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Xiao-Yang Xu
Basic Medical Sciences
Guangzhou Medical University
Guangdong
Language: Chinese, English
Vascular Physiology
Atherosclerosis
Macrophage
Lysosome
Cholesterol
Regulation
Mechanism
Research
Health
Disease
Areas of Focus
- Vascular Physiology: Regulation of cholesterol by macrophage lysosomes during atherosclerosis formation
Academic Background & Achievements
- PhD: Sun Yat-sen University, Zhongshan School of Medicine
Publications
- Short-chain fatty acid butyrate acid attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice and the underlying mechanism., Hong-Bo Bai, Ping Yang, Han-Bin Zhang, Yu-Lin Liu, Shu-Xiang Fang, Xiao-Yang Xu, 2021
- Nicotinic acid promotes lysosomal free cholesterol efflux via LXRα/NPC1 pathway in macrophages., YANG Ping, ZHANG Han-bin, LIU Yu-lin, FANG Shu-xiang, LI Ping, XU Xiao-yang, 2020
- Elevated luteinizing hormone contributes to atherosclerosis formation by inhibiting nitric oxide synthesis via PI3K/Akt pathway., Xuan Meng, Xiaosa Li, Xingyan Xu, Ping Li, Yiwen Chen, Xiaodong Fu, Xiaoyang Xu, 2019
- GPER1 promotes estrogen receptor negative breast cancer cell migration and invasion via non-genomic activation of c-Src/NF-κB/focal adhesion kinase cascade., Li Xiao-Sa, Yan Qing, Xu Xing-Yan, Chen Wei-Yu, Li Ping, Xiang Qiu-Ling, Xu Xiao-Yang, Fu Xiao-Dong, 2018
- Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXRa signalling pathway in oxLDL-loaded macrophages., Xiaoyang Xu, Aolin Zhang, Matthew S. Halquist, Xinxu Yuan, Scott C. Henderson, William L. Dewey, Pin-Lan Li, Ningjun Li, Fan Zhang, 2017
- Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38-/- mice., Xiaoyang Xu, Xinxu Yuan, Ningjun Li, William L. Dewey, Pin-Lan Li, Fan Zhang, 2016
- Concentration-dependent diversification effects of free cholesterol loading on macrophage viability and polarization., Xiaoyang Xu, Aolin Zhang, Ningjun Li, Pin-Lan Li, Fan Zhang, 2015
- Effect of slow abdominal breathing combined with biofeedback on blood pressure and heart rate variability in prehypertension., Shu-Zhen Wang, Sha Li, Xiao-Yang Xu, Gui-Ping Lin, Li Shao, Yan Zhao, Ting Huai Wang, 2010
- Biofeedback treatment of prehypertension: analyses of efficacy, heart rate variability, and EEG approximate entropy., Xu XY, Gao J, Ling D, Wang TH, 2007
Awards
- 2019: First Prize in the 'Higher Education Medical Virtual Simulation Experiment Teaching Project Competition'
- 2018: Second Prize in the 'Second Taimeng Cup University Innovation Functional Experiment Design Competition'
