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Ling Chen
English, Chinese
Guangdong
Guangzhou Medical University
Basic Medical Sciences
  • 1979-1985: Studied at Shanghai First Medical College, Medical Department
  • 1985-1991: PhD in Biochemistry and Molecular Biology from Indiana University School of Medicine
  • Achievement: Founding Director of the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences (2004-2008)
  • Achievement: Recipient of the National Outstanding Youth Science Fund (Foreign)
  • 1992-1993: Postdoctoral Research at Harvard Medical School and Dana-Farber Cancer Institute
  • 1994-1996: Instructor at Harvard Medical School
  • 1997-2001: Senior Research Fellow at Merck & Co.
  • Current: Chairman of Guangzhou Enbao Biopharmaceutical Co., Ltd.
  • National Outstanding Youth Science Fund (Foreign)
Vaccine Development
Antibody Research
Cancer Drug Development
  • Monoclonal antibodies against Zika virus NS1 protein confer protection via Fcg receptor-dependent and -independent pathways., Yu L, Liu X, Ye X, Su W, Zhang X, Deng W, Luo J, Xiang M, Guo W, Zhang S, Xu W, Yan Q, Wang Q, Cui Y, Wu C, Guo W, Niu X, Zhang F, Lei C, Qu L, Chen L, Feng L., 2021
  • An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques., Feng L, Wang Q, Shan C, Yang C, Feng Y, Wu J, Liu X, Zhou Y, Jiang R, Hu P, Liu X, Zhang F, Li P, Niu X, Liu Y, Zheng X, Luo J, Sun J, Gu Y, Liu B, Xu Y, Li C, Pan W, Zhao J, Ke C, Chen X, Xu T, Zhong N, Guan S, Yuan Z, Chen L., 2020
  • Human desmoglein-2 and human CD46 mediate Ad55 infection but human desmoglein-2 plays the major roles., Feng Y, Yi C, Liu X, Qu L, Su W, Shu T, Zheng X, Ye X, Luo J, Hao M, Sun X, Li L, Liu X, Yang C, Guan S, Chen L, Feng L., 2020
  • Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients., Sun B, Feng Y, Mo X, Zheng P, Wang Q, Li P, Peng P, Liu X, Chen Z, Huang H, Zhang F, Luo W, Niu X, Hu P, Wang L, Peng H, Huang Z, Feng L, Li F, Zhong N, Chen L., 2020
  • L226Q mutation on influenza H7N9 virus hemagglutinin increases receptor-binding avidity and leads to biased antigenicity evaluation., Wang Y, Lv Y, Niu X, Dong J, Feng P, Li Q, Xu W, Li J, Li C, Li J, Luo J, Li Z, Liu Y, Tan Y-J, Pan W, Chen L., 2020
  • Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients., Niu X, Li S, Li P, Pan W, Wang Q, Feng Y, Mo X, Yan Q, Ye X, Luo J, Qu L, Weber D, Byrne-Steele ML, Wang Z, Yu F, Li F, Myers RM, Lotze MT, Zhong N, Han J, Chen L., 2020
  • Longitudinal analysis of the antibody repertoire of a Zika virus-infected patient revealed dynamic changes in antibody response., Niu X, Yan Q, Yao Z, Zhang F, Qu L, Wang C, Wang C, Lei H, Chen Z, Liang R, Luo J, Wang Q, Zhao L, Zhang Y, Luo K, Wang L, Wu H, Liu T, Li P, Zheng Z, Tan Y, Feng L, Zhang Z, Han J, Zhang F, Chen L., 2020
  • Arsenic Trioxide Impacts Viral Latency and Delays Viral Rebound after Termination of ART in Chronically SIV-Infected Macaques., Qing Yang, Fengling Feng, Pingchao Li, Enxiang Pan, Chunxiu Wu, Yizi He, Fan Zhang, Jin Zhao, Ruiting Li, Liqiang Feng, Fengyu Hu, Linghua Li, Huachun Zou, Weiping Cai, Thomas Lehner, Caijun Sun, Ling Chen., 2019
  • Convalescent patient-derived monoclonal antibodies targeting different epitopes of E protein confer protection against Zika virus in a neonatal mouse model., Niu X, Zhao L, Qu L, Yao Z, Zhang F, Yan Q, Zhang S, Liang R, Chen P, Luo J, Xu W, Lv H, Liu X, Lei H, Yi C, Li P, Wang Q, Wang Y, Yu L, Zhang X, Bryan AL, Davidson E, Doranz BJ, Feng L, Pan W, Zhang F, Chen L., 2019
  • Chloroquine inhibits endosomal viral RNA release and autophagy-dependent viral replication and effectively prevents maternal to fetal transmission of Zika virus., Zhang S, Yi C, Li C, Zhang F, Peng J, Wang Q, Liu X, Ye X, Li P, Wu M, Yan Q, Guo W, Niu X, Feng L, Pan W, Chen L, Qu L., 2019
  • Hexon and fiber of adenovirus type 14 and 55 are major targets of neutralizing antibody but only fiber-specific antibody contributes to cross-neutralizing activity., Feng Y, Sun X, Ye X, Wang J, Zheng X, Liu X, Yi C, Hao M, Wang Q, Li F, Xu W, Li L, Li C, Zhou R, Chen L, Feng L., 2018
  • Immunization with an adenovirus-vectored TB vaccine containing Ag85A-Mtb32 effectively alleviates allergic asthma., Zhang Y, Feng Y, Li L, Ye X, Wang J, Wang Q, Li P, Li N, Zheng X, Gao X, Li C, Li F, Sun B, Lai K, Su Z, Zhong N, Chen L, Feng L., 2018
  • Seroprevalence of Neutralizing Antibodies to Human Adenovirus Type 4 and 7 in Healthy Populations From Southern China., Ye X, Xiao L, Zheng X, Wang J, Shu T, Feng Y, Liu X, Su W, Wang Q, Li C, Chen L, Feng L., 2018
  • An adenovirus serotype 2-vectored ebolavirus vaccine generates robust antibody and cell-mediated immune responses in mice and rhesus macaques., Feng Y, Li C, Hu P, Wang Q, Zheng X, Zhao Y, Shi Y, Yang S, Yi C, Wu C, Qu L, Feng Y, Xu W, Li Y, Sun C, Gao FG, Xia X, Feng L, Chen L., 2018
  • Immune Protection of SIV Challenge by PD-1 Blockade During Vaccination in Rhesus Monkeys., Pan E, Feng F, Li P, Yang Q, Ma X, Wu C, Zhao J, Yan H, Chen R, Chen L, Sun C., 2018
  • Phenotypic Characterization of Chinese Rhesus Macaque Plasmablasts for Cloning Antigen-Specific Monoclonal Antibodies., Zhang F, Wang L, Niu X, Li J, Luo J, Feng Y, Yang Y, He P, Fan W, Liang R, Zheng Z, Pan W, Li C, Tan YJ, Yu H, Chen L, Li P., 2019
  • Incorporation of NS1 and prM/M are important to confer effective protection of adenovirus-vectored Zika virus vaccine carrying E protein., Liu X, Qu L, Ye X, Yi C, Zheng X, Hao M, Wan Su W, Zhipeng Yao Z, Chen P, Zhang S, Feng Y, Wang Q, Yan Q, Li P, Li H, Li F, Pan W, Niu X, Xu R, Feng L, Chen L., 2018
Vaccine Antibody Cancer Drug Development Biomedicine Infectious Diseases Clinical Trials Patents Immunology Molecular Biology

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