jiang, Danlu; Chen, Sheng; Li, Wenxin; Yang, Xuyan; Zhang, Xue, 2019
Priming of NLRP3 inflammasome activation by Msn kinase MINK1 in macrophages, Kaixiang Zhu, Xuexiao Jin, Zhexu Chi, Sheng Chen, Songquan Wu, Richard D. Sloan, Xuai Lin, Dante Neculai, Di Wang, Hu Hu & Linrong Lu, 2021

Immunometabolism Metabolic Pathways Immune Response Inflammation Macrophages Cytokines Cell Death Pyroptosis Tissue Regeneration Molecular Mechanisms

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