Professor | Yujia Xu | Asia Growth Partners

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Name	Yujia Xu
Contact Information	xuyujia@gzhmu.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Yujia Xu

Contact Information

xuyujia@gzhmu.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Guangzhou Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2014/09-2020/06 PhD: Soochow University 2010/09-2014/06 Bachelor's: Hubei University of Chinese Medicine
Work Experience	2022/10-present - Guangzhou Medical University - Professor 2020/09-2022/06 - Guangzhou Medical University - Postdoctoral Researcher

University/Lab Affiliation and Title

Guangzhou Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2014/09-2020/06 PhD: Soochow University
2010/09-2014/06 Bachelor's: Hubei University of Chinese Medicine

Work Experience

2022/10-present - Guangzhou Medical University - Professor
2020/09-2022/06 - Guangzhou Medical University - Postdoctoral Researcher

Areas of Focus	Post-translational modification of proteins Ferroptosis Discovery of anti-tumor small molecule drugs
Publications	Targeting the Otub1/c-Maf axis for the treatment of multiple myeloma., Xu Y, Xu M, Tong J, Tang X, Chen J, Chen X, Zhang Z, Cao B, Moran MF, Wu D, Mao X., 2021 The ubiquitin conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis., Xu Y#, Zhang Z#, Li J#, Tong J, Cao B, Taylor P, Tang X, Wu D, Moran M, Zeng Y, Mao X., 2017 Anti-bacterial and anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 and c-Maf., Yujia Xu#, Tong Sun#, Kun Zeng, Min Xu, Jinhao Chen, Xiaofeng Xu, Zubin Zhang, Biyin Cao, Xiaowen Tang, Depei Wu, Yan Kong, Yuanying Zeng, Xinliang Mao., 2020 Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia., Zhuang H, Ren Y, Mao C, Zhong Y, Zhang Z, Cao B, Zhang Y, Huang J, Xu G, Huang Z, Xu Y, Mao X., 2022 Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis., Tong Sun#, Yujia Xu#, Zhuan Xu#, Biyin Cao, Zubin Zhang, Qi Wang, Yan Kong, Xinliang Mao., 2021 Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis., Xue-Han Chen#, Yujia Xu#, Xiao-Ge Wang#, Peng Lin, Bi-Yin Cao, Yuan-Ying Zeng, Qi Wang, Zu-Bin Zhang, Xin-Liang Mao, Tie Zhang., 2019 Novel conjugates of endoperoxide and 4-anilinoquinazoline induce myeloma cell apoptosis by inhibiting the IGF1-R/AKT/mTOR signaling pathway., Xu Y#, Zeng K#, Wang X, Zhang J, Cao B, Zhang Z, Qiao C, Xu X, Wang Q, Zeng Y, Mao X., 2020 A novel STAT3 inhibitor negatively modulates platelet activation and aggregation., Zhuan Xu#, Yu-Jia Xu#, Ya-Nan Hao#, Li-Jie Ren, Zu-Bin Zhang, Xin Xu, Bi-Yin Cao, Ke-Sheng Dai, Li Zhu, Qi Fang, Yan Kong, Xin-Liang Mao*., 2017

Areas of Focus

Post-translational modification of proteins
Ferroptosis
Discovery of anti-tumor small molecule drugs

Publications

Targeting the Otub1/c-Maf axis for the treatment of multiple myeloma., Xu Y, Xu M, Tong J, Tang X, Chen J, Chen X, Zhang Z, Cao B, Moran MF, Wu D*, Mao X*., 2021
The ubiquitin conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis., Xu Y#, Zhang Z#, Li J#, Tong J, Cao B, Taylor P, Tang X, Wu D, Moran M, Zeng Y*, Mao X*., 2017
Anti-bacterial and anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 and c-Maf., Yujia Xu#, Tong Sun#, Kun Zeng, Min Xu, Jinhao Chen, Xiaofeng Xu, Zubin Zhang, Biyin Cao, Xiaowen Tang, Depei Wu, Yan Kong, Yuanying Zeng*, Xinliang Mao*., 2020
Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia., Zhuang H, Ren Y, Mao C, Zhong Y, Zhang Z, Cao B, Zhang Y, Huang J, Xu G, Huang Z, Xu Y*, Mao X*., 2022
Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis., Tong Sun#, Yujia Xu#, Zhuan Xu#, Biyin Cao, Zubin Zhang, Qi Wang*, Yan Kong*, Xinliang Mao*., 2021
Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis., Xue-Han Chen#, Yujia Xu#, Xiao-Ge Wang#, Peng Lin, Bi-Yin Cao, Yuan-Ying Zeng, Qi Wang, Zu-Bin Zhang*, Xin-Liang Mao*, Tie Zhang*., 2019
Novel conjugates of endoperoxide and 4-anilinoquinazoline induce myeloma cell apoptosis by inhibiting the IGF1-R/AKT/mTOR signaling pathway., Xu Y#, Zeng K#, Wang X, Zhang J, Cao B, Zhang Z, Qiao C, Xu X, Wang Q, Zeng Y, Mao X., 2020
A novel STAT3 inhibitor negatively modulates platelet activation and aggregation., Zhuan Xu#, Yu-Jia Xu#, Ya-Nan Hao#, Li-Jie Ren, Zu-Bin Zhang, Xin Xu, Bi-Yin Cao, Ke-Sheng Dai, Li Zhu, Qi Fang*, Yan Kong*, Xin-Liang Mao*., 2017

Protein Modification Ferroptosis Anti-Tumor Small Molecules Drug Discovery Cancer Research Biochemistry Molecular Biology Cell Death Therapeutics

Li Jing - Chongqing Medical University

Dilong Chen - Chongqing Medical University

Guoheng Xu - Peking University

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