Upload Avatar (500 x 500)
Xin Li
Veterinary Medicine
China Agricultural University
Beijing
Language: English, Chinese
Infection
Immunity
Viral Infections
Natural Immune
Pattern Recognition Receptors
Cgas-Sting
Nod-Like Receptors
Immune Regulation
Molecular Mechanisms
Viral Escape
Areas of Focus
- Infection and immunity research focusing on natural immune pattern recognition receptors against viral infections
- Molecular mechanisms of viral escape from natural immune recognition
Work Experience
- 2012-2014 - Texas A&M University, Department of Biochemistry and Biophysics, Postdoctoral Researcher
- 2014-2020 - University of North Carolina at Chapel Hill, Lineberger Cancer Center, Postdoctoral Researcher/Research Associate
- 2021-Present - China Agricultural University, College of Veterinary Medicine, Professor
Academic Background & Achievements
- 2001-2006 Bachelor: Northeast Agricultural University, Veterinary Medicine
- 2006-2009 Master: Harbin Veterinary Research Institute, CAAS, Preventive Veterinary Medicine
- 2009-2012 PhD: China Agricultural University, Preventive Veterinary Medicine
- National Youth Talent Project Winner
- Introduced as 'Outstanding Talent' by China Agricultural University
Publications
- Species-specific cleavage of cGAS by picornavirus protease 3C disrupts mitochondria DNA-mediated immune sensing, Yan Y, Wu L, Yuan Y, Wang H, Yin H, Li M, Chai L, Liang R, Liu Y, Zhao D, Xing J, Li P, Li X, 2023
- Impact of intracellular innate immune receptors on immunometabolism, Chou WC, Rampanelli E, Li X, Ting JP, 2021
- Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon, Li X, Deng M, Petrucelli AS, Zhu C, Mo J, Zhang L, Tam JW, Ariel P, Zhao B, Zhang S, Ke H, Li P, Dokholyan NV, Duncan JA, Ting JP, 2019
- Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization, Li X, Shu C, Yi G, Chaton CT, Shelton CL, Diao J, Zuo X, Kao CC, Herr AB, Li P, 2013
- Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides, Li X, Liu J, Qi J, Gao F, Li Q, Li X, Zhang N, Xia C, Gao GF, 2011
- The mechanism of double-stranded DNA sensing through the cGAS-STING pathway, Shu C, Li X, Li P, 2014
- Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites, Guo H, Chou WC, Lai Y, Liang K, Tam JW, Brickey WJ, Chen L, Montgomery ND, Li X, Bohannon LM, Sung AD, Chao NJ, Peled JU, Gomes ALC, van den Brink MRM, French MJ, Macintyre AN, Sempowski GD, Tan X, Sartor RB, Lu K, Ting JP, 2020
Awards
- 2021: National Natural Science Foundation Talent Project
- 2019: Keystone Symposium 'Innate Immune Receptors' Travel Award
- 2011: International Research on Epidemiology of Zoonoses and Training for Young Researchers, Japan, Travel Award
- 2011: National Veterinary PhD Forum, Best Academic Award
- China Agricultural University Research Achievement Award
- China Agricultural University Outstanding Graduate
