1979-1985: Studied at Shanghai First Medical College, Medical Department
1985-1991: PhD in Biochemistry and Molecular Biology from Indiana University School of Medicine
Achievement: Founding Director of the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences (2004-2008)
Achievement: Recipient of the National Outstanding Youth Science Fund (Foreign)
1992-1993: Postdoctoral Research at Harvard Medical School and Dana-Farber Cancer Institute
1994-1996: Instructor at Harvard Medical School
1997-2001: Senior Research Fellow at Merck & Co.
Current: Chairman of Guangzhou Enbao Biopharmaceutical Co., Ltd.
National Outstanding Youth Science Fund (Foreign)
Research
Vaccine Development Antibody Research Cancer Drug Development
Monoclonal antibodies against Zika virus NS1 protein confer protection via Fcg receptor-dependent and -independent pathways., Yu L, Liu X, Ye X, Su W, Zhang X, Deng W, Luo J, Xiang M, Guo W, Zhang S, Xu W, Yan Q, Wang Q, Cui Y, Wu C, Guo W, Niu X, Zhang F, Lei C, Qu L, Chen L, Feng L., 2021
An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques., Feng L, Wang Q, Shan C, Yang C, Feng Y, Wu J, Liu X, Zhou Y, Jiang R, Hu P, Liu X, Zhang F, Li P, Niu X, Liu Y, Zheng X, Luo J, Sun J, Gu Y, Liu B, Xu Y, Li C, Pan W, Zhao J, Ke C, Chen X, Xu T, Zhong N, Guan S, Yuan Z, Chen L., 2020
Human desmoglein-2 and human CD46 mediate Ad55 infection but human desmoglein-2 plays the major roles., Feng Y, Yi C, Liu X, Qu L, Su W, Shu T, Zheng X, Ye X, Luo J, Hao M, Sun X, Li L, Liu X, Yang C, Guan S, Chen L, Feng L., 2020
Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients., Sun B, Feng Y, Mo X, Zheng P, Wang Q, Li P, Peng P, Liu X, Chen Z, Huang H, Zhang F, Luo W, Niu X, Hu P, Wang L, Peng H, Huang Z, Feng L, Li F, Zhong N, Chen L., 2020
L226Q mutation on influenza H7N9 virus hemagglutinin increases receptor-binding avidity and leads to biased antigenicity evaluation., Wang Y, Lv Y, Niu X, Dong J, Feng P, Li Q, Xu W, Li J, Li C, Li J, Luo J, Li Z, Liu Y, Tan Y-J, Pan W, Chen L., 2020
Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients., Niu X, Li S, Li P, Pan W, Wang Q, Feng Y, Mo X, Yan Q, Ye X, Luo J, Qu L, Weber D, Byrne-Steele ML, Wang Z, Yu F, Li F, Myers RM, Lotze MT, Zhong N, Han J, Chen L., 2020
Longitudinal analysis of the antibody repertoire of a Zika virus-infected patient revealed dynamic changes in antibody response., Niu X, Yan Q, Yao Z, Zhang F, Qu L, Wang C, Wang C, Lei H, Chen Z, Liang R, Luo J, Wang Q, Zhao L, Zhang Y, Luo K, Wang L, Wu H, Liu T, Li P, Zheng Z, Tan Y, Feng L, Zhang Z, Han J, Zhang F, Chen L., 2020
Arsenic Trioxide Impacts Viral Latency and Delays Viral Rebound after Termination of ART in Chronically SIV-Infected Macaques., Qing Yang, Fengling Feng, Pingchao Li, Enxiang Pan, Chunxiu Wu, Yizi He, Fan Zhang, Jin Zhao, Ruiting Li, Liqiang Feng, Fengyu Hu, Linghua Li, Huachun Zou, Weiping Cai, Thomas Lehner, Caijun Sun, Ling Chen., 2019
Convalescent patient-derived monoclonal antibodies targeting different epitopes of E protein confer protection against Zika virus in a neonatal mouse model., Niu X, Zhao L, Qu L, Yao Z, Zhang F, Yan Q, Zhang S, Liang R, Chen P, Luo J, Xu W, Lv H, Liu X, Lei H, Yi C, Li P, Wang Q, Wang Y, Yu L, Zhang X, Bryan AL, Davidson E, Doranz BJ, Feng L, Pan W, Zhang F, Chen L., 2019
Chloroquine inhibits endosomal viral RNA release and autophagy-dependent viral replication and effectively prevents maternal to fetal transmission of Zika virus., Zhang S, Yi C, Li C, Zhang F, Peng J, Wang Q, Liu X, Ye X, Li P, Wu M, Yan Q, Guo W, Niu X, Feng L, Pan W, Chen L, Qu L., 2019
Hexon and fiber of adenovirus type 14 and 55 are major targets of neutralizing antibody but only fiber-specific antibody contributes to cross-neutralizing activity., Feng Y, Sun X, Ye X, Wang J, Zheng X, Liu X, Yi C, Hao M, Wang Q, Li F, Xu W, Li L, Li C, Zhou R, Chen L, Feng L., 2018
Immunization with an adenovirus-vectored TB vaccine containing Ag85A-Mtb32 effectively alleviates allergic asthma., Zhang Y, Feng Y, Li L, Ye X, Wang J, Wang Q, Li P, Li N, Zheng X, Gao X, Li C, Li F, Sun B, Lai K, Su Z, Zhong N, Chen L, Feng L., 2018
Seroprevalence of Neutralizing Antibodies to Human Adenovirus Type 4 and 7 in Healthy Populations From Southern China., Ye X, Xiao L, Zheng X, Wang J, Shu T, Feng Y, Liu X, Su W, Wang Q, Li C, Chen L, Feng L., 2018
An adenovirus serotype 2-vectored ebolavirus vaccine generates robust antibody and cell-mediated immune responses in mice and rhesus macaques., Feng Y, Li C, Hu P, Wang Q, Zheng X, Zhao Y, Shi Y, Yang S, Yi C, Wu C, Qu L, Feng Y, Xu W, Li Y, Sun C, Gao FG, Xia X, Feng L, Chen L., 2018
Immune Protection of SIV Challenge by PD-1 Blockade During Vaccination in Rhesus Monkeys., Pan E, Feng F, Li P, Yang Q, Ma X, Wu C, Zhao J, Yan H, Chen R, Chen L, Sun C., 2018
Phenotypic Characterization of Chinese Rhesus Macaque Plasmablasts for Cloning Antigen-Specific Monoclonal Antibodies., Zhang F, Wang L, Niu X, Li J, Luo J, Feng Y, Yang Y, He P, Fan W, Liang R, Zheng Z, Pan W, Li C, Tan YJ, Yu H, Chen L, Li P., 2019
Incorporation of NS1 and prM/M are important to confer effective protection of adenovirus-vectored Zika virus vaccine carrying E protein., Liu X, Qu L, Ye X, Yi C, Zheng X, Hao M, Wan Su W, Zhipeng Yao Z, Chen P, Zhang S, Feng Y, Wang Q, Yan Q, Li P, Li H, Li F, Pan W, Niu X, Xu R, Feng L, Chen L., 2018