Areas of Focus
- Cell Biology: Regulation of autophagy-related proteins in health and disease, especially protein transport mediated by autophagy machinery in respiratory diseases
Work Experience
- Assistant Professor: UT Southwestern Medical Center, Department of Internal Medicine
- Team Lead/Supervisor: Howard Hughes Medical Institute, Beth Levine's team
Academic Background & Achievements
- PhD: Sun Yat-sen University, State Key Laboratory of Biocontrol
- Postdoctoral Training: UT Southwestern Medical Center, Howard Hughes Medical Institute
Publications
- JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy, Wei Y, Pattingre S, Sinha S, Bassik M, Levine B, 2008
- Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation, Wei Y, Sinha S, Levine B, 2008
- EGFR-Mediated Phosphorylation of Beclin 1 in Autophagy Suppression, Tumor Progression and Tumor Chemoresistance, Wei Y, Zou Z, Becker N, Anderson M, Sumpter R, Borczuk A, Xiao G, Peyton M, Minna J, Bhagat G and Levine B, 2013
- The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation, Wei Y, An Z, Zou Z, Sumpter R, Su M, Zang X, Sinha S, Gaestel M, Levine B, 2015
- Prohibitin 2 is an inner mitochondrial membrane mitophagy receptor, Wei Y, Chiang WC, Sumpter R Jr, Mishra P, Levine B, 2017
Awards
- International Patent