Professor | Zhongmin Yuan | Asia Growth Partners

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Name	Zhongmin Yuan
Contact Information	yzm@gzhmu.edu.cn
Language ability	English, Chinese
Province	Guangdong

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Name

Zhongmin Yuan

Contact Information

yzm@gzhmu.edu.cn

Language ability

English, Chinese

Province

Guangdong

University/Lab Affiliation and Title	Guangzhou Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2002/9–2008/6 Master and PhD in Pharmacology: Sun Yat-sen University
Work Experience	2008/7-Present - Guangzhou Medical University, Institute of Neuroscience - Lecturer, Associate Professor, Researcher 2012/9-2014/3 - Studied abroad at Louisiana State University and Southern Illinois University
Awards	2012: Guangdong Provincial Government, Science and Technology Award, First Prize 2012: Ministry of Education, Natural Science, First Prize 2011: Guangzhou Medical Association, Excellent Paper Third Prize 2017: Guangzhou Medical Association, Excellent Paper Second Prize 2019: Guangzhou Medical Association, Excellent Paper Second Prize 2020: Guangzhou Medical Association, Excellent Paper Second Prize 2020: Guangzhou Medical Association, Excellent Paper Third Prize

University/Lab Affiliation and Title

Guangzhou Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2002/9–2008/6 Master and PhD in Pharmacology: Sun Yat-sen University

Work Experience

2008/7-Present - Guangzhou Medical University, Institute of Neuroscience - Lecturer, Associate Professor, Researcher
2012/9-2014/3 - Studied abroad at Louisiana State University and Southern Illinois University

Awards

2012: Guangdong Provincial Government, Science and Technology Award, First Prize
2012: Ministry of Education, Natural Science, First Prize
2011: Guangzhou Medical Association, Excellent Paper Third Prize
2017: Guangzhou Medical Association, Excellent Paper Second Prize
2019: Guangzhou Medical Association, Excellent Paper Second Prize
2020: Guangzhou Medical Association, Excellent Paper Second Prize
2020: Guangzhou Medical Association, Excellent Paper Third Prize

Areas of Focus	Signal transduction, gene regulation, and epigenetic mechanisms in neuronal apoptosis during hemorrhagic stroke Pathogenesis and prevention of neuro-oncology and neuroimmune diseases
Publications	CD8+ T-cell predominance in autoimmune glial fibrillary acidic protein astrocytopathy, Zhongmin Yuan, Huilu Li, Lu Huang, Congcong Fu, Yaotang Chen, Cheng Zhi, Wei Qiu, Youming Long, 2021 Inhibition of HDAC4 Attenuated JNK/c-Jun-Dependent Neuronal Apoptosis and Early Brain Injury Following Subarachnoid Hemorrhage by Transcriptionally Suppressing MKK7, Liqiang Wu, Shulian Zeng, Yali Cao, Ziyan Huang, Sisi Liu, Huaidong Peng, Cheng Zhi, Shanshan Ma, Kunhua Hu, Zhongmin Yuan, 2019 Histone deacetylase 6 promotes growth of glioblastoma through the MKK7/JNK/c-Jun signaling pathway, Ziyan Huang, Yong Xia, Kunhua Hu, Shulian Zeng, Liqiang Wu, Sisi Liu, Cheng Zhi, Miaoling Lai, Danmin Chen, Longchang Xie, Zhongmin Yuan, 2020 MKK7 transcription positively or negatively regulated by SP1 and KLF5 depends on HDAC4 activity in glioma, Yezhong Wang, Yong Xia, Kunhua Hu, Minling Zeng, Cheng Zhi, Miaoling Lai, Liqiang Wu, Sisi Liu, Shulian Zeng, Ziyan Huang, Shanshan Ma, Zhongmin Yuan, 2019 Loss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim, Yanna Wu, Shanshan Ma, Yong Xia, Yangpeng Lu, Shiyin Xiao, Yali Cao, Sidian Zhuang, Xiangpeng Tan, Qiang Fu, Longchang Xie, Zhiming Li, Zhongmin Yuan, 2017 Essential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine, Ke Zhang, Ting Xu, Zhongmin Yuan, Zhisheng Wei, Vitor Nagai Yamaki, Mingfa Huang, Richard L Huganir, Xiang Cai, 2016 HDAC inhibitors suppress c-Jun/Fra-1-mediated proliferation through transcriptionally downregulating MKK7 and Raf1 in neuroblastoma cells, Weiwen He, Yanna Wu, Xiaomei Tang, Yong Xia, Guozhen He, Zhiqun Min, Chun Li, Shiqiu Xiong, Zhi Shi, Yongjian Lu, Zhongmin Yuan, 2016 Opposing roles for E2F1 in survival and death of cerebellar granule neurons, Yuan Z, Yao L, Li M, Liu S, He W, Lu Y, 2011 Opposing roles for ATF2 and c-Fos in c-Jun-mediated neuronal apoptosis, Yuan Z, Gong S, Luo J, Zheng Z, Song B, Ma S, Guo J, Hu C, Thiel G, Vinson C, Hu CD, Wang Y, Li M, 2009 dp5/HRK is a c-Jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons, Ma C, Ying C, Yuan Z, Song B, Li D, Liu Y, Lai B, Li W, Chen R, Ching YP, Li M, 2007

Areas of Focus

Signal transduction, gene regulation, and epigenetic mechanisms in neuronal apoptosis during hemorrhagic stroke
Pathogenesis and prevention of neuro-oncology and neuroimmune diseases

Publications

CD8+ T-cell predominance in autoimmune glial fibrillary acidic protein astrocytopathy, Zhongmin Yuan, Huilu Li, Lu Huang, Congcong Fu, Yaotang Chen, Cheng Zhi, Wei Qiu, Youming Long, 2021
Inhibition of HDAC4 Attenuated JNK/c-Jun-Dependent Neuronal Apoptosis and Early Brain Injury Following Subarachnoid Hemorrhage by Transcriptionally Suppressing MKK7, Liqiang Wu, Shulian Zeng, Yali Cao, Ziyan Huang, Sisi Liu, Huaidong Peng, Cheng Zhi, Shanshan Ma, Kunhua Hu, Zhongmin Yuan, 2019
Histone deacetylase 6 promotes growth of glioblastoma through the MKK7/JNK/c-Jun signaling pathway, Ziyan Huang, Yong Xia, Kunhua Hu, Shulian Zeng, Liqiang Wu, Sisi Liu, Cheng Zhi, Miaoling Lai, Danmin Chen, Longchang Xie, Zhongmin Yuan, 2020
MKK7 transcription positively or negatively regulated by SP1 and KLF5 depends on HDAC4 activity in glioma, Yezhong Wang, Yong Xia, Kunhua Hu, Minling Zeng, Cheng Zhi, Miaoling Lai, Liqiang Wu, Sisi Liu, Shulian Zeng, Ziyan Huang, Shanshan Ma, Zhongmin Yuan, 2019
Loss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim, Yanna Wu, Shanshan Ma, Yong Xia, Yangpeng Lu, Shiyin Xiao, Yali Cao, Sidian Zhuang, Xiangpeng Tan, Qiang Fu, Longchang Xie, Zhiming Li, Zhongmin Yuan, 2017
Essential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine, Ke Zhang, Ting Xu, Zhongmin Yuan, Zhisheng Wei, Vitor Nagai Yamaki, Mingfa Huang, Richard L Huganir, Xiang Cai, 2016
HDAC inhibitors suppress c-Jun/Fra-1-mediated proliferation through transcriptionally downregulating MKK7 and Raf1 in neuroblastoma cells, Weiwen He, Yanna Wu, Xiaomei Tang, Yong Xia, Guozhen He, Zhiqun Min, Chun Li, Shiqiu Xiong, Zhi Shi, Yongjian Lu, Zhongmin Yuan, 2016
Opposing roles for E2F1 in survival and death of cerebellar granule neurons, Yuan Z, Yao L, Li M, Liu S, He W, Lu Y, 2011
Opposing roles for ATF2 and c-Fos in c-Jun-mediated neuronal apoptosis, Yuan Z, Gong S, Luo J, Zheng Z, Song B, Ma S, Guo J, Hu C, Thiel G, Vinson C, Hu CD, Wang Y, Li M, 2009
dp5/HRK is a c-Jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons, Ma C, Ying C, Yuan Z, Song B, Li D, Liu Y, Lai B, Li W, Chen R, Ching YP, Li M, 2007

Neuronal Apoptosis Signal Transduction Gene Regulation Epigenetics Hemorrhagic Stroke Neuro-Oncology Neuroimmune Diseases Pathogenesis Prevention Treatment

Luyang Sun - Peking University

Hua Wang - Peking University

Zhenping Ming - Wuhan University

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