Professor | Xin Li | Asia Growth Partners

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Name	Xin Li
Contact Information	xinli2021@cau.edu.cn
Language ability	English, Chinese
Province	Beijing

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Name

Xin Li

Contact Information

xinli2021@cau.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	China Agricultural University
Faculty	Veterinary Medicine
Academic Background & Achievements	2001-2006 Bachelor: Northeast Agricultural University, Veterinary Medicine 2006-2009 Master: Harbin Veterinary Research Institute, CAAS, Preventive Veterinary Medicine 2009-2012 PhD: China Agricultural University, Preventive Veterinary Medicine National Youth Talent Project Winner Introduced as 'Outstanding Talent' by China Agricultural University
Work Experience	2012-2014 - Texas A&M University, Department of Biochemistry and Biophysics, Postdoctoral Researcher 2014-2020 - University of North Carolina at Chapel Hill, Lineberger Cancer Center, Postdoctoral Researcher/Research Associate 2021-Present - China Agricultural University, College of Veterinary Medicine, Professor
Awards	2021: National Natural Science Foundation Talent Project 2019: Keystone Symposium 'Innate Immune Receptors' Travel Award 2011: International Research on Epidemiology of Zoonoses and Training for Young Researchers, Japan, Travel Award 2011: National Veterinary PhD Forum, Best Academic Award China Agricultural University Research Achievement Award China Agricultural University Outstanding Graduate

University/Lab Affiliation and Title

China Agricultural University

Faculty

Veterinary Medicine

Academic Background & Achievements

2001-2006 Bachelor: Northeast Agricultural University, Veterinary Medicine
2006-2009 Master: Harbin Veterinary Research Institute, CAAS, Preventive Veterinary Medicine
2009-2012 PhD: China Agricultural University, Preventive Veterinary Medicine
National Youth Talent Project Winner
Introduced as 'Outstanding Talent' by China Agricultural University

Work Experience

2012-2014 - Texas A&M University, Department of Biochemistry and Biophysics, Postdoctoral Researcher
2014-2020 - University of North Carolina at Chapel Hill, Lineberger Cancer Center, Postdoctoral Researcher/Research Associate
2021-Present - China Agricultural University, College of Veterinary Medicine, Professor

Awards

2021: National Natural Science Foundation Talent Project
2019: Keystone Symposium 'Innate Immune Receptors' Travel Award
2011: International Research on Epidemiology of Zoonoses and Training for Young Researchers, Japan, Travel Award
2011: National Veterinary PhD Forum, Best Academic Award
China Agricultural University Research Achievement Award
China Agricultural University Outstanding Graduate

Areas of Focus	Infection and immunity research focusing on natural immune pattern recognition receptors against viral infections Molecular mechanisms of viral escape from natural immune recognition
Publications	Species-specific cleavage of cGAS by picornavirus protease 3C disrupts mitochondria DNA-mediated immune sensing, Yan Y, Wu L, Yuan Y, Wang H, Yin H, Li M, Chai L, Liang R, Liu Y, Zhao D, Xing J, Li P, Li X, 2023 Impact of intracellular innate immune receptors on immunometabolism, Chou WC, Rampanelli E, Li X, Ting JP, 2021 Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon, Li X, Deng M, Petrucelli AS, Zhu C, Mo J, Zhang L, Tam JW, Ariel P, Zhao B, Zhang S, Ke H, Li P, Dokholyan NV, Duncan JA, Ting JP, 2019 Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization, Li X, Shu C, Yi G, Chaton CT, Shelton CL, Diao J, Zuo X, Kao CC, Herr AB, Li P, 2013 Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides, Li X, Liu J, Qi J, Gao F, Li Q, Li X, Zhang N, Xia C, Gao GF, 2011 The mechanism of double-stranded DNA sensing through the cGAS-STING pathway, Shu C, Li X, Li P, 2014 Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites, Guo H, Chou WC, Lai Y, Liang K, Tam JW, Brickey WJ, Chen L, Montgomery ND, Li X, Bohannon LM, Sung AD, Chao NJ, Peled JU, Gomes ALC, van den Brink MRM, French MJ, Macintyre AN, Sempowski GD, Tan X, Sartor RB, Lu K, Ting JP, 2020

Areas of Focus

Infection and immunity research focusing on natural immune pattern recognition receptors against viral infections
Molecular mechanisms of viral escape from natural immune recognition

Publications

Species-specific cleavage of cGAS by picornavirus protease 3C disrupts mitochondria DNA-mediated immune sensing, Yan Y, Wu L, Yuan Y, Wang H, Yin H, Li M, Chai L, Liang R, Liu Y, Zhao D, Xing J, Li P, Li X, 2023
Impact of intracellular innate immune receptors on immunometabolism, Chou WC, Rampanelli E, Li X, Ting JP, 2021
Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon, Li X, Deng M, Petrucelli AS, Zhu C, Mo J, Zhang L, Tam JW, Ariel P, Zhao B, Zhang S, Ke H, Li P, Dokholyan NV, Duncan JA, Ting JP, 2019
Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization, Li X, Shu C, Yi G, Chaton CT, Shelton CL, Diao J, Zuo X, Kao CC, Herr AB, Li P, 2013
Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides, Li X, Liu J, Qi J, Gao F, Li Q, Li X, Zhang N, Xia C, Gao GF, 2011
The mechanism of double-stranded DNA sensing through the cGAS-STING pathway, Shu C, Li X, Li P, 2014
Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites, Guo H, Chou WC, Lai Y, Liang K, Tam JW, Brickey WJ, Chen L, Montgomery ND, Li X, Bohannon LM, Sung AD, Chao NJ, Peled JU, Gomes ALC, van den Brink MRM, French MJ, Macintyre AN, Sempowski GD, Tan X, Sartor RB, Lu K, Ting JP, 2020

Infection Immunity Viral Infections Natural Immune Pattern Recognition Receptors Cgas-Sting Nod-Like Receptors Immune Regulation Molecular Mechanisms Viral Escape

Lingjun Zheng - Shanghai Jiao Tong University

Qin Zhao - Sichuan Agricultural University

Cai Dongjie - Sichuan Agricultural University

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