Professor | Xin Li | Asia Growth Partners

Name	Xin Li
Contact Information	xinli2021@cau.edu.cn
Language ability	Chinese, English
Province	Beijing

Name

Xin Li

Contact Information

xinli2021@cau.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	China Agricultural University
Faculty	Vetrinary Medicine
Academic Background & Achievements	2001-2006 Bachelor in Animal Medicine, Northeast Agricultural University 2006-2009 Master in Preventive Veterinary Medicine, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences 2009-2012 PhD in Preventive Veterinary Medicine, China Agricultural University National Youth Talent Project Winner Outstanding Talent introduced by China Agricultural University Independent PI of Infection and Immunity Research Platform
Work Experience	2012-2014 Postdoctoral Researcher, Department of Biochemistry and Biophysics, Texas A&M University, Supervisor: Professor Pingwei Li 2014-2020 Postdoctoral Researcher/Research Associate, Lineberger Cancer Center, University of North Carolina at Chapel Hill, Supervisor: Jenny P.-Y. Ting 2021-Present Professor, China Agricultural University
Awards	2021 National Natural Science Foundation Talent Project 2019 Keystone Symposium 'Innate Immune Receptors: Roles in Immunology and Beyond' Conference Grant 2011 'International Research on Epidemiology of Zoonoses and Training for Young Researchers' Conference Grant in Japan 2011 Best Academic Award at the National Veterinary Doctoral Forum China Agricultural University Research Achievement Award China Agricultural University Outstanding Graduate

University/Lab Affiliation and Title

China Agricultural University

Faculty

Vetrinary Medicine

Academic Background & Achievements

2001-2006 Bachelor in Animal Medicine, Northeast Agricultural University
2006-2009 Master in Preventive Veterinary Medicine, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences
2009-2012 PhD in Preventive Veterinary Medicine, China Agricultural University
National Youth Talent Project Winner
Outstanding Talent introduced by China Agricultural University
Independent PI of Infection and Immunity Research Platform

Work Experience

2012-2014 Postdoctoral Researcher, Department of Biochemistry and Biophysics, Texas A&M University, Supervisor: Professor Pingwei Li
2014-2020 Postdoctoral Researcher/Research Associate, Lineberger Cancer Center, University of North Carolina at Chapel Hill, Supervisor: Jenny P.-Y. Ting
2021-Present Professor, China Agricultural University

Awards

2021 National Natural Science Foundation Talent Project
2019 Keystone Symposium 'Innate Immune Receptors: Roles in Immunology and Beyond' Conference Grant
2011 'International Research on Epidemiology of Zoonoses and Training for Young Researchers' Conference Grant in Japan
2011 Best Academic Award at the National Veterinary Doctoral Forum
China Agricultural University Research Achievement Award
China Agricultural University Outstanding Graduate

Areas of Focus	Natural immune pattern recognition receptor Immune regulation of viral infection Molecular mechanism of virus escape from natural immune recognition cGAS-STING and NOD-like receptor signaling pathway
Publications	Species-specific cleavage of cGAS by picornavirus protease 3C disrupts mitochondria DNA-mediated immune sensing, Yan Y, Wu L, Yuan Y, Wang H, Yin H, Li M, Chai L, Liang R, Liu Y, Zhao D, Xing J, Li P, Li X, 2023 Impact of intracellular innate immune receptors on immunometabolism, Chou WC, Rampanelli E, Li X, Ting JP, 2021 Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon, Li X, Deng M, Petrucelli AS, Zhu C, Mo J, Zhang L, Tam JW, Ariel P, Zhao B, Zhang S, Ke H, Li P, Dokholyan NV, Duncan JA, Ting JP, 2019 Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization, Li X, Shu C, Yi G, Chaton CT, Shelton CL, Diao J, Zuo X, Kao CC, Herr AB, Li P, 2013 Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides, Li X, Liu J, Qi J, Gao F, Li Q, Li X, Zhang N, Xia C, Gao GF, 2011 The mechanism of double-stranded DNA sensing through the cGAS-STING pathway, Shu C, Li X, Li P, 2014 Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites, Guo H, Chou WC, Lai Y, Liang K, Tam JW, Brickey WJ, Chen L, Montgomery ND, Li X, Bohannon LM, Sung AD, Chao NJ, Peled JU, Gomes ALC, van den Brink MRM, French MJ, Macintyre AN, Sempowski GD, Tan X, Sartor RB, Lu K, Ting JP, 2020

Areas of Focus

Natural immune pattern recognition receptor
Immune regulation of viral infection
Molecular mechanism of virus escape from natural immune recognition
cGAS-STING and NOD-like receptor signaling pathway

Publications

Species-specific cleavage of cGAS by picornavirus protease 3C disrupts mitochondria DNA-mediated immune sensing, Yan Y, Wu L, Yuan Y, Wang H, Yin H, Li M, Chai L, Liang R, Liu Y, Zhao D, Xing J, Li P, Li X, 2023
Impact of intracellular innate immune receptors on immunometabolism, Chou WC, Rampanelli E, Li X, Ting JP, 2021
Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon, Li X, Deng M, Petrucelli AS, Zhu C, Mo J, Zhang L, Tam JW, Ariel P, Zhao B, Zhang S, Ke H, Li P, Dokholyan NV, Duncan JA, Ting JP, 2019
Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization, Li X, Shu C, Yi G, Chaton CT, Shelton CL, Diao J, Zuo X, Kao CC, Herr AB, Li P, 2013
Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides, Li X, Liu J, Qi J, Gao F, Li Q, Li X, Zhang N, Xia C, Gao GF, 2011
The mechanism of double-stranded DNA sensing through the cGAS-STING pathway, Shu C, Li X, Li P, 2014
Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites, Guo H, Chou WC, Lai Y, Liang K, Tam JW, Brickey WJ, Chen L, Montgomery ND, Li X, Bohannon LM, Sung AD, Chao NJ, Peled JU, Gomes ALC, van den Brink MRM, French MJ, Macintyre AN, Sempowski GD, Tan X, Sartor RB, Lu K, Ting JP, 2020

Immune Pattern Recognition Receptor Viral Infection Immune Regulation Molecular Mechanism Virus Escape Natural Immune Recognition Cgas-Sting Nod-Like Receptor Signaling Pathway Virus-Host Interaction

Zhangqi Shen - China Agricultural University

Xiaojia Wang - China Agricultural University

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