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Song Moshi
songmoshi@ioz.ac.cn
English, Chinese
Beijing
Chinese Academy of Sciences
Institute of Zoology
  • 2011 - Master's Degree in Medicine: Karolinska Institute, Sweden
  • 2015 - PhD in Science: Washington University in St. Louis, USA
  • Published 88 papers with over 6100 citations
  • Published 44 papers in high-impact journals in the last five years
  • Postdoctoral Research in Cardiovascular Studies: Stanford University, USA
  • 2018 - Present: Full-time at Institute of Zoology, Chinese Academy of Sciences, Head of Mitochondria and Disease Research Group
Mitochondrial regulation of cardiac aging and related diseases
  • Prophylactic supplementation with Lactobacillus reuteri or its metabolite GABA protects against acute ischemic cardiac injury., Wang J, Zhang H, Yuan H, Chen S, Yu Y, Zhang X, Gao Z, Du H, Li W, Wang Y, Xia P, Wang J*, Song M*., 2024
  • 4E-BP1 counteracts human mesenchymal stem cell senescence via maintaining mitochondrial homeostasis., He Y, Ji Q, Wu Z, Cai Y, Yin J, Zhang Y, Zhang S, Liu X, Zhang W, Liu GH*, Wang S*, Song M*, Qu J*., 2023
  • A biomarker framework for cardiac aging: the Aging Biomarker Consortium consensus statement., Aging Biomarker Consortium, Zhang W, Che Y, Tang X, Chen S, Song M*, Wang L*, Sun A*, Chen H*, Xu M*, Wang M*, Pu J*, Li Z*, Xiao J*, Cao C*, Zhang Y*, Lu Y*, Zhao Y*, Wang Y*, Zhang C*, Shen T*, Zhang W*, Tao L*, Qu J*, Tang Y*, Liu GH*, Pei G*, Li J*, Cao F*., 2023
  • The Aging Biomarker Consortium represents a new era for aging research in China., Ren J#, Song M#, Zhang W#, Cai JP, Cao F, Cao Z, Chan P, Chen C, Chen G, Chen HZ, Chen J, Chen XC, Ci W, Ding BS, Ding Q, Gao F, Gao S, Han JJ, He QY, Huang K, Ju Z, Kong QP, Li J, Li J, Li J, Li X, Liu B, Liu F, Liu JP, Liu L, Liu Q, Liu Q, Liu X, Liu Y, Luo X, Ma S, Ma X, Mao Z, Nie J, Peng Y, Qu J, Ren R, Song W, Songyang Z, Sun L, Sun YE, Sun Y, Tian M, Tian XL, Tian Y, Wang J, Wang S, Wang S, Wang W, Wang X, Wang X, Wang YJ, Wang Y, Wong CCL, Xiang AP, Xiao Y, Xiao ZX, Xie Z, Xiong W, Xu D, Yang Z, Ye J, Yu W, Yue R, Zhang C, Zhang H, Zhang L, Zhang X, Zhang Y, Zhang YW, Zhang Z, Zhao T, Zhao Y, Zhou Z, Zhu D, Zou W, Pei G, Liu GH., 2023
  • Gut microbial methionine impacts circadian clock gene expression and reactive oxygen species level in host gastrointestinal tract., Liu X, Ma Y, Yu Y, Zhang W, Shi J, Zhang X, Dai M, Wang Y, Zhang H, Zhang J, Shen J, Zhang F*, Song M*, Wang J*., 2023
  • Efficient Mining of Anticancer Peptides from Gut Metagenome., Ma Y, Liu X, Zhang X, Yu Y, Li Y, Song M*, Wang J*., 2023
  • Biomarkers of aging., Aging Biomarker Consortium; Bao H, Cao J, Chen M, Chen M, Chen W, Chen X, Chen Y, Chen Y, Chen Y, Chen Z, Chhetri JK, Ding Y, Feng J, Guo J, Guo M, He C, Jia Y, Jiang H, Jing Y, Li D, Li J, Li J, Liang Q, Liang R, Liu F, Liu X, Liu Z, Luo OJ, Lv J, Ma J, Mao K, Nie J, Qiao X, Sun X, Tang X, Wang J, Wang Q, Wang S, Wang X, Wang Y, Wang Y, Wu R, Xia K, Xiao FH, Xu L, Xu Y, Yan H, Yang L, Yang R, Yang Y, Ying Y, Zhang L, Zhang W, Zhang W, Zhang X, Zhang Z, Zhou M, Zhou R, Zhu Q, Zhu Z, Cao F*, Cao Z*, Chan P*, Chen C*, Chen G*, Chen HZ*, Chen J*, Ci W*, Ding BS*, Ding Q*, Gao F*, Han JJ*, Huang K*, Ju Z*, Kong QP*, Li J*, Li J*, Li X*, Liu B*, Liu F*, Liu L*, Liu Q*, Liu Q*, Liu X*, Liu Y*, Luo X*, Ma S*, Ma X*, Mao Z*, Nie J*, Peng Y*, Qu J*, Ren J*, Ren R*, Song M*, Songyang Z*, Sun YE*, Sun Y*, Tian M*, Wang S*, Wang S*, Wang X*, Wang X*, Wang YJ*, Wang Y*, Wong CCL*, Xiang AP*, Xiao Y*, Xie Z*, Xu D*, Ye J*, Yue R*, Zhang C*, Zhang H*, Zhang L*, Zhang W*, Zhang Y*, Zhang YW*, Zhang Z*, 2023
  • mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells., Chu Q, Liu F, He Y, Jiang X, Cai Y, Wu Z, Yan K, Geng L, Zhang Y, Feng H, Zhou K, Wang S, Zhang W, Liu GH*, Ma S*, Qu J*, Song M*., 2022
  • Destabilizing heterochromatin by APOE mediates senescence., Zhao H, Ji Q, Wu Z, Wang S, Ren J, Yan K, Wang Z, Hu J, Chu Q, Hu H, Cai Y, Wang Q, Huang D, Ji Z, Li J, Belmonte JCI, Song M*, Zhang W*, Qu J*, Liu GH*., 2022
  • Potential approaches for intervening aging., Shen J, Liu GH*, Song M*., 2022
  • Mesenteric lymph system constitutes the second route in gut-liver axis and transports metabolism-modulating gut microbial metabolites., Yu Y, Liu B, Liu X, Zhang X, Zhang W, Tian H, Shui G, Wang W, Song M*, Wang J*., 2022
  • Short- and long-read metagenomics expand individualized structural variations in gut microbiomes., Chen L, Zhao N, Cao J, Liu X, Xu J, Ma Y, Yu Y, Zhang X, Zhang W, Guan X, Yu X, Liu Z, Fan Y, Wang Y, Liang F, Wang D, Zhao L, Song M*, Wang J*., 2022
  • Low-dose chloroquine treatment extends the lifespan of aged rats., Li W, Zou Z, Cai Y, Yang K, Wang S, Liu Z, Geng L, Chu Q, Ji Z, Chan P, Liu GH*, Song M*, Qu J*, Zhang W*., 2022
  • The landscape of aging., Cai Y, Song W, Li J, Jing Y, Liang C, Zhang L, Zhang X, Zhang W, Liu B, An Y, Li J, Tang B, Pei S, Wu X, Liu Y, Zhuang CL, Ying Y, Dou X, Chen Y, Xiao FH, Li D, Yang R, Zhao Y, Wang Y, Wang L, Li Y, Ma S*, Wang S*, Song X*, Ren J*, Zhang L*, Wang J*, Zhang W*, Xie Z*, Qu J*, Wang J*, Xiao Y*, Tian Y*, Wang G*, Hu P*, Ye J*, Sun Y*, Mao Z*, Kong QP*, Liu Q*, Zou W*, Tian XL*, Xiao ZX*, Liu Y*, Liu JP*, Song M*, Han JJ*, Liu GH*., 2022
  • Single-cell transcriptomic atlas of primate cardiopulmonary aging., Ma S, Sun S, Li J, Fan Y, Qu J, Sun L, Wang S, Zhang Y, Yang S, Liu Z, Wu Z, Zhang S, Wang Q, Zheng A, Duo S, Yu Y, Belmonte JCI, Chan P, Zhou Q, Song M*, Zhang W*, Liu GH*., 2021
  • SIRT3 consolidates heterochromatin and counteracts senescence., Diao Z, Ji Q, Wu Z, Zhang W, Cai Y, Wang Z, Hu J, Liu Z, Wang Q, Bi S, Huang D, Ji Z, Liu GH*, Wang S*, Song M*, Qu J*., 2021
  • FOXO3-engineered human mesenchymal progenitor cells efficiently promote cardiac repair after myocardial infarction., Lei J, Wang S, Kang W, Chu Q, Liu Z, Sun L, Ji Y, Esteban CR, Yao Y, Belmonte JCI, Chan P, Liu GH*, Zhang W*, Song M*, Qu J*., 2021
  • Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging., Ma S, Sun S, Geng L, Song M, Wang W, Ye Y, Ji Q, Zou Z, Wang S, He X, Li W, Esteban CR, Long X, Guo G, Chan P, Zhou Q, Belmonte JCI, Zhang W, Qu J, Liu GH., 2020
  • SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer., Bi S, Liu Z, Wu Z, Wang Z, Liu X, Wang S, Ren J, Yao Y, Zhang W*, Song M*, Liu GH*, Qu J*., 2020
  • Treating osteoarthritis via gene therapy with rejuvenation factors., Zhang J, Liu GH*, Qu J*, Song M*., 2020
  • Mitochondrial regulation of cardiac aging., Wang Y, Li Y, He C, Gou B, Song M., 2019
  • Chemical screen identifies a geroprotective role of quercetin in premature aging., Geng L, Liu Z, Zhang W, Li W, Wu Z, Wang W, Ren R, Su Y, Wang P, Sun L, Ju Z, Chan P, Song M*, Qu J*, Liu GH*., 2019
  • Epigenetic Modifications in Cardiovascular Aging and Diseases., Zhang W, Song M, Qu J, Liu GH., 2018
  • CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-κB/RelA in maintaining the homeostasis of human vascular cells., Wang P, Liu Z, Zhang X, Li J, Sun L, Ju Z, Li J, Chan P, Liu GH*, Zhang W*, Song M*, Qu J*., 2018
  • Abrogating Mitochondrial Dynamics in Mouse Hearts Accelerates Mitochondrial Senescence., Song M, Franco A, Fleischer JA, Zhang L, Dorn GW 2nd., 2017
  • Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice., Gong G, Song M, Csordas G, Kelly DP, Matkovich SJ, Dorn GW 2nd., 2015
  • Mitoconfusion: noncanonical functioning of dynamism factors in static mitochondria of the heart., Song M, Dorn GW 2nd., 2015
  • Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts., Song M, Mihara K, Chen Y, Scorrano L, Dorn GW 2nd., 2015
  • Interdependence of Parkin-Mediated Mitophagy and Mitochondrial Fission in Adult Mouse Hearts., Song M, Gong G, Burelle Y, Gustafsson ÅB, Kitsis RN, Matkovich SJ, Dorn GW 2nd., 2015
  • Super-suppression of mitochondrial reactive oxygen species signaling impairs compensatory autophagy in primary mitophagic cardiomyopathy., Song M, Chen Y, Gong G, Murphy E, Rabinovitch PS, Dorn GW 2nd., 2014
Mitochondria Cardiac Aging Disease Mechanisms Intervention Strategies Molecular Mechanisms Biomarkers Heart Aging Research Biology

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