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Shaofei Wang
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Protein Homeostasis
Disease Development
Immune Checkpoint
Tumor Immunotherapy
Nlrp3 Inflammasome
Renal Injury
Fibrosis
Autophagy
Neurotoxicity
Lung Cancer
Areas of Focus
- Protein Homeostasis Imbalance and Disease Development
- Immune Checkpoint Molecules and Tumor Immunotherapy
Work Experience
- 2017-2019 - University of Pennsylvania School of Medicine - Postdoctoral Researcher in Systems Pharmacology and Translational Therapeutics
- 2020-present - Fudan University - Junior Associate Researcher in the Department of Cell and Genetic Medicine
Academic Background & Achievements
- 2007-2012 Bachelor in Veterinary Medicine: Jilin University
- 2012-2017 Ph.D. in Medicinal Chemistry: Fudan University
Publications
- Interleukin-22 attenuated renal tubular injury in aristolochic acid nephropathy via suppressing activation of NLRP3 inflammasome, Wang S, Fan J, Mei X, Luan J, Li Y, Zhang X, Chen W, Wang Y, Meng G, Ju D, 2019
- Interleukin-22 ameliorated renal injury and fibrosis in diabetic nephropathy through inhibition of NLRP3 inflammasome activation, Wang S, Li Y, Fan J, Zhang X, Luan J, Bian Q, Ding T, Wang Y, Wang Z, Song P, Cui D, Mei X, Ju D, 2017
- The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers, Wang S, Li Y, Fan J, Wang Z, Zeng X, Sun Y, Song P, Ju D, 2014
- Regulating autophagy facilitated therapeutic efficacy of sonic hedgehog pathway inhibition on lung adenocarcinoma through GLI2 suppression and ROS production, Fan J, Zhang X, Wang S, Chen W, Li Y, Zeng X, Wang Y, Luan J, Li L, Sun X, Shen B, Ju D, 2019
- Targeting CD47 and autophagy elicited enhanced anti-tumor effects in non-small cell lung cancer, Zhang X, Fan J, Wang S, Li Y, Wang Y, Li S, Luan J, Wang Z, Song P, Chen Q, Tian W, Ju D, 2017
Awards
- 2020: Shanghai Sailing Program, Shanghai Science and Technology Commission
