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Hua Wang
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Epigenetics
Cancer
Transcription
Ferroptosis
Metabolism
Gene Regulation
Cell Fate
Tumor Resistance
Targeted Therapy
Molecular Mechanisms
Areas of Focus
- Epigenetic regulation of cancer
- Transcriptional regulation mechanisms in cancer
- Ferroptosis in cancer metabolism
Work Experience
- 2023-09 - Present - Peking University, Assistant Professor, Researcher
- 2021-10 - 2023-09 - Memorial Sloan-Kettering Cancer Center, Research Fellow
- 2018-10 - 2021-09 - Memorial Sloan-Kettering Cancer Center, Research Associate
Academic Background & Achievements
- PhD: Nankai University
- National Overseas High-level Talents
Publications
- Roles of H3K4 methylation in biology and disease, Hua Wang, Kristian Helin, 2024
- H3K4me3 regulates RNA polymerase II promoter-proximal pause-release, Hua Wang, Zheng Fan, Pavel Shliaha, Matthew Miele, Ronald Hendrickson, Xuejun Jiang, Kristian Helin, 2023
- cGASing mitochondria to fend off ferroptosis, Hua Wang, Xuejun Jiang, 2023
- Colorectal cancer stem cell states uncovered by simultaneous single-cell analysis of transcriptome and telomeres, Hua Wang, Peng Gong, Sherman M. Weissman, Feng Qi, Xinghua Pan, Lin Liu, 2021
- BMP2/SMAD pathway activation in JAK2/p53-mutant megakaryocyte/erythroid progenitors promotes leukemic transformation, Bing Li, Wenbin An, Hua Wang, Timour Baslan, Shoron Mowla, Aishwarya Krishnan, Charles G. Mullighan, Kristian Helin, Scott W. Lowe, Ross L. Levine, Raajit K. Rampal, 2022
- SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling, Wei Gu, Hua Wang, Xiaofeng Huang, Judith Kraiczy, Pratik N.P. Singh, David Redmond, Randy Longman, Kristian Helin, Ramesh A. Shivdasani, Qiao Zhou, 2022
- Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones, Deguang Liang, Yan Feng, Fereshteh Zandkarimi, Hua Wang, Zeda Zhang, Wei Gu, Brent R. Stockwell, Xuejun Jiang, 2023
- Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals, Aditya Sankar, Faizaan Mohammad, Arun Sundaramurthy, Hua Wang, Mads Lerdrup, Tulin Tatar, Kristian Helin, 2022
- mTORC1 beyond anabolic metabolism: Regulation of cell death, Jiajun Zhu, Hua Wang, Xuejun Jiang, 2022
- Role of CD133 in human embryonic stem cell proliferation and teratoma formation, Hua Wang, Peng Gong, Jie Li, Lin Liu, 2020
- Telomere heterogeneity linked to metabolism and pluripotency state revealed by simultaneous analysis of telomere length and RNA-seq in the same human embryonic stem cell, Hua Wang, Kunshan Zhang, Yifei Liu, Tong Chen, Siguang Li, Lin Liu, 2017
Awards
- 2023: National Excellent Young Scientists Fund (Overseas)
