Professor | Tianlong Zhang | Asia Growth Partners

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Name	Tianlong Zhang
Language ability	Chinese, English
Province	Shanghai

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Name

Tianlong Zhang

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Shanghai University
Faculty	Medicine
Academic Background & Achievements	1998-2002 Bachelor's Degree: Nanjing University 2003-2009 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences Published over 30 academic papers First author or corresponding author in high-impact journals Recipient of national and academy-level research grants
Work Experience	2009-2021 Assistant Researcher, Associate Researcher, Researcher at Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences 2021-Present Researcher at Shanghai University Medical School
Awards	Member of the Youth Innovation Promotion Association, Chinese Academy of Sciences Recipient of the Sanofi-Beauty Young Talent Award

University/Lab Affiliation and Title

Shanghai University

Faculty

Medicine

Academic Background & Achievements

1998-2002 Bachelor's Degree: Nanjing University
2003-2009 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Published over 30 academic papers
First author or corresponding author in high-impact journals
Recipient of national and academy-level research grants

Work Experience

2009-2021 Assistant Researcher, Associate Researcher, Researcher at Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
2021-Present Researcher at Shanghai University Medical School

Awards

Member of the Youth Innovation Promotion Association, Chinese Academy of Sciences
Recipient of the Sanofi-Beauty Young Talent Award

Areas of Focus	Biochemistry, Molecular Biology, Structural Biology, and Cell Biology Research on signaling pathways related to aging, cancer, and diabetes Study of molecular mechanisms and drug target discovery
Publications	Molecular mechanism of the S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling, X. Tang, Y. Zhang, G. Wang, C. Zhang, F. Wang, J. Shi, T. Zhang, J. Ding Identification and Tetramer Structure of Hemin-Binding Protein SPD_0310 Linked to Iron Homeostasis and Virulence of Streptococcus pneumoniae, K. Cao, T. Zhang, Nan Li, X. Yang, J. Ding, Q. He, X. Sun Nde1 is a Rab9 effector for loading late endosomes to cytoplasmic dynein motor complex, Y. Zhang, Z. Chen, F. Wang, H. Sun, X. Zhu, J. Ding, T. Zhang Structural basis for self-cleavage prevention by tag:anti-tag pairing complementary in type VI Cas13 CRISPR systems, B. Wang, T. Zhang, J. Yin, Y. Yu, W. Xu, J. Ding, D. J. Patel, H. Yang Crystal structures of algal TET homologue CMD1 provide insight into the molecular mechanism for vitamin C-derived C5-glyceryl-methylcytosine DNA modification, W. Li, T. Zhang, M. Sun, Y. Shi, X. Zhang, G. Xu, J. Ding Structural insights into the EGO-TC-mediated membrane tethering of the TORC1-regulatory Rag GTPases, T. Zhang, M.P. Péli-Gulli, Z. Zhang, X. Tang, J. Ye, C. De Virgilio, J. Ding Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1, T. Zhang, R. Wang, Z. Wang, X. Wang, F. Wang, J. Ding Structural basis for targeting BIG1 to Golgi apparatus through interaction of its DCB domain with Arl1, R. Wang, Z. Wang, K. Wang, T. Zhang, J. Ding Structural insight into the arginine-binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling, J. Xia, R. Wang, T. Zhang, J. Ding Crystal structure of the Ego1-Ego2-Ego3 complex and its role in promoting Rag GTPase-dependent TORC1 signaling, K. Powis, T. Zhang, N. Panchaud, R. Wang, C. De Virgilio, J. Ding

Areas of Focus

Biochemistry, Molecular Biology, Structural Biology, and Cell Biology
Research on signaling pathways related to aging, cancer, and diabetes
Study of molecular mechanisms and drug target discovery

Publications

Molecular mechanism of the S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling, X. Tang, Y. Zhang, G. Wang, C. Zhang, F. Wang, J. Shi, T. Zhang, J. Ding
Identification and Tetramer Structure of Hemin-Binding Protein SPD_0310 Linked to Iron Homeostasis and Virulence of Streptococcus pneumoniae, K. Cao, T. Zhang, Nan Li, X. Yang, J. Ding, Q. He, X. Sun
Nde1 is a Rab9 effector for loading late endosomes to cytoplasmic dynein motor complex, Y. Zhang, Z. Chen, F. Wang, H. Sun, X. Zhu, J. Ding, T. Zhang
Structural basis for self-cleavage prevention by tag:anti-tag pairing complementary in type VI Cas13 CRISPR systems, B. Wang, T. Zhang, J. Yin, Y. Yu, W. Xu, J. Ding, D. J. Patel, H. Yang
Crystal structures of algal TET homologue CMD1 provide insight into the molecular mechanism for vitamin C-derived C5-glyceryl-methylcytosine DNA modification, W. Li, T. Zhang, M. Sun, Y. Shi, X. Zhang, G. Xu, J. Ding
Structural insights into the EGO-TC-mediated membrane tethering of the TORC1-regulatory Rag GTPases, T. Zhang, M.P. Péli-Gulli, Z. Zhang, X. Tang, J. Ye, C. De Virgilio, J. Ding
Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1, T. Zhang, R. Wang, Z. Wang, X. Wang, F. Wang, J. Ding
Structural basis for targeting BIG1 to Golgi apparatus through interaction of its DCB domain with Arl1, R. Wang, Z. Wang, K. Wang, T. Zhang, J. Ding
Structural insight into the arginine-binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling, J. Xia, R. Wang, T. Zhang, J. Ding
Crystal structure of the Ego1-Ego2-Ego3 complex and its role in promoting Rag GTPase-dependent TORC1 signaling, K. Powis, T. Zhang, N. Panchaud, R. Wang, C. De Virgilio, J. Ding

Biochemistry Molecular Biology Structural Biology Cell Biology Aging Cancer Diabetes Signaling Pathways Molecular Mechanisms Drug Targets

Tianlong Zhang - Shanghai University

Xiaodong Sun - Shanghai University

Liyan Xiong - Shanghai University

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