Professor | Erxia Shen | Asia Growth Partners

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Name	Erxia Shen
Contact Information	erxia_shen@gzhmu.edu.cn
Language ability	English, Chinese
Province	Guangdong

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Name

Erxia Shen

Contact Information

erxia_shen@gzhmu.edu.cn

Language ability

English, Chinese

Province

Guangdong

University/Lab Affiliation and Title	Guangzhou Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2014-2017: Postdoctoral Research at Dana-Farber Institute, Harvard University Guangzhou High-Level Talent Guangdong Province Thousand Hundred Ten Project Trainee Nanshan Scholar at Guangzhou Medical University
Work Experience	2014-2017 - Dana-Farber Institute, Harvard University - Postdoctoral Researcher Current - Guangzhou Medical University - Professor
Awards	Guangzhou High-Level Talent Guangdong Province Thousand Hundred Ten Project Trainee Guangdong Provincial Department of Education Young Backbone Teacher Trainee Nanshan Scholar Fifth Level Talent

University/Lab Affiliation and Title

Guangzhou Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2014-2017: Postdoctoral Research at Dana-Farber Institute, Harvard University
Guangzhou High-Level Talent
Guangdong Province Thousand Hundred Ten Project Trainee
Nanshan Scholar at Guangzhou Medical University

Work Experience

2014-2017 - Dana-Farber Institute, Harvard University - Postdoctoral Researcher
Current - Guangzhou Medical University - Professor

Awards

Guangzhou High-Level Talent
Guangdong Province Thousand Hundred Ten Project Trainee
Guangdong Provincial Department of Education Young Backbone Teacher Trainee
Nanshan Scholar Fifth Level Talent

Areas of Focus	Differentiation of CD4+T cells into follicular helper T cells and their role in autoimmune diseases Role and regulation of regulatory T cells in autoimmune diseases and tumors using conditional knockout mice Regulation of natural killer (NK) cells' anti-tumor and anti-infection activities in humans and mice
Publications	Low-dose IL-2 therapy in autoimmune diseases: An update review., Ruizhi Zhang, Yuyang Zhao, Xiangming Chen, Zhuoqing Zhuang, Xiaomin Li, Erxia Shen, 2023 Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review., Bu Jin, Ding Ruilian, Zhou Liangjia, Chen Xiangming, Shen Erxia, 2022 Increased TIGIT expressing NK cells with dysfunctional phenotype in AML patients correlated with poor prognosis., Guanfang Liu, Qi Zhang, Jingying Yang, Xiaomin Li, Luhua Xian, Wenmin Li, Ting Lin, Juan Cheng, Qiwen Lin, Xiuzhang Xu, Qin Li, Yu Lin, Maohua Zhou, Erxia Shen, 2022 Inhibition of COX-2 ameliorates murine liver schistosomiasis japonica through splenic cellular immunoregulation., Zhang Qi, Chen Lan, Ji Xiaofang, Tang Juanjuan, Fu Cheng, Huang Ting, Shen Erxia, Li Zi, 2022 Prediction of skin disease using a new cytological taxonomy based on cytology and pathology with deep residual learning method., Jin Bu, Yu Lin, Li-Qiong Qing, Gang Hu, Pei Jiang, Hai-Feng Hu, Er-Xia Shen, 2021 Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor., Erxia Shen, Hardis Rabe, Lin Luo, 2019 Chromatin remodeling by the NuRD complex regulates development of follicular helper and regulatory T cells., Erxia Shen, Qin Wang, Hardis Rabe, Wenquan Liu, Harvey Cantor, Jianmei W. Leavenworth, 2018 CD8+T cells expressing both PD-1 and TIGIT but not CD226 are dysfunctional in Acute Myeloid Leukemia (AML) patients., Wang M, Bu J, Zhou M, Sido J, Lin Y, Liu G, Lin Q, Xu X, Leavenworth JW, Shen E, 2018 Existence of Th22 in children and evaluation of IL-22 + CD4 + T, Th17, and other T cell effector subsets from healthy children compared to adults., Erxia Shen, Mengjie Wang, Hairui Xie, Ruqiong Zou, Qiwen Lin, Lili lai, Fujun Li, Zhimei Liang, Yanran Xu, Maohua Zhou, 2016 The effect of aging on the frequency, phenotype and cytokine production of human blood CD4 + CXCR5 + T follicular helper cells: comparison of aged and young subjects., Zhou M, Zou R, Gan H, Liang Z, Li F, Lin T, Luo Y, Cai X, He F, Shen E, 2014 The suppressive effect of CD25+Treg cells on Th1 differentiation requires cell-cell contact partially via TGF-β production., Shen E, Zhao K, Wu C, Yang B, 2011 TLR7/8 ligand, R-848, inhibits IgE synthesis by acting directly on B lymphocytes., Shen E, Lu L, Wu C, 2008 PIKA as an adjuvant enhances specific humoral and cellular immune responses following the vaccination of mice with HBsAg plus PIKA., Shen E, Li L, Li L, Feng L, Lu L, Yao Z, Lin H, Wu C, 2007

Areas of Focus

Differentiation of CD4+T cells into follicular helper T cells and their role in autoimmune diseases
Role and regulation of regulatory T cells in autoimmune diseases and tumors using conditional knockout mice
Regulation of natural killer (NK) cells' anti-tumor and anti-infection activities in humans and mice

Publications

Low-dose IL-2 therapy in autoimmune diseases: An update review., Ruizhi Zhang, Yuyang Zhao, Xiangming Chen, Zhuoqing Zhuang, Xiaomin Li, Erxia Shen, 2023
Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review., Bu Jin, Ding Ruilian, Zhou Liangjia, Chen Xiangming, Shen Erxia, 2022
Increased TIGIT expressing NK cells with dysfunctional phenotype in AML patients correlated with poor prognosis., Guanfang Liu, Qi Zhang, Jingying Yang, Xiaomin Li, Luhua Xian, Wenmin Li, Ting Lin, Juan Cheng, Qiwen Lin, Xiuzhang Xu, Qin Li, Yu Lin, Maohua Zhou, Erxia Shen, 2022
Inhibition of COX-2 ameliorates murine liver schistosomiasis japonica through splenic cellular immunoregulation., Zhang Qi, Chen Lan, Ji Xiaofang, Tang Juanjuan, Fu Cheng, Huang Ting, Shen Erxia, Li Zi, 2022
Prediction of skin disease using a new cytological taxonomy based on cytology and pathology with deep residual learning method., Jin Bu, Yu Lin, Li-Qiong Qing, Gang Hu, Pei Jiang, Hai-Feng Hu, Er-Xia Shen, 2021
Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor., Erxia Shen, Hardis Rabe, Lin Luo, 2019
Chromatin remodeling by the NuRD complex regulates development of follicular helper and regulatory T cells., Erxia Shen, Qin Wang, Hardis Rabe, Wenquan Liu, Harvey Cantor, Jianmei W. Leavenworth, 2018
CD8+T cells expressing both PD-1 and TIGIT but not CD226 are dysfunctional in Acute Myeloid Leukemia (AML) patients., Wang M, Bu J, Zhou M, Sido J, Lin Y, Liu G, Lin Q, Xu X, Leavenworth JW, Shen E, 2018
Existence of Th22 in children and evaluation of IL-22 + CD4 + T, Th17, and other T cell effector subsets from healthy children compared to adults., Erxia Shen, Mengjie Wang, Hairui Xie, Ruqiong Zou, Qiwen Lin, Lili lai, Fujun Li, Zhimei Liang, Yanran Xu, Maohua Zhou, 2016
The effect of aging on the frequency, phenotype and cytokine production of human blood CD4 + CXCR5 + T follicular helper cells: comparison of aged and young subjects., Zhou M, Zou R, Gan H, Liang Z, Li F, Lin T, Luo Y, Cai X, He F, Shen E, 2014
The suppressive effect of CD25+Treg cells on Th1 differentiation requires cell-cell contact partially via TGF-β production., Shen E, Zhao K, Wu C, Yang B, 2011
TLR7/8 ligand, R-848, inhibits IgE synthesis by acting directly on B lymphocytes., Shen E, Lu L, Wu C, 2008
PIKA as an adjuvant enhances specific humoral and cellular immune responses following the vaccination of mice with HBsAg plus PIKA., Shen E, Li L, Li L, Feng L, Lu L, Yao Z, Lin H, Wu C, 2007

Cd4+T Cells Follicular Helper T Cells Autoimmune Diseases Regulatory T Cells Conditional Knockout Mice Tumors Natural Killer Cells Anti-Tumor Anti-Infection Regulation

Xihui Gao - Fudan University

Wuyuan Lu - Fudan University

Xiaonan Wang - China Medical University

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