Professor | Panpan Hou | Asia Growth Partners

Name	Panpan Hou
Contact Information	houpp@mail.sysu.edu.cn
Language ability	Chinese, English
Province	Guangdong

Name

Panpan Hou

Contact Information

houpp@mail.sysu.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Guangzhou Medical University
Faculty	Basic Medical Sciences

University/Lab Affiliation and Title

Guangzhou Medical University

Faculty

Basic Medical Sciences

Areas of Focus	Major respiratory infections and lung injury Pathogenic mechanisms of important respiratory RNA virus infections
Publications	CCDC50 promotes tumor growth through regulation of lysosome homeostasis, Penghui Jia, Tian Tian, Zibo Li, Yicheng Wang, Yuxin Lin, Weijie Zeng, Yu Ye, Miao He, Xiangrong Ni, Ji’an Pan, Xiaonan Dong, Jian Huang, Chun-mei Li, Deyin Guo & Panpan Hou, 2023 CCDC50 suppresses NLRP3 inflammasome activity by mediating autophagic degradation of NLRP3, Yuxin Lin, Zibo Li, Yicheng Wang, Tian Tian, Penghui Jia, Yu Ye, Miao He, Zixiao Yang, Chunmei Li, Deyin Guo & Panpan Hou, 2022 A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection, Panpan Hou, Kongxiang Yang, Penghui Jia, Lan Liu, Yuxin Lin, Zibo Li, Jun Li, Shuliang Chen, Shuting Guo, Ji’An Pan, Junyu Wu, Hong Peng, Weijie Zeng, Chunmei Li, Yingfang Liu and Deyin Guo, 2021 An unconventional role of an ASB family protein in NF-κB activation and inflammatory response during microbial infection and colitis, Panpan Hou, Penghui Jia, Kongxiang Yang, Zibo Li, Tian Tian, Yuxin Lin, Weijie Zeng, Fan Xing, Yu Chen, Chunmei Li, Yingfang Liu & Deyin Guo, 2021 Autophagy receptor CCDC50 tunes STING-mediated interferon response in viral infection and autoimmune disease, Panpan Hou, Yuxin Lin, Zibo Li, Tian Tian, Yicheng Wang, Penghui Jia, Xi Zhang, Liu Cao, Chunmei Li, Jieruo Gu & Deyin Guo, 2021 A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220, Panpan Hou, Chao Wu, Yuchen Wang, Rui Qi, Dheeraj Bhavanasi, Zhixiang Zuo, Cedric Dos Santos, Shuliang Chen, Yu Chen, Hong Zheng, Hong Wang, Alexander Perl, Deyin Guo, Jian Huang, 2017 The regulation of NLRP3 inflammasome activation by CCDC50-mediated autophagy, Panpan Hou, Tian Tian, Penghui Jia, Yuxin Lin, Zibo Li, Yicheng Wang, Yu Ye, Chunmei Li, Deyin Guo, 2022

Areas of Focus

Major respiratory infections and lung injury
Pathogenic mechanisms of important respiratory RNA virus infections

Publications

CCDC50 promotes tumor growth through regulation of lysosome homeostasis, Penghui Jia, Tian Tian, Zibo Li, Yicheng Wang, Yuxin Lin, Weijie Zeng, Yu Ye, Miao He, Xiangrong Ni, Ji’an Pan, Xiaonan Dong, Jian Huang, Chun-mei Li, Deyin Guo & Panpan Hou, 2023
CCDC50 suppresses NLRP3 inflammasome activity by mediating autophagic degradation of NLRP3, Yuxin Lin, Zibo Li, Yicheng Wang, Tian Tian, Penghui Jia, Yu Ye, Miao He, Zixiao Yang, Chunmei Li, Deyin Guo & Panpan Hou, 2022
A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection, Panpan Hou, Kongxiang Yang, Penghui Jia, Lan Liu, Yuxin Lin, Zibo Li, Jun Li, Shuliang Chen, Shuting Guo, Ji’An Pan, Junyu Wu, Hong Peng, Weijie Zeng, Chunmei Li, Yingfang Liu and Deyin Guo, 2021
An unconventional role of an ASB family protein in NF-κB activation and inflammatory response during microbial infection and colitis, Panpan Hou, Penghui Jia, Kongxiang Yang, Zibo Li, Tian Tian, Yuxin Lin, Weijie Zeng, Fan Xing, Yu Chen, Chunmei Li, Yingfang Liu & Deyin Guo, 2021
Autophagy receptor CCDC50 tunes STING-mediated interferon response in viral infection and autoimmune disease, Panpan Hou, Yuxin Lin, Zibo Li, Tian Tian, Yicheng Wang, Penghui Jia, Xi Zhang, Liu Cao, Chunmei Li, Jieruo Gu & Deyin Guo, 2021
A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220, Panpan Hou, Chao Wu, Yuchen Wang, Rui Qi, Dheeraj Bhavanasi, Zhixiang Zuo, Cedric Dos Santos, Shuliang Chen, Yu Chen, Hong Zheng, Hong Wang, Alexander Perl, Deyin Guo, Jian Huang, 2017
The regulation of NLRP3 inflammasome activation by CCDC50-mediated autophagy, Panpan Hou, Tian Tian, Penghui Jia, Yuxin Lin, Zibo Li, Yicheng Wang, Yu Ye, Chunmei Li, Deyin Guo, 2022

Respiratory Infections Lung Injury Rna Virus Pathogenic Mechanisms Autophagy Nlrp3 Inflammasome Tumor Growth Lysosome Homeostasis Interferon Response Microbial Infection

Shaofei Wang - Fudan University

Zhimin Long - Chongqing Medical University

Cha-Xiang Guan - Central South University

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