Areas of Focus
- 蛋白质翻译后修饰
- 铁死亡
- 抗肿瘤小分子药物的发现
Work Experience
- 2022/10至今 - 广州医科大学 - 教授
- 2020/09-2022/06 - 广州医科大学 - 博后
Academic Background & Achievements
- 2014/09-2020/06 博士: 苏州大学
- 2010/09-2014/06 学士: 湖北中医药大学
Publications
- 靶向Otub1/c-Maf轴治疗多发性骨髓瘤。, Xu Y, Xu M, Tong J, Tang X, Chen J, Chen X, Zhang Z, Cao B, Moran MF, Wu D*, Mao X*., 2021
- 泛素结合酶UBE2O调节c-Maf稳定性并诱导骨髓瘤细胞凋亡。, Xu Y#, Zhang Z#, Li J#, Tong J, Cao B, Taylor P, Tang X, Wu D, Moran M, Zeng Y*, Mao X*., 2017
- 抗菌和抗病毒的南昌霉素通过靶向Otub1和c-Maf显示抗骨髓瘤活性。, Yujia Xu#, Tong Sun#, Kun Zeng, Min Xu, Jinhao Chen, Xiaofeng Xu, Zubin Zhang, Biyin Cao, Xiaowen Tang, Depei Wu, Yan Kong, Yuanying Zeng*, Xinliang Mao*., 2020
- 诱导锌指蛋白RNF6自泛素化治疗骨髓瘤和慢性髓性白血病。, Zhuang H, Ren Y, Mao C, Zhong Y, Zhang Z, Cao B, Zhang Y, Huang J, Xu G, Huang Z, Xu Y*, Mao X*., 2022
- 草药acevaltrate通过抑制Otub1/c-Maf轴诱导骨髓瘤细胞凋亡。, Tong Sun#, Yujia Xu#, Zhuan Xu#, Biyin Cao, Zubin Zhang, Qi Wang*, Yan Kong*, Xinliang Mao*., 2021
- 甲苯咪唑通过抑制USP5/c-Maf轴引发强效抗骨髓瘤活性。, Xue-Han Chen#, Yujia Xu#, Xiao-Ge Wang#, Peng Lin, Bi-Yin Cao, Yuan-Ying Zeng, Qi Wang, Zu-Bin Zhang*, Xin-Liang Mao*, Tie Zhang*., 2019
- 新型内过氧化物和4-苯胺喹唑啉结合物通过抑制IGF1-R/AKT/mTOR信号通路诱导骨髓瘤细胞凋亡。, Xu Y#, Zeng K#, Wang X, Zhang J, Cao B, Zhang Z, Qiao C, Xu X, Wang Q, Zeng Y, Mao X., 2020
- 一种新型STAT3抑制剂负调节血小板活化和聚集。, Zhuan Xu#, Yu-Jia Xu#, Ya-Nan Hao#, Li-Jie Ren, Zu-Bin Zhang, Xin Xu, Bi-Yin Cao, Ke-Sheng Dai, Li Zhu, Qi Fang*, Yan Kong*, Xin-Liang Mao*., 2017