Areas of Focus
- Biochemistry, Molecular Biology, Structural Biology, and Cell Biology
Work Experience
- 2009-2021 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Assistant Researcher, Associate Researcher, Researcher
- 2021-Present - Shanghai University School of Medicine - Researcher
Academic Background & Achievements
- 1998-2002 Bachelor's Degree: Nanjing University
- 2003-2009 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
- Published over 30 academic papers
- First author or corresponding author in high-impact journals such as Cell Research, Molecular Cell, Nature Communications, and Science Advances
Publications
- Molecular mechanism of the S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling, X. Tang, Y. Zhang, G. Wang, C. Zhang, F. Wang, J. Shi, T. Zhang, J. Ding, 2022
- Identification and Tetramer Structure of Hemin-Binding Protein SPD_0310 Linked to Iron Homeostasis and Virulence of Streptococcus pneumoniae, K. Cao, T. Zhang, Nan Li, X. Yang, J. Ding, Q. He, X. Sun, 2022
- Nde1 is a Rab9 effector for loading late endosomes to cytoplasmic dynein motor complex, Y. Zhang, Z. Chen, F. Wang, H. Sun, X. Zhu, J. Ding, T. Zhang, 2022
- Structural basis for self-cleavage prevention by tag:anti-tag pairing complementary in type VI Cas13 CRISPR systems, B. Wang, T. Zhang, J. Yin, Y. Yu, W. Xu, J. Ding, D. J. Patel, H. Yang, 2021
- Crystal structures of algal TET homologue CMD1 provide insight into the molecular mechanism for vitamin C-derived C5-glyceryl-methylcytosine DNA modification, W. Li, T. Zhang, M. Sun, Y. Shi, X. Zhang, G. Xu, J. Ding, 2021
- Structural insights into the EGO-TC-mediated membrane tethering of the TORC1-regulatory Rag GTPases, T. Zhang, M.P. Péli-Gulli, Z. Zhang, X. Tang, J. Ye, C. De Virgilio, J. Ding, 2019
- Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1, T. Zhang, R. Wang, Z. Wang, X. Wang, F. Wang, J. Ding, 2017
- Structural basis for targeting BIG1 to Golgi apparatus through interaction of its DCB domain with Arl1, R. Wang, Z. Wang, K. Wang, T. Zhang, J. Ding, 2016
- Structural insight into the arginine-binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling, J. Xia, R. Wang, T. Zhang, J. Ding, 2016
- Crystal structure of the Ego1-Ego2-Ego3 complex and its role in promoting Rag GTPase-dependent TORC1 signaling, K. Powis, T. Zhang, N. Panchaud, R. Wang, C. De Virgilio, J. Ding, 2015
Awards
- Selected for the Youth Innovation Promotion Association of the Chinese Academy of Sciences
- Received the Sanofi-Shanghai Institute for Biological Sciences Excellent Young Talent Award
