Professor | Tianlong Zhang | Asia Growth Partners

Name	Tianlong Zhang
Language ability	Chinese, English
Province	Shanghai

Name

Tianlong Zhang

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Shanghai University
Faculty	Medicine
Academic Background & Achievements	1998-2002 Bachelor's Degree: Nanjing University 2003-2009 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences Published over 30 academic papers First author or corresponding author in high-impact journals such as Cell Research, Molecular Cell, Nature Communications, and Science Advances
Work Experience	2009-2021 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Assistant Researcher, Associate Researcher, Researcher 2021-Present - Shanghai University School of Medicine - Researcher
Awards	Selected for the Youth Innovation Promotion Association of the Chinese Academy of Sciences Received the Sanofi-Shanghai Institute for Biological Sciences Excellent Young Talent Award

University/Lab Affiliation and Title

Shanghai University

Faculty

Medicine

Academic Background & Achievements

1998-2002 Bachelor's Degree: Nanjing University
2003-2009 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Published over 30 academic papers
First author or corresponding author in high-impact journals such as Cell Research, Molecular Cell, Nature Communications, and Science Advances

Work Experience

2009-2021 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Assistant Researcher, Associate Researcher, Researcher
2021-Present - Shanghai University School of Medicine - Researcher

Awards

Selected for the Youth Innovation Promotion Association of the Chinese Academy of Sciences
Received the Sanofi-Shanghai Institute for Biological Sciences Excellent Young Talent Award

Areas of Focus	Biochemistry, Molecular Biology, Structural Biology, and Cell Biology
Publications	Molecular mechanism of the S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling, X. Tang, Y. Zhang, G. Wang, C. Zhang, F. Wang, J. Shi, T. Zhang, J. Ding, 2022 Identification and Tetramer Structure of Hemin-Binding Protein SPD_0310 Linked to Iron Homeostasis and Virulence of Streptococcus pneumoniae, K. Cao, T. Zhang, Nan Li, X. Yang, J. Ding, Q. He, X. Sun, 2022 Nde1 is a Rab9 effector for loading late endosomes to cytoplasmic dynein motor complex, Y. Zhang, Z. Chen, F. Wang, H. Sun, X. Zhu, J. Ding, T. Zhang, 2022 Structural basis for self-cleavage prevention by tag:anti-tag pairing complementary in type VI Cas13 CRISPR systems, B. Wang, T. Zhang, J. Yin, Y. Yu, W. Xu, J. Ding, D. J. Patel, H. Yang, 2021 Crystal structures of algal TET homologue CMD1 provide insight into the molecular mechanism for vitamin C-derived C5-glyceryl-methylcytosine DNA modification, W. Li, T. Zhang, M. Sun, Y. Shi, X. Zhang, G. Xu, J. Ding, 2021 Structural insights into the EGO-TC-mediated membrane tethering of the TORC1-regulatory Rag GTPases, T. Zhang, M.P. Péli-Gulli, Z. Zhang, X. Tang, J. Ye, C. De Virgilio, J. Ding, 2019 Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1, T. Zhang, R. Wang, Z. Wang, X. Wang, F. Wang, J. Ding, 2017 Structural basis for targeting BIG1 to Golgi apparatus through interaction of its DCB domain with Arl1, R. Wang, Z. Wang, K. Wang, T. Zhang, J. Ding, 2016 Structural insight into the arginine-binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling, J. Xia, R. Wang, T. Zhang, J. Ding, 2016 Crystal structure of the Ego1-Ego2-Ego3 complex and its role in promoting Rag GTPase-dependent TORC1 signaling, K. Powis, T. Zhang, N. Panchaud, R. Wang, C. De Virgilio, J. Ding, 2015

Areas of Focus

Biochemistry, Molecular Biology, Structural Biology, and Cell Biology

Publications

Molecular mechanism of the S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling, X. Tang, Y. Zhang, G. Wang, C. Zhang, F. Wang, J. Shi, T. Zhang, J. Ding, 2022
Identification and Tetramer Structure of Hemin-Binding Protein SPD_0310 Linked to Iron Homeostasis and Virulence of Streptococcus pneumoniae, K. Cao, T. Zhang, Nan Li, X. Yang, J. Ding, Q. He, X. Sun, 2022
Nde1 is a Rab9 effector for loading late endosomes to cytoplasmic dynein motor complex, Y. Zhang, Z. Chen, F. Wang, H. Sun, X. Zhu, J. Ding, T. Zhang, 2022
Structural basis for self-cleavage prevention by tag:anti-tag pairing complementary in type VI Cas13 CRISPR systems, B. Wang, T. Zhang, J. Yin, Y. Yu, W. Xu, J. Ding, D. J. Patel, H. Yang, 2021
Crystal structures of algal TET homologue CMD1 provide insight into the molecular mechanism for vitamin C-derived C5-glyceryl-methylcytosine DNA modification, W. Li, T. Zhang, M. Sun, Y. Shi, X. Zhang, G. Xu, J. Ding, 2021
Structural insights into the EGO-TC-mediated membrane tethering of the TORC1-regulatory Rag GTPases, T. Zhang, M.P. Péli-Gulli, Z. Zhang, X. Tang, J. Ye, C. De Virgilio, J. Ding, 2019
Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1, T. Zhang, R. Wang, Z. Wang, X. Wang, F. Wang, J. Ding, 2017
Structural basis for targeting BIG1 to Golgi apparatus through interaction of its DCB domain with Arl1, R. Wang, Z. Wang, K. Wang, T. Zhang, J. Ding, 2016
Structural insight into the arginine-binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling, J. Xia, R. Wang, T. Zhang, J. Ding, 2016
Crystal structure of the Ego1-Ego2-Ego3 complex and its role in promoting Rag GTPase-dependent TORC1 signaling, K. Powis, T. Zhang, N. Panchaud, R. Wang, C. De Virgilio, J. Ding, 2015

Biochemistry Molecular Biology Structural Biology Cell Biology Aging Cancer Diabetes Signal Pathways Drug Targets Molecular Mechanisms

Tianlong Zhang - Shanghai University

Xiaodong Sun - Shanghai University

Liyan Xiong - Shanghai University

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