Professor | Liang Ma | Asia Growth Partners

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Name	Liang Ma
Contact Information	maliang@ioz.ac.cn
Language ability	Chinese, English
Province	Beijing

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Name

Liang Ma

Contact Information

maliang@ioz.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Chinese Academy of Sciences
Faculty	Institute of Zoology
Academic Background & Achievements	2015 - PhD: Chinese Academy of Sciences, Academy of Mathematics and Systems Science
Work Experience	2015-2019 - Assistant Researcher at Beijing Institute of Genomics, Chinese Academy of Sciences 2019-2023 - Assistant Researcher at Institute of Zoology, Chinese Academy of Sciences 2023-present - Associate Researcher at Institute of Zoology, Chinese Academy of Sciences

University/Lab Affiliation and Title

Chinese Academy of Sciences

Faculty

Institute of Zoology

Academic Background & Achievements

2015 - PhD: Chinese Academy of Sciences, Academy of Mathematics and Systems Science

Work Experience

2015-2019 - Assistant Researcher at Beijing Institute of Genomics, Chinese Academy of Sciences
2019-2023 - Assistant Researcher at Institute of Zoology, Chinese Academy of Sciences
2023-present - Associate Researcher at Institute of Zoology, Chinese Academy of Sciences

Areas of Focus	Computational Biology Bioinformatics
Publications	SONAR enables cell type deconvolution with spatially weighted Poisson-Gamma model for spatial transcriptomics., Liu, Z., Wu, D., Zhai, W., Ma, L., 2023 Population genomic analysis reveals distinct demographics and recent adaptation in the black flying fox (Pteropus alecto)., He, H., Yang, H., Foo, R., Chan, W., Zhu, F., Liu, Y., Zhou, X., Ma, L., Wang, L.F. and Zhai, W., 2023 RobustTree: An adaptive, robust PCA algorithm for embedded tree structure recovery from single-cell sequencing data., Chen, Z., Zhang, B., Gong, F., Wan, L., Ma, L., 2023 BiTSC2: Bayesian inference of tumor clonal tree by joint analysis of single-cell SNV and CNA data., Chen, Z., Gong, F., Wan, L. and Ma, L., 2022 DecOT: Bulk Deconvolution With Optimal Transport Loss Using a Single-Cell Reference., Liu, G., Liu, X. and Ma, L., 2022 Predicting Egg Passage Adaptations to Design Better Vaccines for the H3N2 Influenza Virus., Liu, Y., Chen, H., Duan, W., Zhang, X., He, X., Nielsen, R., Ma, L.* & Zhai, W., 2022 RobustClone: a robust PCA method for tumor clone and evolution inference from single-cell sequencing data., Chen, Z., Gong, F., Wan, L., and Ma, L., 2020 NeuralEE: A GPU-Accelerated Elastic Embedding Dimensionality Reduction Method for Visualizing Large-Scale scRNA-Seq Data., Xiong, J., Gong, F., Wan, L. and Ma, L., 2020 Epidemiology characteristics of the clonal complexes of Mycobacterium tuberculosis Lineage 4 in China., Ni, X., Zhu, C., Li, Q., Jiang, H., Liu, J., Chen, Z., He, L., Jia, J., Zhang, Z., Ma, L. and Li, W., 2020 Statistical test of structured continuous trees based on discordance matrix., Bai, X., Ma, L. and Wan, L., 2019 DensityPath: an algorithm to visualize and reconstruct cell state-transition path on density landscape for single-cell RNA sequencing data., Chen, Z., An, S., Bai, X., Gong, F., Ma, L. and Wan, L., 2019 TSEE: an elastic embedding method to visualize the dynamic gene expression patterns of time series single-cell RNA sequencing data., An, S., Ma, L. and Wan, L., 2019 Whole genome analyses of Chinese population and de novo assembly of a northern Han genome., Du, Z., Ma, L., Qu, H., Chen, W., ..., Xiao, J. and Zeng C., 2019 Multi-scale analysis of schizophrenia risk genes, brain structure, and clinical symptoms reveals integrative clues for subtyping schizophrenia patients., Ma, L., Rolls, E.T., Liu, X., Liu, Y., Jiao, Z., Wang, Y., Gong, W., Ma, Z., Gong, F. and Wan, L., 2019 AIM-SNPtag: A computationally efficient approach for developing ancestry-informative SNP panels., Zhao, S., Shi, C.M., Ma, L., Liu, Q., Liu, Y., Wu, F., Chi, L. and Chen, H., 2019 A branch point on differentiation trajectory is the bifurcating event revealed by dynamical network biomarker analysis of single-cell data., Chen, Z., Bai, X., Ma, L., Wang, X., Liu, X., Liu, Y., Chen, L.* and Wan, L., 2018 Inferring Chinese surnames with Y-STR profiles., Shi, C.M., Li, C., Ma, L., Chi, L., Zhao, J., Yuan, W., Zhou, Z., Yan, J.W. and Chen, H., 2018 Mycobacterium tuberculosis lineage distribution in Xinjiang and Gansu Provinces, China., Chen, H., He, L., Huang, H., Shi, C., Ni, X., Dai, G., Ma, L. and Li, W.*, 2017 Statistical measures of genetic differentiation of populations: Rationales, history and current states., Ma, L., Ji, Y.J. and Zhang, D.X., 2015 Factors affecting mito-nuclear codon usage interactions in the OXPHOS system of Drosophila melanogaster., Sun, Z., Ma, L., Murphy, R.W., Zhang, X. and Huang, D., 2008

Areas of Focus

Computational Biology
Bioinformatics

Publications

SONAR enables cell type deconvolution with spatially weighted Poisson-Gamma model for spatial transcriptomics., Liu, Z., Wu, D., Zhai, W.*, Ma, L.*, 2023
Population genomic analysis reveals distinct demographics and recent adaptation in the black flying fox (Pteropus alecto)., He, H., Yang, H., Foo, R., Chan, W., Zhu, F., Liu, Y., Zhou, X., Ma, L.*, Wang, L.F.* and Zhai, W.*, 2023
RobustTree: An adaptive, robust PCA algorithm for embedded tree structure recovery from single-cell sequencing data., Chen, Z., Zhang, B., Gong, F., Wan, L.*, Ma, L.*, 2023
BiTSC2: Bayesian inference of tumor clonal tree by joint analysis of single-cell SNV and CNA data., Chen, Z., Gong, F., Wan, L.* and Ma, L.*, 2022
DecOT: Bulk Deconvolution With Optimal Transport Loss Using a Single-Cell Reference., Liu, G., Liu, X.* and Ma, L.*, 2022
Predicting Egg Passage Adaptations to Design Better Vaccines for the H3N2 Influenza Virus., Liu, Y., Chen, H., Duan, W., Zhang, X., He, X., Nielsen, R.*, Ma, L.* & Zhai, W.*, 2022
RobustClone: a robust PCA method for tumor clone and evolution inference from single-cell sequencing data., Chen, Z., Gong, F., Wan, L.*, and Ma, L.*, 2020
NeuralEE: A GPU-Accelerated Elastic Embedding Dimensionality Reduction Method for Visualizing Large-Scale scRNA-Seq Data., Xiong, J., Gong, F., Wan, L.* and Ma, L.*, 2020
Epidemiology characteristics of the clonal complexes of Mycobacterium tuberculosis Lineage 4 in China., Ni, X., Zhu, C., Li, Q., Jiang, H., Liu, J., Chen, Z., He, L., Jia, J., Zhang, Z., Ma, L.* and Li, W.*, 2020
Statistical test of structured continuous trees based on discordance matrix., Bai, X., Ma, L.* and Wan, L.*, 2019
DensityPath: an algorithm to visualize and reconstruct cell state-transition path on density landscape for single-cell RNA sequencing data., Chen, Z., An, S., Bai, X., Gong, F., Ma, L.* and Wan, L.*, 2019
TSEE: an elastic embedding method to visualize the dynamic gene expression patterns of time series single-cell RNA sequencing data., An, S., Ma, L.* and Wan, L.*, 2019
Whole genome analyses of Chinese population and de novo assembly of a northern Han genome., Du, Z., Ma, L., Qu, H., Chen, W., ..., Xiao, J.* and Zeng C.*, 2019
Multi-scale analysis of schizophrenia risk genes, brain structure, and clinical symptoms reveals integrative clues for subtyping schizophrenia patients., Ma, L., Rolls, E.T., Liu, X., Liu, Y., Jiao, Z., Wang, Y., Gong, W., Ma, Z., Gong, F. and Wan, L., 2019
AIM-SNPtag: A computationally efficient approach for developing ancestry-informative SNP panels., Zhao, S., Shi, C.M., Ma, L., Liu, Q., Liu, Y., Wu, F., Chi, L. and Chen, H., 2019
A branch point on differentiation trajectory is the bifurcating event revealed by dynamical network biomarker analysis of single-cell data., Chen, Z., Bai, X., Ma, L.*, Wang, X., Liu, X., Liu, Y., Chen, L.* and Wan, L.*, 2018
Inferring Chinese surnames with Y-STR profiles., Shi, C.M., Li, C., Ma, L., Chi, L., Zhao, J., Yuan, W., Zhou, Z., Yan, J.W.* and Chen, H.*, 2018
Mycobacterium tuberculosis lineage distribution in Xinjiang and Gansu Provinces, China., Chen, H., He, L., Huang, H., Shi, C., Ni, X., Dai, G., Ma, L.* and Li, W.*, 2017
Statistical measures of genetic differentiation of populations: Rationales, history and current states., Ma, L., Ji, Y.J. and Zhang, D.X., 2015
Factors affecting mito-nuclear codon usage interactions in the OXPHOS system of Drosophila melanogaster., Sun, Z., Ma, L., Murphy, R.W., Zhang, X. and Huang, D., 2008

Molecular Evolution Population Genetics Single-Cell Analysis Spatial Genomics Data Modeling Analysis Methods Genotype Phenotype Evolution Diversity

Qiao Gexia - Chinese Academy of Sciences

Jing Chen - Chinese Academy of Sciences

Huang Zushi - Chinese Academy of Sciences

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