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Zhongli Yang
zy3p@zju.edu.cn
English, Chinese
Zhejiang
Zhejiang University
Medical
  • 2011.4-2013.6: Exchange Student, Department of Psychiatric and Neurobehavioral Sciences, University of Virginia
  • 2009.9-2011.4: Ph.D., Department of Clinical Veterinary Medicine, Shanxi Agricultural University
  • 2006.9-2009.6: Master's, School of Food Science and Engineering, Wuhan Polytechnic University
  • 2001.9-2005.6: Bachelor's, School of Food Science and Engineering, Wuhan Polytechnic University
  • 2014.11-present: Assistant Researcher, The First Affiliated Hospital, Zhejiang University School of Medicine
  • 2013.6-2014.11: Postdoctoral Fellow, Institute of Neuroimmune Pharmacology, Seton Hall University, Supervisor: Sulie L. Chang
  • 2014: National Hispanic Science Network Young Investigator Travel Award
  • 2015: International Conference on Global Health Young Investigator Travel Award
  • 2020: The 26th Annual Meeting of Society For Research on Nicotine and Tobacco Travel Award
  • 2020: Top 10 in the 4th World Life Science and Technology Conference SATOL Innovation and Entrepreneurship Competition
  • 2020: Advanced Worker of Zhejiang University School of Medicine
Genomics and pharmacogenomics of nicotine dependence and depression
Functional genomics of nicotine dependence and depression
Bioinformatics
Human genetic epidemiology
Artificial intelligence predictive models for the diagnosis and treatment of depression
  • CAR-T cell therapy-related cytokine release syndrome and therapeutic response is modulated by the gut microbiome in hematologic malignancies, Hu Y, Li J, Ni F, Yang Z, Gui X, Bao Z, Zhao H, Wei G, Wang Y, Zhang M, Hong R, Wang L, Wu W, Mohty M, Nagler A, Chang AH, van den Brink MRM, Li MD, Huang H, 2022
  • Landscapes of gut microbiome and bile acids signatures and their interaction in HBV-associated acute on chronic liver failure, Bao Z, Wei R, Zheng X, Zhang T, Bi Y, Shen S, Zou P, Zhang J, Yan H, Li MD, Yang Z, Gao H, 2022
  • Investigation of the genetic effect of 56 tobacco-smoking susceptibility genes on DNA methylation and RNA expression in human brain, Yang Z, Yang J, Mao Y, Li MD, 2022
  • Identification of a Novel Functional Non-synonymous Single Nucleotide Polymorphism in Frizzled Class Receptor 6 Gene for Involvement in Depressive Symptoms, Han H, Xu M, Wen L, Chen J, Liu Q, Wang J, Li MD, Yang Z, 2022
  • Genome-wide methylation and expression analyses reveal the epigenetic landscape of immune-related diseases underlying tobacco smoking, Mao Y, Huang P, Wang M, Li MD, Yang Z, 2021
  • Integrative Analysis of epigenome and transcriptome data reveals aberrantly methylated promoters and enhancers in hepatocellular carcinoma, Huang P, Xu M, Han H, Zhao X, Li MD, Yang Z, 2021
  • Prediction of repeated-dose intravenous ketamine response in major depressive disorder using the GWAS-based machine learning approach, Bao Z, Zhao X, Li J, Zhang G, Wu H, Ning Y, Li MD, Yang Z, 2021
  • Identification of diagnostic markers for major depressive disorder using machine learning methods, Zhao S, Bao Z, Zhao X, Xu M, Li MD, Yang Z, 2021
  • Landscape analysis of lncRNAs shows that DDX11-AS1 promotes cell-cycle progression in liver cancer through the PARP1/p53 axis, Xu M, Zhao X, Zhao S, Yang Z, Yuan W, Han H, Zhang B, Zhou L, Zheng S, Li MD, 2021
  • Correlation between prognostic biomarker SLC1A5 and immune infiltrates in various types of cancers including hepatocellular carcinoma, Zhao J, Yang Z, Tu M, Meng W, Gao H, Li MD, Li L, 2021
  • Effect of Cigarette Smoke on Gut Microbiota: State of Knowledge, Gui X, Yang Z, Li MD, 2021
  • Clostridiales are predominant microbes that mediate psychiatric disorders, Li J, Ma Y, Bao Z, Gui X, Li AN, Yang Z, Li MD, 2020
  • Updated review of research on the gut microbiota and their relation to depression in animals and human beings, Yang Z, Li J, Gui X, Shi X, Bao Z, Han H, Li MD, 2020
  • Genome-wide DNA methylation analysis reveals significant impact of long-term ambient air pollution exposure on biological functions related to mitochondria and immune response, Wang M, Zhao J, Wang Y, Mao Y, Zhao X, Huang P, Liu Q, Ma Y, Yao Y, Yang Z, Yuan W, Cui W, Payne TJ, Li MD, 2020
  • Identification of 34 genes conferring genetic and pharmacological risk for the comorbidity of schizophrenia and smoking behaviors, Ma Y, Li J, Xu Y, Wang Y, Yao Y, Liu Q, Wang M, Zhao X, Fan R, Chen J, Zhang B, Cai Z, Han H, Yang Z, Yuan W, Zhong Y, Chen X, Ma JZ, Payne TJ, Xu Y, Ning Y, Cui W, Li MD, 2020
  • Gene-based association analysis reveals involvement of LAMA5 and cell adhesion pathways in nicotine dependence in African-and European-American samples, Fan R, Cui W, Chen J, Ma Y, Yang Z, Payne TJ, Ma JZ, Li MD, 2020
  • Demonstration of critical role of GRIN3A in nicotine dependence through both genetic association and molecular functional studies, Chen J, Liu Q, Fan R, Han H, Yang Z, Cui W, Song G, Li MD, 2020
  • Genetic and epigenetic analysis revealing variants in the NCAM1-TTC12-ANKK1-DRD2 cluster associated significantly with nicotine dependence in Chinese Han smokers, Liu Q, Xu Y, Mao Y, Ma Y, Wang M, Han H, Cui W, Yuan W, Payne TJ, Xu Y, Li MD, Yang Z, 2020
  • An Exome-Wide association study identifies new susceptibility loci for age of smoking initiation in African-and European-American populations, Jiang K, Yang Z, Cui W, Su K, Ma JZ, Payne TJ, Li MD, 2019
  • Involvement of interferon regulatory factor 7 in nicotine's suppression of antiviral immune responses, Han H, Huang W, Du W, Shen Q, Yang Z, Li MD, Chang SL, 2019
  • Association and cis-mQTL analysis of variants in CHRNA3-A5, CHRNA7, CHRNB2, and CHRNB4 in relation to nicotine dependence in a Chinese Han population, Liu Q, Han H, Wang M, Yao Y, Wen L, Jiang K, Ma Y, Fan R, Chen J, Su K, Yang Z, Cui W, Yuan W, Jiang X, Li J, Payne TJ, Wang J, Li MD, 2018
  • Pharmacological effects and regulatory mechanisms of tobacco smoking effects on food intake and weight control, Hu T, Yang Z, Li MD, 2018
  • Modulatory effects of nicotine on neuroHIV/neuroAIDS, Han H, Yang Z, Chang SL, Li MD, 2018
  • Association and cis-mQTL analysis of variants in serotonergic genes associated with nicotine dependence in Chinese Han smokers, Han H, Liu Q, Yang Z, Wang M, Ma Y, Cao L, Cui W, Yuan W, Payne TJ, Li L, Li MD, 2018
  • Implication of genes for the N-Methyl-D-Aspartate (NMDA) receptor in substance addictions, Chen J, Ma Y, Fan R, Yang Z, Li MD, 2018
  • HIV-1 proteins influence novelty-seeking behavior and alter region-specific transcriptional responses to chronic nicotine treatment in HIV-1Tg rats, Yang Z, Nesil T, Wingo T, Chang SL, Li MD, 2017
  • Modulation effect of HIV-1 viral proteins and nicotine on expression of the immune-related genes in brain of the HIV-1 transgenic rats, Yang Z, Nesil T, Connaghan KP, Li MD, Chang SL, 2016
  • Nicotine mediates expression of genes related to antioxidant capacity and oxidative stress response in HIV-1 transgenic rat brain, Song G, Nesil T, Cao J, Yang Z, Chang SL, Li MD, 2016
  • Involvement of the hippocampus in binge ethanol-induced spleen atrophy in adolescent rats, Liu X, Connaghan KP, Wei Y, Yang Z, Li MD, Chang SL, 2016
  • Nicotine attenuates the effect of HIV-1 proteins on the neural circuits of working and contextual memories, Nesil T, Cao J, Yang Z, Chang SL, Li MD, 2015
  • The contribution of rare and common variants in 30 genes to risk nicotine dependence, Yang J, Wang S, Yang Z, Hodgkinson CA, Iarikova P, Ma JZ, Payne TJ, Goldman D, Li MD, 2015
  • Introduction to deep sequencing and its application to drug addiction research with a focus on rare variants, Wang S, Yang Z, Ma JZ, Payne TJ, Li MD, 2014
Genomics Pharmacogenomics Nicotine Dependence Depression Functional Genomics Bioinformatics Genetic Epidemiology Artificial Intelligence Predictive Models Diagnosis

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