Areas of Focus
- Major respiratory infections and lung injury
- Pathogenic mechanisms of important respiratory RNA virus infections
Publications
- CCDC50 promotes tumor growth through regulation of lysosome homeostasis, Penghui Jia, Tian Tian, Zibo Li, Yicheng Wang, Yuxin Lin, Weijie Zeng, Yu Ye, Miao He, Xiangrong Ni, Ji’an Pan, Xiaonan Dong, Jian Huang, Chun-mei Li, Deyin Guo & Panpan Hou, 2023
- CCDC50 suppresses NLRP3 inflammasome activity by mediating autophagic degradation of NLRP3, Yuxin Lin, Zibo Li, Yicheng Wang, Tian Tian, Penghui Jia, Yu Ye, Miao He, Zixiao Yang, Chunmei Li, Deyin Guo & Panpan Hou, 2022
- A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection, Panpan Hou, Kongxiang Yang, Penghui Jia, Lan Liu, Yuxin Lin, Zibo Li, Jun Li, Shuliang Chen, Shuting Guo, Ji’An Pan, Junyu Wu, Hong Peng, Weijie Zeng, Chunmei Li, Yingfang Liu and Deyin Guo, 2021
- An unconventional role of an ASB family protein in NF-κB activation and inflammatory response during microbial infection and colitis, Panpan Hou, Penghui Jia, Kongxiang Yang, Zibo Li, Tian Tian, Yuxin Lin, Weijie Zeng, Fan Xing, Yu Chen, Chunmei Li, Yingfang Liu & Deyin Guo, 2021
- Autophagy receptor CCDC50 tunes STING-mediated interferon response in viral infection and autoimmune disease, Panpan Hou, Yuxin Lin, Zibo Li, Tian Tian, Yicheng Wang, Penghui Jia, Xi Zhang, Liu Cao, Chunmei Li, Jieruo Gu & Deyin Guo, 2021
- A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220, Panpan Hou, Chao Wu, Yuchen Wang, Rui Qi, Dheeraj Bhavanasi, Zhixiang Zuo, Cedric Dos Santos, Shuliang Chen, Yu Chen, Hong Zheng, Hong Wang, Alexander Perl, Deyin Guo, Jian Huang, 2017
- The regulation of NLRP3 inflammasome activation by CCDC50-mediated autophagy, Panpan Hou, Tian Tian, Penghui Jia, Yuxin Lin, Zibo Li, Yicheng Wang, Yu Ye, Chunmei Li, Deyin Guo, 2022
