Upload Avatar (500 x 500)
Guang-Hui Liu
Zoology
Chinese Academy of Sciences
Beijing
Language: Chinese, English
Aging
Genetics
Epigenetics
Stem Cells
Gene Editing
Precision Medicine
Disease Mechanism
Regenerative Medicine
Gene Therapy
Artificial Intelligence
Areas of Focus
- Decoding genetic and epigenetic information of human aging
- Mechanism research and precision treatment of human diseases based on stem cell technology
- Development and application of new gene editing and gene therapy technologies
Work Experience
- 2007-2012 - The Scripps Research Institute and Salk Institute for Biological Studies - Research Associate
- 2012-2019 - Institute of Biophysics, Chinese Academy of Sciences - Researcher (PI)
- 2019-present - Institute of Zoology, Chinese Academy of Sciences - Researcher (PI)
Academic Background & Achievements
- 2002 - Bachelor of Science: Peking University
- 2007 - Doctor of Science: Institute of Biophysics, Chinese Academy of Sciences
- Achievement: Member of the Chinese Academy of Medical Sciences
Publications
- Metformin Decelerates Aging Clock in Male Monkeys, Yang Y, Lu X, Liu N, Ma S, Zhang H, Zhang Z, Yang K, Jiang M, Zheng Z, Qiao Y, Hu Q, Huang Y, Zhang Y, Xiong M, Liu L, Jiang X, Reddy P, Dong X, Xu F, Wang Q, Zhao Q, Lei J, Sun S, Jing Y, Li J, Cai Y, Fan Y, Yan K, Jing Y, Haghani A, Xing M, Zhang X, Zhu G, Song W, Horvath S, Esteban CR, Song M, Wang S, Zhao G, Li W, Belmonte JCI, Qu J*, Zhang W*, Liu GH*, 2024
- Aging induces region-specific dysregulation of hormone synthesis in the primate adrenal gland, Wang Q, Wang X, Liu B, Ma S, Zhang F, Sun S, Jing Y, Fan Y, Ding Y, Xiong M, Li J, Zhai Q, Zheng Y, Liu C, Xu G, Yang J, Wang S, Ye J, Belmonte JCI, Qu J*, Liu GH*, Zhang W*, 2024
- The Sirtuin-associated human senescence program converges on the activation of placenta-specific gene PAPPA, Bi S, Jiang X, Ji Q, Wang Z, Ren J, Wang S, Yu Y, Wang R, Liu Z, Liu J, Hu J, Sun Q, Wu Z, Diao Z, Li J, Sun L, Belmonte JCI, Zhang W*, Liu GH*, Qu J*, 2024
- CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver, Li HY, Wang M, Jiang X, Jing Y, Wu Z, He Y, Yan K, Sun S, Ma S, Wang S, Belmonte JCB, Qu J*, Zhang W*, Wei T*, Liu GH*, 2024
- CHIT1-positive microglia drive motor neuron aging in the primate spinal cord, Sun S, Li J, Wang S, Li J, Ren J, Bao Z, Sun L, Ma X, Zheng F, Ma S, Sun L, Wang M, Yu Y, Ma M, Wang Q, Chen Z, Ma H, Wang X, Wu Z, Zhang H, Yan K, Yang Y, Zhang Y, Zhang S, Lei J, Teng ZQ, Liu CM, Bai G, Wang YJ, Li J, Wang X, Zhao G, Jiang T, Belmonte JCI, Qu J*, Zhang W*, Liu GH*, 2023
Awards
- Ho Leung Ho Lee Foundation Science and Technology Innovation Award (2024)
- Outstanding Contribution Scientist in Stem Cells (2024)
- Top Ten Scientific Advances in China (2023)
